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PF 750 Fatty acid amide hydrolase (FAAH) inhibitor, selectively inhibiting FAAH within the central nervous system. Group: Biochemicals. Alternative Names: N-Phenyl-4-(3-quinolinylmethyl)-1-piperidinecarboxamide; N-Phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide. Grades: Highly Purified. CAS No. 959151-50-9. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
PF 750 PF 750 is a potent, time-dependent, irreversible FAAH inhibitor (IC50 = 16.2 nM) that exhibits no activity at a range of other serine hydrolases. Activity-based profiling of various human and murine tissue proteome samples revealed that PF-750 is highly selective for FAAH relative to other serine hydrolases, showing no discernable off-site activity up to 500 μM. Synonyms: PF-750; PF 750; PF750. N-Phenyl-4-(3-quinolinylmethyl)-1-piperidinecarboxamide. Grades: ≥98% by HPLC. CAS No. 959151-50-9. Molecular formula: C22H23N3O. Mole weight: 345.44. BOC Sciences 10
Poly(ethylene glycol), 16 acetylene dendron, generation 3 Dendrimers and dendrons are symmetrically branched polymer structures that possess a well-defined spatial distribution of functional groups. Dendrimers are chemically modified by attaching poly ethylene glycol (PEG) molecule to increase its solubility and prolong circulation half-life."Clickable groups", such as primary acetylenes, are introduced to the mono dispersed dendritic structures, using "click" chemistry. These acetylene groups, attached to Bis-MPA based dendrons, allow it to form the conjugates with bioactive moieties such as carbohydrate, fluorescent dyes, disaccharides etc. Uses: The proposed uses are: as an efficient drug delivery system. in vitro toxicological studies; in vivo via radionuclide labeling and optical imaging biosensors;dip pen nanolithography. Group: Dendrimers. Alternative Names: PFD-G3-PEG6k-Acetylene, Dendron functionalized PEG acetylene, generation 3, Bis[2,2-bis(hydroxymethyl)propanoic acid] PEG, PEG-6000, Bis-MPA poly(ethylene glycol). Pack Sizes: Packaging 500 mg in glass insert. Molecular formula: PEG average Mn 6000 (n~130, esterified with 16 acetylene groups) Mn 7500-9500 (by NMR) average Mn 8000. Alfa Chemistry Materials 5
Ro 90-7501 Ro 90-7501, under the IUPCA name 2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine, a type of aminoquinolines, is an inhibitor of Aβ42 fibril assembly so that can reduce Aβ42-induced toxicity (EC50 = 2 μM). Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: RO 90-7501; RO 90 7501; RO 907501; RO907501; RO-90-7501; 2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine; Ro 90-7501; 293762-45-5; GNF-Pf-5510; STK367782; CBChromo1_000149; AC1LGN68; Cambridge id 5180073; CBDivE_006377; R0529_SIGMA; CHEMBL578741; SCHEMBL10002475; STOCK2S-20922; CTK8E9490; DTXSID80356431; HMS3262E21; HMS3269A19; Tox21_500670; ZINC18206988; AKOS000635167; AKOS001483260; CCG-221974; LP00670; MCULE-7528949788; NCGC00094031-06; NCGC00261355-01; BAS 03420670; HE063215; HE332505; ST078196; AB00074940-01; AG-690/09405007; BRD-K58299615-001-02-7; 3B1-004024; 2'-(4-aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine; 2'-(4-aminophenyl)-1H,1'H-2,5'-bibenzimidazol-5-amine; 2-[2-(4-aminophenyl)benzimidazol-6-yl]benzimidazole-6-ylamine; 2'-(4-Amino-phenyl)-3H,3'H-[2,5']bibenzoimidazolyl-5-ylamine; 2-[2-(4-aminophenyl)-3H-benzimidazol-5-yl]-3H-benzimidazol-5-amine; Ro 90-7501|2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine; 2-[2-(4-aminophenyl)-1H-1,3-benzodiazol-6-yl]-1H-1,3-benzodiazol-6-amine; 2-[2-(4-AMINOPHENYL)-3H-1,3-BENZODIAZOL-5-YL]-3H-1,3-BENZODIAZOL-5-AMINE. CAS No. 293762-45-5. Molecular formula: C20H16N6. Mole weight: 340.39. BOC Sciences 10

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