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Ozagrel is an antiplatelet agent working as a thromboxane A2 (TXA2) synthesis inhibitor. It has been a clinical objective for many years. lt is a 1-alkyl imidazole derivative that acts as a selective inhibitor of TXA2 with an IC50 of 11 nM. lt was selected as the best compound of highly selective inhibitors of TXA2 synthase. lt increased 6-keto-PGF1 alpha in various isolated cells and tissues. It blunted and delayed the decrease in cardiac output and maintained end-systolic pressure-diameter relation, +dp/dt, and lung lymph flow at baseline values. Uses: Ozagrel was selected as the best compound of highly selective inhibitors of txa2 synthase. lt increased 6-keto-pgf1 alpha in various isolated cells and tissues. Synonyms: OKY046; OKY 046; OKY-046; 2-Propenoic acid,3-[4-(1H-imidazol-1- ylmethyl)phenyl]-,(2E)-;(E)-p-(Imidazol-1-ylmethyl)cinnamic acid;(E)-3-[4-(imidazol-1-ylmethyl)phenyl]prop-2-enoic acid;(E)-3-[P-(imidazol-1-ylmethyl)phenyl]prop-2-enoic acid. Grades: >98%. CAS No. 82571-53-7. Molecular formula: C13H12N2O2. Mole weight: 228.25.
Ozagrel hydrochloride
Ozagrel hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 74003-18-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Ozagrel hydrochloride
Ozagrel hydrochloride is a thromboxane synthetase inhibitor with IC50 value of 4 nM. Uses: Enzyme inhibitors. Synonyms: (2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 74003-18-2. Molecular formula: C13H12N2O2.HCl. Mole weight: 264.71.
Ozagrel Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1332370-00-9. Molecular formula: C10H10O3. Mole weight: 178.19. Catalog: APB1332370009.
Ozagrel Impurity 2
Ozagrel Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 100688-45-7. Molecular formula: C13H14O4. Mole weight: 234.25. Catalog: APB100688457.
Ozagrel Methyl Ester
Ozagrel Methyl Ester is an impurity of Ozagrel, an antiplatelet drug that acts as a thromboxane A2 synthesis inhibitor. Synonyms: methyl (E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)acrylate; (2E)-3-[4-(1H-imidazol-1-ylmethyl)phenyl]-methyl Ester 2-Propenoic Acid. CAS No. 956932-46-0. Molecular formula: C14H14N2O2. Mole weight: 242.27.
Ozagrel sodium
Ozagrel is a thromboxane A2 synthase inhibitor used as an antiplatelet agent. It reduces the risk of neurological impairment and the volume of brain damage. Synonyms: KCT-0809; Cataclot; Xanbo; (E)-3-[4-(imidazol-1-ylmethyl)phenyl]prop-2-enoate sodium. CAS No. 189224-26-8. Molecular formula: C13H11N2O2·Na. Mole weight: 250.23.
Ozagrel sodium
Ozagrel sodium. Group: Biochemicals. Grades: Highly Purified. CAS No. 189224-26-8,130952-46-4. Pack Sizes: 50mg, 100g, 250g, 500g, 1kg. US Biological Life Sciences.
Worldwide
(E)-Ozagrel hydrochloride
Ozagrel HCl is a selective thromboxane A(2) (TXA(2)) synthetase inhibitor with IC50 of 11 nM for rabbit platelet, used for the improvement of postoperative cerebrovascular contraction and accompanying cerebral ischaemia. Uses: Enzyme inhibitors. Synonyms: ozagrel hydrochloride; OKY-046 hydrochloride. Grades: >98%. CAS No. 78712-43-3. Molecular formula: C13H13ClN2O2. Mole weight: 264.71.
1,3-bis(4-((E)-2-carboxyvinyl)benzyl)-1H-imidazol-3-ium bromide is an impurity of Ozagrel, an antiplatelet drug that acts as a thromboxane A2 synthesis inhibitor. Synonyms: (E)-3-(4-((1-(4-((E)-2-Carboxyvinyl)benzyl)-1H-imidazol-3-ium-3-yl)methyl)phenyl)acrylate; 883942-98-1. CAS No. 883942-98-1. Molecular formula: C23H21BrN2O4. Mole weight: 469.34.
(E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)-1-(1H-imidazol-1-yl)prop-2-en-1-one is an impurity of Ozagrel, an antiplatelet drug that acts as a thromboxane A2 synthesis inhibitor. Synonyms: (E)-3-(4-((1H-imidazol-1-yl)methyl)phenyl)-1-(1H-imidazol-1-yl)prop-2-en-1-one; 2452215-05-1. CAS No. 2452215-05-1. Molecular formula: C16H14N4O. Mole weight: 278.32.
methyl (E)-3-(4-(methoxymethyl)phenyl)acrylate
methyl (E)-3-(4-(methoxymethyl)phenyl)acrylate is an impurity of Ozagrel, an antiplatelet drug that acts as a thromboxane A2 synthesis inhibitor. Synonyms: methyl (E)-3-(4-(methoxymethyl)phenyl)acrylate; AKOS020185360; 121379-29-1. CAS No. 121379-29-1. Molecular formula: C12H14O3. Mole weight: 206.24.
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