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| Product | Description | |
|---|---|---|
| Phenamil | Phenamil, a second generation analog of amiloride (hydrochloride), inhibits TRPP3-mediated currents (IC50 = 0.14 μM) and also inhibits epithelial Na+ channels (Kd = 0.4 nM for a high affinity site on the epithelial Na+ channel). Synonyms: 2-Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-; 3,5-Diamino-6-chloro-N-[imino(phenylamino)methyl]-2-pyrazinecarboxamide; Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-(phenylamidino)-; Pyrazinecarboxamide, 3,5-diamino-6-chloro-N-[imino(phenylamino)methyl]-; Phenylamil; 3,5-diamino-6-chloro-N-(N-phenylcarbamimidoyl)pyrazine-2-carboxamide; 3, 5-Diamino-6-chloro-N-[imino (phenylamino) methyl]pyrazinecarboxamide. Grades: ≥95%. CAS No. 2038-35-9. Molecular formula: C12H12ClN7O. Mole weight: 305.72. |  |
| Phenamil | Phenamil. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PHENAMIL;3,5-DIAMINO-6-CHLORO-N-[IMINO(PHENYLAMINO)METHYL]-PYRAZINECAR-BOXAMIDE;3,5-diamino-6-chloro-n-[imino(phenylamino)methyl]pyrazinecarboxamide methanesulfonate salt;phenamil methanesulfonate salt;phenylamil;3,5-Diamino-6-chloro-N-[imino(phenylamino. Product Category: Heterocyclic Organic Compound. Appearance: Off-white to yellow solid. CAS No. 2038-35-9. Molecular formula: C12H12ClN7O. Mole weight: 305.72. Product ID: ACM2038359. Alfa Chemistry ISO 9001:2015 Certified. Categories: Phenamidine. |  |
| Phenamil (3,5-Diamino-6-chloro-N-[imino(pheny lamino) methyl] pyrazinecarboxamide methanesulfonate salt) | TRPP3 channel inhibitor (IC50=0.14um). Also inhibits epithelial Na+ channels (Kd=0.4nm for a high affinity site on the epithelial Na+ channel). Derivative of amiloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 1161-94-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Phenamil methanesulfonate | Phenamil methanesulfonate, an analog of Amiloride (HY-B0285), is a more potent and less reversible epithelial sodium channel (ENaC) blocker with an IC 50 of 400 nM [2]. Phenamil methanesulfonate is also a competive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca 2+ transport with an IC 50 of 140 nM in a Ca 2+ uptake assay [1]. Phenamil methanesulfonate is an intriguing small molecule to promote bone repair by strongly activating BMP signaling pathway [4]. Phenamil methanesulfonate is used for the research of cystic fibrosis lung disease [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1161-94-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-108464A. |  |
| Phenamil methanesulfonate salt | solid. Group: Fluorescence/luminescence spectroscopy. |  |
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