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| Product | Description | |
|---|---|---|
| PF 429242 | PF 429242 is a reversible, competitive, cell permeable inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM) without disrupting a panel of serine proteases. Some studies reported that the inhibition of SKI-1/S1P, a master lipo- 387 genic regulator, could impair HCV genome replication, lipid droplet 388 homeostasis and the production of infectious HCV virions. Synonyms: PF-429242; PF 429242; PF429242. Benzamide, 4-[(diethylamino)?methyl]?-N-[2-(2-methoxyphenyl)?ethyl]?-N-(3R)?-3-pyrrolidinyl-; 4-[(Diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinylbenzamide. CAS No. 947303-87-9. Molecular formula: C25H35N3O2. Mole weight: 409.56. |  |
| PF 429242 dihydrochloride | PF 429242 is a reversible and competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM), a transcriptional regulators of cholesterol, fatty acid, and glucose metabolism. It reduces hepatic synthesis of cholesterol and fatty acid in mice. Synonyms: PF-429242 dihydrochloride; PF429242 dihydrochloride. Grades: ≥97% by HPLC. CAS No. 2248666-66-0. Molecular formula: C25H35N3O2ยท2HCl. Mole weight: 482.49. | |
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