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| Product | Description | |
|---|---|---|
| Paromamine | Paromamine is a disaccharide portion common to several aminoglycoside antibiotics that are susceptible to enzymic phosphorylation, into its 3'epimer. Synonyms: 4-O-(2-Amino-2-deoxy-alpha-D-glucopyranosyl)-2-deoxy-D-streptamine; (2R,3S,4R,5R,6S)-5-Amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-2-(hydroxymethyl)oxane-3,4-diol. Grades: > 95%. CAS No. 534-47-4. Molecular formula: C12H25N3O7. Mole weight: 323.34. |  |
| paromamine 6'-oxidase | Contains FAD. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Works in combination with EC 2.6.1.93, neamine transaminase, to replace the 6'-hydroxy group of paromamine with an amino group. The enzyme from the bacterium Streptomyces fradiae also catalyses EC 1.1.3.44, 6'''-hydroxyneomycin C oxidase. Group: Enzymes. Synonyms: btrQ (gene name); neoG (gene name); kanI (gene name); tacB (gene name); neoQ (obsolete gene name). Enzyme Commission Number: EC 1.1.3.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0416; paromamine 6'-oxidase; EC 1.1.3.43; btrQ (gene name); neoG (gene name); kanI (gene name); tacB (gene name); neoQ (obsolete gene name). Cat No: EXWM-0416. |  |
| Paromamine trihydrochloride | Paromamine trihydrochloride is a robust antibiotic product employed for the research purpose of bacterial infections, exerting its antimicrobial prowess by impeding the synthesis of bacterial proteins through its affinitive binding to the ribosome. This compound is used to study a myriad of pathogens encompassing both Gram-positive and Gram-negative bacterial strains. Synonyms: (2R,3S,4R,5R,6S)-5-amino-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy-2-(hydroxymethyl)oxane-3,4-diol trihydrochloride. CAS No. 18685-97-7. Molecular formula: C12H25N3O7ยท3HCl. Mole weight: 432.72. | |
| 5-O-(5-Amino-5-deoxy-a-D-ribofuranosyl)-1-N-[(S)-4-amino-2-hydroxy-butanoyl]paromamine | | |
| 5-O-(5-Amino-5-deoxy-b-D-ribofuranosyl)-1-N-[(S)-4-amino-2-hydroxy-butanoyl]paromamine | | |
| 6'''-hydroxyneomycin C oxidase | Contains FAD. Involved in the biosynthetic pathway of aminoglycoside antibiotics of the neomycin family. Works in combination with EC 2.6.1.95, neomycin C transaminase, to replace the 6'''-hydroxy group of 6'''-hydroxyneomycin C with an amino group.Also catalyses EC 1.1.3.43, paromamine 6'-oxidase. Group: Enzymes. Synonyms: neoG (gene name); neoQ (obsolete gene name). Enzyme Commission Number: EC 1.1.3.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0417; 6'''-hydroxyneomycin C oxidase; EC 1.1.3.44; neoG (gene name); neoQ (obsolete gene name). Cat No: EXWM-0417. | |
| kanamycin kinase | Also acts on the antibiotics neomycin, paromomycin, neamine, paromamine, vistamycin and gentamicin A. An enzyme from Pseudomonas aeruginosa also acts on butirosin. Group: Enzymes. Synonyms: neomycin-kanamycin phosphotransferase. Enzyme Commission Number: EC 2.7.1.95. CAS No. 62213-36-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3125; kanamycin kinase; EC 2.7.1.95; 62213-36-9; neomycin-kanamycin phosphotransferase. Cat No: EXWM-3125. | |
| neamine transaminase | The reaction occurs in vivo in the opposite direction. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin B, butirosin, neomycin and ribostamycin. Works in combination with EC 1.1.3.43, paromamine 6-oxidase, to replace the 6'-hydroxy group of paromamine with an amino group. The enzyme from the bacterium Streptomyces kanamyceticus can also catalyse EC 2.6.1.94, 2'-deamino-2'-hydroxyneamine transaminase, which leads to production of kanamycin A. The enzyme from the bacterium Streptomyces fradiae can also catalyse EC 2.6.1.95, leading to production of neomycin C. Group: Enzymes. Synonyms: glutamate-6'-dehydroparomamine aminotransferase; btrB (gene name); neoN (gene name); kacL (gene name). Enzyme Commission Number: EC 2.6.1.93. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2934; neamine transaminase; EC 2.6.1.93; glutamate-6'-dehydroparomamine aminotransferase; btrB (gene name); neoN (gene name); kacL (gene name). Cat No: EXWM-2934. | |
| Neomycin Sulfate EP Impurity C | An impurity of Neomycin, which is an aminoglycoside antibiotic found in many topical medications. Synonyms: 4-O-(2-amino-2-deoxy-d-glucopyranosyl)-2-deoxy-d-streptamine (paromamine or neomycin D). Grades: > 95%. Molecular formula: C23H46N6O13. Mole weight: 614.66. | |
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