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| Product | Description | |
|---|---|---|
| Parecoxib Impurity 1 | An impurity of Parecoxib. The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. Synonyms: Valdecoxib Disulfonamide Impurity; Parecoxib Impurity H. Grades: 95%. CAS No. 1708094-99-8. Molecular formula: C22H23N3O7S2. Mole weight: 505.56. |  |
| Parecoxib Impurity 10 | An impurity of Parecoxib which is a water-soluble and injectable prodrug of valdecoxib and a COX2 selective inhibitor. Grades: > 95%. Molecular formula: C16H12ClNO3S. Mole weight: 333.8. | |
| Parecoxib Impurity 11 | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: 4-(5-Methyl-4-phenylisoxazol-3-yl)benzenesulfonamide; 4-[5-Methyl-4-phenylisoxazol-3-yl]benzenesulfonamide; SCHEMBL6168344; BJYUOXUCQMUZRX-UHFFFAOYSA-N. Grades: > 95%. CAS No. 181696-12-8. Molecular formula: C16H14N2O3S. Mole weight: 314.37. | |
| Parecoxib Impurity 24 | An impurity of Parecoxib. The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. Synonyms: N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)isobutyramide; 2-methyl-N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonylpropanamide; Propanamide, 2-methyl-N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-; SCHEMBL5069872; DTXSID50627261; AS-80624; CS-0255351; F83303; 2-Methyl-N-[[4- (5-methyl-3-phenyl-4-isoxazolyl) phenyl]sulfonyl]propanamide; 2-Methyl-N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sulfonyl]propanamide; 2-METHYL-N-[4-(5-METHYL-3-PHENYL-1,2-OXAZOL-4-YL)BENZENESULFONYL]PROPANAMIDE; N-((4-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)isobutyramide (Palbociclib Impurity). Grades: 95%. CAS No. 198470-82-5. Molecular formula: C20H20N2O4S. Mole weight: 384.45. | |
| Parecoxib Impurity 3 | An impurity of Parecoxib which is a COX2 selective inhibitor. Grades: > 95%. Molecular formula: C16H14N2O3S. Mole weight: 314.37. | |
| Parecoxib Impurity 4 | Cas No. 181695-72-7. | |
| Parecoxib Impurity 6 Sodium Salt | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Grades: > 95%. CAS No. 198470-92-7. Molecular formula: C20H19N2O4S.Na. Mole weight: 406.44. | |
| Parecoxib Impurity 7 | An impurity of Parecoxib which is an injectable pro drug of valdecoxib and a COX2 selective inhibitor. Synonyms: Benzenesulfonamide, N-hydroxy-4-(5-methyl-3-phenyl-4-isoxazolyl)-; UNII-6M6L09OU0A; Valdecoxib metabolite M2; N-hydroxy-4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide; 6M6L09OU0A; n-hydroxy-4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide; CHEMBL254418; SCHEMBL5481289; CHEMBL1182611; DTXSID30458535; BDBM50229774; PD119532; Q27265142; N-hydroxy-4-(5-methyl-3-phenyl-4-isoxazolyl)-benzenesulfonamide; N-hydroxy-4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide hydrate; N-Hydroxy-4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide monohydrate. Grades: > 95%. CAS No. 501093-49-8. Molecular formula: C16H14N2O4S. Mole weight: 330.36. | |
| Parecoxib Impurity 9 | An impurity of Parecoxib which is a COX2 selective inhibitor. Grades: > 95%. Molecular formula: C17H18N2O4S. Mole weight: 346.41. | |
| Parecoxib Impurity D | An impurity of Parecoxib which is a water-soluble and injectable prodrug of valdecoxib and a COX2 selective inhibitor. Grades: > 95%. Molecular formula: C16H14N2O3S. Mole weight: 314.37. | |
| Parecoxib Impurity E | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Grades: > 95%. Molecular formula: C19H17N2O4S.Na. Mole weight: 392.41. | |
| Parecoxib Impurity HSJZ | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Grades: ≥95%. Molecular formula: C17H15NO4S. Mole weight: 329.37. | |
| Parecoxib Impurity HSYBZ | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Grades: ≥95%. Molecular formula: C19H19NO4S. Mole weight: 357.42. | |
| 2-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Benzenesulfonamide, 2-(5-methyl-3-phenyl-4-isoxazolyl)-; Parecoxib Impurity 48. CAS No. 2304623-35-4. Molecular formula: C16H14N2O3S. Mole weight: 314.36. | |
| 2-(5-methyl-4-phenylisoxazol-3-yl)benzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 37. CAS No. 2304623-37-6. Molecular formula: C16H14N2O3S. Mole weight: 314.36. | |
| 3-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 09. CAS No. 386273-25-2. Molecular formula: C16H14N2O3S. Mole weight: 314.36. | |
| 3-methyl-4,5-diphenylisoxazole | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 38. CAS No. 75115-00-3. Molecular formula: C16H13NO. Mole weight: 235.28. | |
| 4-(3-methyl-4-phenylisoxazol-5-yl)benzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 39; Benzenesulfonamide, 4-(3-methyl-5-phenyl-4-isoxazolyl)-. Grades: 98%. CAS No. 181695-84-1. Molecular formula: C16H14N2O3S. Mole weight: 314.36. | |
