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| Product | Description | |
|---|---|---|
| PAC-1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| PAC-1 | PAC-1. Group: Biochemicals. Alternative Names: 4-(Phenylmethyl)-1-piperazineacetic Acid (2E) -2- [ [2-Hydroxy-3- (2-propen-1-yl) phenyl] methylene] hydrazide. Grades: Highly Purified. CAS No. 1044929-62-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C23H28N4O2. US Biological Life Sciences. |  Worldwide |
| PAC-1 | PAC-1 is a procaspase-3 activator that induces apoptosis in cancer cells with an EC 50 of 2.08 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Procaspase activating compound 1. CAS No. 315183-21-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13523. |  |
| PAC-1 | PAC-1 is known as the first procaspase activating compound, which selectively induces apoptosis, or cell suicide, in cancerous cells. PAC-1 has shown good results in mouse models and is being further evaluated for use in humans. In 2010 a published study showed PAC-1 to be safe to research dogs, and a second study published later that same year reported that a PAC-1 derivative (called S-PAC-1) was well tolerated in a small Phase I Clinical Trial of pet dogs with lymphoma. Even at low doses of S-PAC-1, tumors regressed in 1/6 dogs, and the disease was stabilized (no additional tumor growth) in 3/6 dogs. Synonyms: 1-Piperazineacetic acid, 4-(phenylmethyl)-, 2-[[2-hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide; 1-Piperazineacetic acid, 4-(phenylmethyl)-, [[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide; PAC 1; PAC1; Procaspase activating compound 1. Grades: >98%. CAS No. 315183-21-2. Molecular formula: C23H28N4O2. Mole weight: 392.49. |  |
| PAC-113 | PAC-113 an anti-fungal, for the treatment of oral candidiasis infections. Molecular formula: C71H109N27O14. Mole weight: 1564.82. | |
| 1-Piperazineacetic Acid 2- [ [2-Hydroxy-3- (2-propen-1-yl) phenyl] methylene] hydrazide-d8 | 1-Piperazineacetic Acid 2- [ [2-Hydroxy-3- (2-propen-1-yl) phenyl] methylene] hydrazide-d8 is deuterium labelled 1-Piperazineacetic Acid 2- [ [2-Hydroxy-3- (2-propen-1-yl) phenyl] methylene] hydrazide (H953060) and has been employed to characterize the in vivo and in vitro metabolic profile of PAC-1 (P132000), an anti-tumor agent that induces apoptosis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. Molecular Formula: C16H14D8N4O2, Molecular Weight: 310.42. US Biological Life Sciences. | Worldwide |
| 4-Benzyl-1-piperazineacetic Acid-d8 Hydrazide | Isotope labelled 4-Benzyl-1-piperazineacetic Acid Hydrazide is an intermediate in the synthesis PAC-1 (P132000), a caspase 3 activator. Group: Biochemicals. Alternative Names: 4-(Phenylmethyl)-1-piperazineacetic Acid-d8 Hydrazide. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 4-Benzyl-1-piperazineacetic Acid Hydrazide | 4-Benzyl-1-piperazineacetic Acid Hydrazide is an intermediate in the synthesis PAC-1 (P132000), a caspase 3 activator. Group: Biochemicals. Alternative Names: 4-(Phenylmethyl)-1-piperazineacetic Acid Hydrazide. Grades: Highly Purified. CAS No. 24632-70-0. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| (4-Benzylpiperazin-1-yl)acetic Acid Ethyl Ester-d8 | (4-Benzylpiperazin-1-yl)acetic Acid Ethyl Ester-d8 is an isotope labelled intermediate in the synthesis of PAC-1-d8 (P132002), a caspase 3 activator. Group: Biochemicals. Alternative Names: Ethyl 2-(4-Benzylpiperazin-1-yl)acetate; Ethyl 4-Benzyl-1-piperazineacetate;4-Benzyl-1-piperazineacetic Acid Ethyl Ester; 4-(Phenylmethyl)-1-piperazineacetic Acid Ethyl Ester. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Asivatrep | Asivatrep (PAC-14028) is a potent and selective transient receptor potential vanilloid type I ( TRPV1 ) antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PAC-14028. CAS No. 1005168-10-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12777. | |
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