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Pentalenic acid is a sesquiterpenoid originally isolated from S. avermitilis. It is a precursor in the biosynthesis of the antibiotic pentalenolactone. Synonyms: 69394-19-0; 9-Hydroxy-2,10,10-trimethyltricyclo[6.3.0.01,5]undec-6-ene-6-carboxylic acid; BS-1324MCULE-6511007969; NCGC00381256-01. Grades: >95% by HPLC. CAS No. 69394-19-0. Molecular formula: C15H22O3. Mole weight: 250.33.
pentalenic acid synthase
A heme-thiolate enzyme (P-450). Isolated from the bacterium Streptomyces avermitilis. The product, pentalenate, is a co-metabolite from pentalenolactone biosynthesis. Group: Enzymes. Synonyms: CYP105D7; sav7469 (gene name); 1-deoxypentalenate,reduced ferredoxin:O2 oxidoreductase. Enzyme Commission Number: EC 1.14.15.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0936; pentalenic acid synthase; EC 1.14.15.11; CYP105D7; sav7469 (gene name); 1-deoxypentalenate,reduced ferredoxin:O2 oxidoreductase. Cat No: EXWM-0936.
1-deoxypentalenic acid 11β-hydroxylase
The enzyme requires Fe(II) and ascorbate. Isolated from the bacterium Streptomyces avermitilis. Part of the pathway for pentalenolactone biosynthesis. Group: Enzymes. Synonyms: ptlH (gene name); sav2991 (gene name); pntH (gene name). Enzyme Commission Number: EC 1.14.11.35. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0653; 1-deoxypentalenic acid 11β-hydroxylase; EC 1.14.11.35; ptlH (gene name); sav2991 (gene name); pntH (gene name). Cat No: EXWM-0653.
1-deoxy-11β-hydroxypentalenate dehydrogenase
Isolated from the bacterium Streptomyces avermitilis and present in many other Streptomyces species. Part of the pathway for pentalenolactone biosynthesis. Group: Enzymes. Synonyms: 1-deoxy-11β-hydroxypentalenic acid dehydrogenase; ptlF (gene name); penF (gene name). Enzyme Commission Number: EC 1.1.1.340. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0255; 1-deoxy-11β-hydroxypentalenate dehydrogenase; EC 1.1.1.340; 1-deoxy-11β-hydroxypentalenic acid dehydrogenase; ptlF (gene name); penF (gene name). Cat No: EXWM-0255.
16(R)-Iloprost
Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Synonyms: Iloprost R-isomer; (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S,4R)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid. Grades: ≥98%. CAS No. 74843-13-3. Molecular formula: C22H32O4. Mole weight: 360.5.
16(S)-Iloprost
Iloprost is a second generation structural analog of prostacyclin (PGI2) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Synonyms: Iloprost S-isomer; (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S,4S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid. Grades: ≥98%. CAS No. 74843-14-4. Molecular formula: C22H32O4. Mole weight: 360.5.
AA-57
AA-57 is an acidic lipophilic antibiotic produced by Streptomyces sp. AA-57. It has anti-gram-positive bacteria, negative bacteria and mycobacterial activity. Synonyms: AA-57; Pentaleno(1,6a-c)pyran-5-carboxylic acid, 1-(chloromethyl)-1,2,4,4a,6a,7-hexahydro-1-hydroxy-7,8-dimethyl-2-oxo-, (1S-(1alpha,4aalpha,6abeta,7alpha,9aR*))-; Pentaleno(1,3a-c)pyran-5-carboxylic acid, 1,2,4,4a,6a,7-hexadyro-1-(chloromethyl)-7,8-dimethyl-1-hydroxy-2-oxo-. Grades: >98%. CAS No. 68026-87-9. Molecular formula: C15H17ClO5. Mole weight: 312.74.
Recombinant human IL - 2; Interleukin-2 is a secreted cytokine, also called IL-2. Aldesleukin (IL-2 made in the laboratory) is being used as a biological response modifier to boost the immune system in cancer therapy. Synonyms: Iloprost R-isomer; 74843-13-3; 16(R)-Iloprost; 16-(R)-Iloprost; UNII-AHG2128QW6; AHG2128QW6; (5E)-5-((3aS,4R,5R,6aS)-5-Hydroxy-4-((1E,3S,4R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl)hexahydropentalen-2(1H)-ylidene)pentanoic acid; (5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(E,3S,4R)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid; Pentanoic acid, 5-((3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-((1E,3S,4R)-3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene)-, (5E)-; (5e)-5-[(3as,4r,5r,6as)-5-Hydroxy-4-[(1e,3s,4r)-3-Hydroxy-4-Methyloct-1-En-6-Yn-1-Yl]hexahydropentalen-2(1h)-Ylidene]pentanoic Acid; IL2; SCHEMBL21509107; AKOS040755122; PD021248; Q27273925; 5-((3AS,4R,5R,6aS,E)-5-hydroxy-4-((3S,4R,E)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl)hexahydropentalen-2(1H)-ylidene)pentanoic acid. Molecular formula: C22H32O4. Mole weight: 360.5.
Iloprost is a drug used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and other diseases in which the blood vessels are constricted and blood can't flow to the tissues. Synonyms: Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]-, (5E)-; (5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic acid; Pentanoic acid, 5-[(3aS,4R,5R,6aS)-hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]-, (5E)-; (1S,2R,3R,5S)-7-[(E)-4-Carboxybutylidene]-2-[(3S,1E)-3-hydroxy-4-methyl-6-octyn-1-enyl]-bicyclo[3.3.0]octane; Ciloprost; Endoprost; Ilomedin; ZK 36374. Grades: 98%. CAS No. 78919-13-8. Molecular formula: C22H32O4. Mole weight: 360.49.
Retigeranic acid A
Retigeranic acid A is a representative member of the sesterterpenoid family of compounds and exhibits a broad range of biological activities. Synonyms: (-)-Retigeranic acid A; Retigeranic acid; (3R, 11aS)-2, 3, 3aβ, 4, 5, 5a, 5bα, 6, 6a, 7, 8, 9, 9aβ, 10-Tetradecahydro-3β, 5aα, 6aα-trimethyl-9β-isopropyl-1H-pentaleno[1, 6a-a]-s-indacene-11-carboxylic acid. CAS No. 40184-98-3. Molecular formula: C25H38O2. Mole weight: 370.57.
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