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2-(Boc-oxyimino)-2-phenylacetonitrile. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-(tert-Butoxycarbonyloxyimino)-2-phenyl-acetonitrile, Boc-ON. Product Category: tert-Butoxycarbonylation (Boc) Reagents. CAS No. 58632-95-4. Molecular formula: C13H14N2O3. Mole weight: 246.26. Purity: 0.99. Product ID: ACM58632954. Alfa Chemistry ISO 9001:2015 Certified.
It is used as an amino protective reagent in peptide synthesis. Synonyms: 2-Butoxycarbonyloximino-2-phenylAcetonitrile; BOC-ON 25GR; BOC-ON 5GR; BOC-ON; 2-(tert-Butoxycarbonyloxyimino)-2-phenylAcetonitrile; 2-(Boc-oxyimino)-2-phenylAcetonitrile; Carbonic acid, (cyanophenylmethylene)azanyl 1,1-dimethylethyl ester; N-((tert-Butoxycarbonyl)oxy)benzimidoyl cyanide; EINECS 261-370-9; (Z)-N-(tert-butoxycarbonyloxy)benzimidoyl cyanide; Boc-ON. Grades: ≥ 99 % (HPLC). CAS No. 58632-95-4. Molecular formula: C13H14N2O3. Mole weight: 246.26.
2- (tert-Butoxycarbonyl oxyimino) phenyl acetonitri le
2- (tert-Butoxycarbonyl oxyimino) phenyl acetonitri le is used as a reagent in the synthesis of phosphono methyl ornithine. Also used in the preparation of cholesterol-tagged natural fusion-protein-derived peptides with potent antiviral activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 58632-95-4. Pack Sizes: 5g, 10g. Molecular Formula: C13H14N2O3. US Biological Life Sciences.
A cell-permeable phenyl sulfonyl oxyimi nocyclohexadienone compound that acts as a potent, selective, and reversible inhibitor of p300 histone acetyl transferase (IC50 = 1.98uM). Shown to occupy Ac-CoA binding pocket of p300, and less potent to CBP, PCAF, GCN5 and GNAT. Suppresses Histone H3 and H4 acetylation in triple negative breast cancer cell line MDAMB-468 as well as in HCT116 cell line and blocks p300-mediated STAT3 phosphorylation in pancreatic cancer cell line MIA Paca-2. Does neither inhibit the activities of histone deacetylases 1, 6, and 11 nor 8-diverse histone methyltransferases tested (DOT1, EZH1, G9a, PRMT1, SETD2, SET7-9, SMYD2, and SUV39H2). Reported to suppress tumor growth in mice bearing tumor xenografts of MDAMB-468 cell line (at 500ug/100ul, i.p. twice a week). Group: Biochemicals. Grades: Highly Purified. CAS No. 321695-57-2. Pack Sizes: 10mg. Molecular Formula: C??H??NO?S. US Biological Life Sciences.