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| Product | Description | |
|---|---|---|
| PHA-543613 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| PHA-543613 | PHA-543613 is a potent, orally active, brain-penetrant and selective α7 nAChR agonist with a K i of 8.8 nM. PHA-543613 displays selectivity for α7-nAChR over α3β4, α1β1γδ, α4β2 and 5-HT3 receptors [1]. PHA-543613 can be used for the cognitive deficits of Alzheimer's disease and schizophrenia research [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 478149-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105670. |  |
| PHA-543613 Dihydrochloride | PHA-543613 is a potent selective α7 nAChR agonist. Nicotinic acetylcholine receptors are ligand-gated ion channels activated by nicotine, expressed in multiple tissues, with high functional expression in brain. The homomeric subtype α7 is a potential therapeutic target for cognitive deficits in schizophrenia and Alzheimer?s disease. PHA-543613 is active in both in vitro (binding, calcium flux, patch-clamp) and in vivo (auditory gating, novel object recognition) assays. Group: Biochemicals. Alternative Names: N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide Dihydrochloride;PHA 543613E. Grades: Highly Purified. CAS No. 478148-58-2. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| PHA-543,613 (N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, Alpha 7 Nicotinic Acetylcholine Receptor (alpha7 nAChR) Agonist, PHA-543613) | A potent agonist highly selective for alpha7 nicotinic acetylcholine receptor (alpha7 nAChR). Bioavaible admitted orally. Widely used in studies of the functional roles of alpha7 nAChR in learning and memory, sensory gating, and cognitive functions as well as Schizophrenia and Alzheimer's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 478149-53-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-furo[2,3-c]pyridine-5-carboxamide hydrochloride | N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-furo[2,3-c]pyridine-5-carboxamide hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PHA 543613 HYDROCHLORIDE, 478149-53-0, CTK8E9850. Product Category: Heterocyclic Organic Compound. CAS No. 478149-53-0. Molecular formula: 307.78. Purity: >98 %. IUPACName: N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]furo[2,3-c]pyridine-5-carboxamide;hydrochloride. Canonical SMILES: C1CN2CCC1C(C2)NC(=O)C3=NC=C4C(=C3)C=CO4.Cl. Product ID: ACM478149530. Alfa Chemistry ISO 9001:2015 Certified. Categories: PHA-543613 hydrochloride. |  |
| PHA 543613 dihydrochloride | PHA 543613 dihydrochloride is a potent and selective α7 nicotinic acetylcholine receptor (nAChR) agonist with rapid brain penetration and high oral bioavailability. PHA 543613 is potentially used for the treatment of cognitive deficits in schizophrenia. Uses: Potential treatment of cognitive deficits in schizophrenia. Synonyms: PHA 543613 dihydrochloride; PHA543613 dihydrochloride; PHA-543613 dihydrochloride; N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]furo[2,3-c]pyridine-5-carboxamide dihydrochloride. Grades: 99%. CAS No. 478148-58-2. Molecular formula: C15H17N3O2.2HCl. Mole weight: 344.24. |  |
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