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| Product | Description | |
|---|---|---|
| PHA-767491 | PHA-767491 is a potent, ATP-competitive dual cdc7/cdk9 inhibitor (IC50 values are 10 and 34 nM respectively) that prevents initiation of DNA replication. Synonyms: PHA-767491; PHA767491; PHA 767491. CAS No. 845714-00-3. Molecular formula: C12H11N3O. Mole weight: 213.24. |  |
| PHA-767491 hydrochloride | PHA-767491 hydrochloride is a potent, ATP-competitive dual Cdc7/Cdk9 inhibitor, which prevents initiation of DNA replication. It inhibits cell proliferation in a variety of human cell lines and induces apoptosis in a p53-independent manner in vivo. It also inhibits mitogen-activated protein kinase-activated protein kinase-2 (MK2). Synonyms: CAY-10572 hydrochloride; PHA-767491 hydrochloride; CAY 10572 hydrochloride; PHA 767491 hydrochloride; CAY10572 hydrochloride; PHA767491 hydrochloride. Grades: >98%. CAS No. 942425-68-5. Molecular formula: C12H12ClN3O. Mole weight: 249.7. | |
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