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| Product | Description | |
|---|---|---|
| PAF (C16) | PAF (C16). Group: Biochemicals. Grades: Purified. CAS No. 74389-68-7. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| PAF (C16) | PAF (C16) is an endogenous platelet-activating factor (PAF). It can induce increased vascular permeability. Synonyms: C16-02:0 PC; PC(16:0e/2:0); C16 PAF; 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine; PAF C-16. Grades: 98%. CAS No. 74389-68-7. Molecular formula: C26H54NO7P. Mole weight: 523.68. |  |
| C16-PAF | C16-PAF (PAF (C16)), a phospholipid mediator, is a platelet-activating factor and ligand for PAF G-protein-coupled receptor (PAFR). C16-PAF exhibits anti-apoptotic effect and inhibits caspase-dependent death by activating the PAFR. C16-PAF is a potent MAPK and MEK/ERK activator. C16-PAF induces increased vascular permeability[1][2][3][4][5]. Uses: Scientific research. Group: Natural products. Alternative Names: PAF (C16). CAS No. 74389-68-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108635. |  |
| 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine | 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PAF acether, Hag-PC, APRL, Hexadecyl-paf-acether, Platelet activating factor, AcGEPC, C16-PAF acether, HAGPC, HD-PAF, C16-PAF, Platelet-activating factor, Platelet-activating factor C16, P4904_SIGMA, P7568_SIGMA, P9525_SIGMA, Platelet Activating Factor-16, C26H54NO7P, PAF(C16), Blood platelet-activating factor, PAF (C16). Product Category: Heterocyclic Organic Compound. CAS No. 74389-68-7. Molecular formula: C26H54NO7P. Mole weight: 523.68. Purity: 0.96. IUPACName: [(2R)-2-acetyloxy-3-hexadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate. Product ID: ACM74389687. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 1-O-Hexadecyl-2-O-acetyl-sn-glycero-3-phosphocholine | 1-O-Hexadecyl-2-O-acetyl-sn-glycero-3-phosphocholine. Group: Biochemicals. Alternative Names: PAF (C16); Platelet activating factor (c16). Grades: Highly Purified. CAS No. 65154-06-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| Azelaoyl PAF | Azelaoyl-PAF is an alkyl phosphatidylcholine and is a component of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles, which contain low molecular weight species. It is a potent PPARγ agonist which competes for the thiazolidinedione binding site. Synonyms: 1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine; C16-09:0 (COOH) PC; 1-O-hexadecyl-2-nonadioyl-sn-glycero-3-phosphocholine; 1-O-Hexadecyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine. Grades: >99%. CAS No. 354583-69-0. Molecular formula: C33H66NO9P. Mole weight: 651.85. | |
| SKF-86002 | SKF-86002 is a p38 MAP kinase inhibitor, the IC50 is 0.1 - 1 μM. It potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes, the IC50 is1 μM. It also acts as an inhibitor of both cyclooxygenase (COX) and 5-lipoxygenase (5-LO). In vitro: SKF-86002 inhibited prostaglandin H2 synthase activity, the IC50 is 120 mM as well as prostanoid production by rat basophilic leukemia cells, the IC50 is mM and its sonicate ( the IC50 is 100 mM and human monocytes (the IC50 is 1 mM. It inhibited the generation of dihydroxyeicosatetraenoic acid and 5-hydroxyeicosatetraenoic acid by a high speed supernatant fraction of RBL-1 cells (the IC50 is 10 mM). It blocked superoxide anion production in response to FMLP and reduced adhesion and chemotaxis in response to PAF or FMLP. Uses: Skf-86002 could potently inhibit lps-induced il-1 and tnf-α production in human monocytes. it acts as an inhibitor of both cyclooxygenase and 5-lipoxygenase. Synonyms: SKF-86002; SKF 86002; SKF86002. 6-(4-fluorophenyl)-5-(4-pyridyl)-2,3-dihydroimidazo[2,1-b]-thiazole; 4-(4-Pyridyl)-5-(4-fluorophenyl)-2,3-dihydro-1-thia-3a,6-diazapentalene. Grades: >98%. CAS No. 72873-74-6. Molecular formula: C16H12FN3S. Mole weight: 297.36. | |
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