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2,2,3,3,3-Pentafluoropropylamine is used to prepare fluorinated diphenyl pyridyl ethanamine-based cholesteryl ester transfer protein inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 374-14-1. Pack Sizes: 2.5g, 25g. Molecular Formula: C3H5ClF5N, Molecular Weight: 185.52. US Biological Life Sciences.
Poly(2,2,3,3,3-pentafluoropropyl methacrylate-co-glycidyl methacrylate). Group: other materials.
RO4929097
RO4929097, a small-molecule inhibitor of γ secretase (IC50 = 4 nM, EC50 = 5 nM), inhibits cellular processing of Aβ40 (EC50 = 14 nM) and Notch (EC50 = 5 nM). It was shown to decrease the levels of Notch transcriptional target HES1 in human primary melanoma cell lines. Uses: Enzyme inhibitors. Synonyms: RO-4929097; 2,2-dimethyl-N-[(7S)-6-oxo-5,7-dihydrobenzo[d][1]benzazepin-7-yl]-N'-(2,2,3,3,3-pentafluoropropyl)propanediamide. Grades: >98%. CAS No. 847925-91-1. Molecular formula: C22H20F5N3O3. Mole weight: 469.4.
RO4929097
RO4929097 is a γ secretase inhibitor with IC50 of 4 nM in a cell-free assay, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively and in Phase 2. Group: Fluorinated apis. CAS No. 847925-91-1. Molecular formula: C22H20F5N3O3. Mole weight: 469.4. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: 2,2-dimethyl-N-[(7S)-6-oxo-5,7-dihydrobenzo[d][1]benzazepin-7-yl]-N'-(2,2,3,3,3-pentafluoropropyl)propanediamide. Catalog: OFC847925911.
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