| 4,4'-(5-methylisoxazole-3,4-diyl)dibenzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 15; Valdecoxib Impurity 13. CAS No. 2251048-58-3. Molecular formula: C16H15N3O5S2. Mole weight: 393.43. | |
| 4-(4-chlorophenyl)-5-methyl-3-phenylisoxazole | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 40. CAS No. 1448355-87-0. Molecular formula: C16H12ClNO. Mole weight: 269.72. | |
| 4,4'-(sulfonylbis(4,1-phenylene))bis(5-methyl-3-phenylisoxazole) | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 29. CAS No. 2338845-31-9. Molecular formula: C32H24N2O4S. Mole weight: 532.61. | |
| 4-(5-methyl-2-phenyloxazol-4-yl)benzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 47. Grades: >95%. CAS No. 2242749-01-3. Molecular formula: C16H14N2O3S. Mole weight: 314.36. | |
| ethyl 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonate | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Benzenesulfonic acid, 4-(5-methyl-3-phenyl-4-isoxazolyl)-, ethyl ester; Parecoxib Impurity 27. Grades: >95%. CAS No. 1884279-18-8. Molecular formula: C18H17NO4S. Mole weight: 343.40. | |
| N-((2-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)propionamide | N-((2-(5-Methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)propionamide is an impurity of Parecoxib, which is a selective COX2 inhibitor and a water-soluble and injectable prodrug of valdecoxib. Uses: Cyclooxygenase 2 inhibitors. Synonyms: Propanamide, N-[[2-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
| N-((2-(5-methyl-4-phenylisoxazol-3-yl)phenyl)sulfonyl)propionamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 34. CAS No. 2304623-38-7. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
| N-[[3- (5-Methyl-3-phenyl-4-isoxazolyl) phenyl]sulfonyl]propanamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Sodium Impurity 14; Propanamide, N-[[3-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-. Grades: ≥95%. CAS No. 1709956-89-7. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
| N-((3-(5-methyl-4-phenylisoxazol-3-yl)phenyl)sulfonyl)propionamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 20. CAS No. 2229657-81-0. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
| N-((4-(3-methyl-5-phenylisoxazol-4-yl)phenyl)sulfonyl)propionamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Propanamide, N-[[4-(3-methyl-5-phenyl-4-isoxazolyl)phenyl]sulfonyl]-; Parecoxib Impurity 42. Grades: 98%. CAS No. 477594-28-8. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
| N-[[4- (5-Methyl-3-phenyl-4-isoxazolyl) phenyl]sulfonyl]butanamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Butanamide, N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-; Parecoxib Impurity H. Grades: ≥95%. CAS No. 198470-91-6. Molecular formula: C20H20N2O4S. Mole weight: 384.45. | |
| N-((4-(5-methyl-4-phenylisoxazol-3-yl)phenyl)sulfonyl)propionamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Propanamide, N-[[4-(5-methyl-4-phenyl-3-isoxazolyl)phenyl]sulfonyl]-; Parecoxib Impurity 21. CAS No. 2235371-89-6. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
| N-ethyl-4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Benzenesulfonamide, N-ethyl-4-(5-methyl-3-phenyl-4-isoxazolyl)-; Parecoxib Impurity 28. CAS No. 473465-11-1. Molecular formula: C18H18N2O3S. Mole weight: 342.41. | |
| N,N'-((5-methylisoxazole-3,4-diyl)bis(4,1-phenylenesulfonyl))dipropionamide | An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 25. CAS No. 2251048-76-5. Molecular formula: C22H23N3O7S2. Mole weight: 505.56. | |
| Parecoxib N-Oxide | An impurity of Parecoxib which is an injectable pro drug of valdecoxib and a COX2 selective inhibitor. Grades: > 95%. Molecular formula: C19H18N2O5S. Mole weight: 386.43. | |
| Valdecoxib Disulfonamide Impurity | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: Parecoxib Impurity 1. Molecular formula: C22H23N3O7S2. Mole weight: 505.57. | |
| Valdecoxib Impurity D | Valdecoxib Impurity D is a metabolite of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: Parecoxib Impurity 8; Valdecoxib Sulfonic Acid; 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonic Acid. CAS No. 181696-35-5. Molecular formula: C16H13NO4S. Mole weight: 315.35. | |
| Valdecoxib m-Sulfonamide Impurity | An impurity of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Synonyms: Parecoxib Impurity 2. Molecular formula: C19H18N2O4S. Mole weight: 370.43. | |
| Valdecoxib Impurity J | The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. Uses: Cyclooxygenase 2 inhibitors. Synonyms: SC 69124; SC69124; SC-69124; Valus-P; Vorth-P. Grades: >98%. CAS No. 198470-84-7. Molecular formula: C19H18N2O4S. Mole weight: 370.42. | |
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