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| Product | Description | |
|---|---|---|
| PCI-34051 | PCI-34051 is a potent and selective HDAC8 inhibitor with IC 50 of 10 nM, with >200-fold selectivity over the other HDAC isoforms. Uses: Scientific research. Group: Signaling pathways. CAS No. 950762-95-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15224. |  |
| PCI-34051 | PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias. PCI-34051 did not affect other hematopoietic or solid tumor lines. PCI-34051 treatment has been shown to significantly reduce cholesterol accumulation in Niemann-Pick type C1 gene mutated human fibroblast. Group: Biochemicals. Alternative Names: N-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide; PCI 34051. Grades: Highly Purified. CAS No. 950762-95-5. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| PCI-34051 | PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor with >200-fold selectivity over the other HDAC isoforms. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias, but not in other hematopoietic or solid tumor lines. Unlike broad-spectrum HDAC inhibitors, PCI-34051 does not cause detectable histone or tubulin acetylation. PCI-34051 could offer benefits including a greater therapeutic index for treating T-cell malignancies. Synonyms: PCI-34051; PCI 34051; PCI34051. Grades: 0.98. CAS No. 950762-95-5. Molecular formula: C17H16N2O3. Mole weight: 296.326. |  |
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