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| Product | Description | |
|---|---|---|
| Oxymetazoline Hydrochloride | Vasoconstrictor, used as a nasal decongestant. An ingredient of Drixin. Oxymetazoline is an agonist of α1- and α2-adrenergic receptors (α1- and α2-ARs; Kds = 6, 320, and 390 nM for α1A-, α1B-, and α1D-ARs, respectively, Ki = 15 nM for α2-AR).1,2 It is also an agonist of the serotonin (5-HT) receptor subtype 5-HT1 (Kds = 4.68, 25.7, and 5.01 nM for 5-HT1A, 5-HT1B, and 5-HT1D, respectively).3 Oxymetazoline increases intracellular calcium levels in CHO cells transfected with the α1A-AR (EC50 = 40.7 nM), but does not increase it measurably in cells transfected with the α1B- or α1D-AR (EC50s = 79.4 and 240 nM, respectively).1 It acts as a partial agonist of the α2-AR in isolated perfused rat heart (IC50 = 63 nM and EC50 = 13.5 nM for norepinephrine release).4,5 Oxymetazoline also acts as an agonist and antagonist of the 5-HT1C receptor in the presence of methiothepin (Kd = 110 nM; Item No. 23138) and clonidine (Kd = 257 Group: Biochemicals. Alternative Names: 3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol Hydrochloride; 2-(4-tert-Butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoline Hydrochloride; 6-tert-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol Hydrochloride; Hazol; Navasin; Navisin; Nezeril; Oxylazine; Rhinofrenol; Rhinolitan; Sinerol. Grades: Highly Purified. CAS No. 2315-2-8. Pack Sizes: 100mg, 500mg, 1g, 5g. Molecular Formula: C??H??ClN?O, Molecular Weight: 296.84. US Biological Life Sciences. |  Worldwide |
| Oxymetazoline Hydrochloride EP impurity A | Oxymetazoline Hydrochloride EP impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1391194-44-7. Molecular Formula: C16H26N2O2. Mole Weight: 278.4. Catalog: APB1391194447. |  |
| Oxymetazoline Hydrochloride EP impurity B | Oxymetazoline Hydrochloride EP impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 526-36-3. Molecular Formula: C16H24N2. Mole Weight: 244.38. Catalog: APB526363. | |
| Oxymetazoline Hydrochloride EP impurity C | Oxymetazoline Hydrochloride EP impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 55699-13-3. Molecular Formula: C14H21NO2. Mole Weight: 235.33. Catalog: APB55699133. | |
| Oxymetazoline Hydrochloride EP impurity D | Oxymetazoline Hydrochloride EP impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 55699-12-2. Molecular Formula: C14H20O3. Mole Weight: 236.31. Catalog: APB55699122. | |
| Oxymetazoline Hydrochloride EP impurity E | Oxymetazoline Hydrochloride EP impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 55699-10-0. Molecular Formula: C14H19NO. Mole Weight: 217.31. Catalog: APB55699100. | |
| Dehydro oxymetazoline hydrochloride | Dehydro oxymetazoline hydrochloride. Group: Biochemicals. Alternative Names: 6-(1,1-Dimethylethyl)-3-(1H-imidazol-2-ylmethyl)-2,4-dimethylphenol hydrochloride; 6-(1,1-dimethylethyl)-3-(1H-imidazol-2-ylmethyl)-2,4-dimethylphenol monohydrochloride. Grades: Highly Purified. CAS No. 205035-03-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H23ClN2O. US Biological Life Sciences. | Worldwide |
| Oxymetazoline Impurity C | An impurity of Oxymetazoline which is a vasoconstrictor to relieve nasal congestion, used in the form of oxymetazoline hydrochloride. Grades: > 95%. Molecular formula: C14H21NO2. Mole weight: 235.33. |  |
| Oxymetazoline Impurity E | An impurity of Oxymetazoline which is a vasoconstrictor to relieve nasal congestion, used in the form of oxymetazoline hydrochloride. Grades: > 95%. Molecular formula: C14H19NO. Mole weight: 217.31. | |
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