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| Product | Description | |
|---|---|---|
| PF-07321332 | Nirmatrelvir, also known as PF-07321332 (brand name: Paxlovid), is an orally bioavailable 3C-like protease (3CLPRO) inhibitor and SARS-CoV-2 Mpro inhibitor. This drug is being investigated for safety, tolerability, and pharmacokinetics before moving on to studies of efficacy in the treatment or prophylaxis of COVID-19. 3CLPRO is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2. PF-07321332 is an oral COVID-19 antiviral clinical candidate. By inhibiting the main protease, PF-07321332 prevents the virus from cleaving long protein chains into the parts it needs to reproduce itself. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Nirmatrelvir; PF-07321332; PF 07321332; PF07321332; brand name Paxlovid. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2628280-40-8. Molecular formula: C23H32F3N5O4. Mole weight: 499.54. Purity: >98%. IUPACName: (1R,2S,5S)-N-((S)-1-cyano-2-((S)-2-oxopyrrolidin-3-yl)ethyl)-3-((S)-3,3-dimethyl-2-(2,2,2-trifluoroacetamido)butanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide. Canonical SMILES: [H][C@]12CN([C@H](C(=O)N[C@@H](C[C@]3([H])CCNC3=O)C#N)[C@@]1([H])C2(C)C)C(=O)[C@@H](NC(=O)C(F)(F)F)C(C)(C)C. Product ID: ACM2628280408. Alfa Chemistry ISO 9001:2015 Certified. |  |
| PF-07321332 | PF-07321332 is an orally available SARS-CoV 3C-like protease (3CLPRO) inhibitor. 3C-like protease (3CLPRO) is the main protease found in coronaviruses, which cleaves the coronavirus polyprotein at eleven conserved sites. PF-07321332 has demonstrated oral activity in a mouse-adapted SARS-CoV-2 model and has achieved oral plasma concentrations exceeding the in vitro antiviral cell potency in a phase I clinical trial in healthy human participants. Synonyms: PF 07321332; PF07321332. Grades: 98%. CAS No. 2628280-40-8. Molecular formula: C23H32F3N5O4. Mole weight: 499.53. |  |
| Nirmatrelvir | Nirmatrelvir (PF-07321332) is a potent and orally active SARS-CoV 3C-like protease (3CL PRO ) inhibitor. Nirmatrelvir (PF-07321332) targets to the SARS-CoV-2 virus and can be used for COVID-19 research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-07321332. CAS No. 2628280-40-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-138687. |  |
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