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| Product | Description | |
|---|---|---|
| Palovarotene | Palovarotene is a nuclear retinoic acid receptor γ ( RAR-γ ) agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R 667; Ro 3300074. CAS No. 410528-02-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14799. |  |
| Palovarotene | Palovarotene is a selective retinoic acid receptor gamma(RAR-γ) agonist for the treatment of emphysema. In small animal studies, palovarotene was claimed to reverse the structural, functional and inflammatory features of cigarette smoke-induced emphysema. Phase I clinical trials of palovarotene in patients with emphysema demonstrated that the drug is well tolerated, with improvements observed in markers of emphysema progression. Synonyms: 4-[(1E)-2-[5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-3-(1H-pyrazol-1-ylmethyl)-2-naphthalenyl]ethenyl]benzoic Acid; R 667; Ro 3300074; 4-{(E)-2-[5,5,8,8-Tetramethyl-3-(1H-pyrazol-1-ylmethyl)-5,6,7,8-tetrahydro-2-naphthalenyl]vinyl}benzoic acid; (E)-4-(2-(3-((1H-pyrazol-1-yl)methyl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic acid. Grades: 98%. CAS No. 410528-02-8. Molecular formula: C27H30N2O2. Mole weight: 414.54. |  |
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