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PCI-34051 PCI-34051 is a potent and selective HDAC8 inhibitor with IC 50 of 10 nM, with >200-fold selectivity over the other HDAC isoforms. Uses: Scientific research. Group: Signaling pathways. CAS No. 950762-95-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15224. MedChemExpress MCE
PCI-34051 PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias. PCI-34051 did not affect other hematopoietic or solid tumor lines. PCI-34051 treatment has been shown to significantly reduce cholesterol accumulation in Niemann-Pick type C1 gene mutated human fibroblast. Group: Biochemicals. Alternative Names: N-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide; PCI 34051. Grades: Highly Purified. CAS No. 950762-95-5. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
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