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| Product | Description | |
|---|---|---|
| Phosphodiesterase 2A active from Rat, Recombinant | cGMP-dependent 3',5'-cyclic phosphodiesterase is an enzyme that in humans is encoded by the PDE2A gene. Rat pde2a (genbank accession no. nm_00143847) full length with n-terminal his-gst-tag, mw=133 kda, expressed in a baculovirus infected sf9 cell expression system. Group: Enzymes. Synonyms: PDE2A; phosphodiesterase 2A, cGMP-stimulated; CGS-PDE; PDE2A1; PED2A4; cGSPDE. Purity: > 56% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 133 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Rat. PDE2A; phosphodiesterase 2A, cGMP-stimulated; CGS-PDE; PDE2A1; PED2A4; cGSPDE. Cat No: NATE-0520. |  |
| Phosphodiesterase 2A FLAG tag active from Human, Recombinant | cGMP-dependent 3',5'-cyclic phosphodiesterase is an enzyme that in humans is encoded by the PDE2A gene. Human pde2a (genbank accession no. nm_002599) amino-acids 2-941 with n-terminal flag-tag, mw=106 kda, expressed in a baculovirus infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: PDE2A; phosphodiesterase 2A, cGMP-stimulated; CGS-PDE; PDE2A1; PED2A4; cGSPDE. Purity: > 88% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 106 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Human. PDE2A; phosphodiesterase 2A, cGMP-stimulated; CGS-PDE; PDE2A1; PED2A4; cGSPDE. Cat No: NATE-0519. | |
| Phosphodiesterase 3A from Human, Recombinant | PDE3 is a phosphodiesterase. The PDEs belong to at least eleven related gene families, which are different in their primary structure, substrate affinity, responses to effectors, and regulation mechanism. Most of the PDE families are composed of more than one gene. PDE3 is clinically significant because of its role in regulating heart muscle, vascular smooth muscle and platelet aggregation. PDE3 inhibitors have been developed as pharmaceuticals, but their use is limited by arrhythmic effects and they can increase mortality in some applications. N-terminal gst-tagged 193.3 kda protein containing amino acids 484-1141. Applications: Human phosphodiesterase 3a has been used...tidine 3':5'-monophosphate phosphodiesterase (cyclic CMP); cyclic 3',5-nucleotide monophosphate phosphodiesterase; nucleoside 3',5'-cyclic phosphate diesterase; nucleoside-3',5-monophosphate phosphodiesterase; EC 3.1.4.17; PDE3A. Enzyme Commission Number: EC 3.1.4.17. CAS No. 9040-59-9. PDE. Mole weight: 193.3 kDa. Storage: -70°C. Form: Supplied as a solution in 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% TWEEN-20, 50% glycerol, 20 mM glutathione, and 3 mM DTT. Source: Sf9 cells. Species: Human. cyclic 3',5'-mononucleotide phosphodiesterase; PDE; cyclic 3',5'-nucleotide phosphodiesterase; cyclic 3',5'-phosphodiesterase; 3',5'-nucleotide phosphodiesterase; 3':5'-cyclic nu | |
| Phosphodiesterase 3B | recombinant, expressed in Sf9 cells. Group: Fluorescence/luminescence spectroscopy. |  |
| Phosphodiesterase 3B, Recombinant | PDE3 is a phosphodiesterase. The PDEs belong to at least eleven related gene families, which are different in their primary structure, substrate affinity, responses to effectors, and regulation mechanism. Most of the PDE families are composed of more than one gene. PDE3 is clinically significant because of its role in regulating heart muscle, vascular smooth muscle and platelet aggregation. PDE3 inhibitors have been developed as pharmaceuticals, but their use is limited by arrhythmic effects and they can increase mortality in some applications. N-terminal gst-tagged 86 kda protein containing amino acids 592-end. Applications: Phosphodiesterase 3b has been used in a study to evaluate the evidence for biological effects of metformin in operable breast cancer. phosphodiesterase 3b has also been used in a study to investigate the role of intracellular and intercellular communication in perfusion distribution of erythr ocyte-derived atp. Group: Enzymes. Synony. Enzyme Commission Number: EC 3.1.4.17. CAS No. 9040-59-9. PDE. Mole weight: 86 kDa. Storage: -70°C. Form: Supplied as a solution in 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 50% glycerol, and 3 mM DTT. Source: Sf9 cells. cyclic 3',5'-mononucleotide phosphodiesterase; PDE; cyclic 3',5'-nucleotide phosphodiesterase; cyclic 3',5'-phosphodiesterase; 3',5'-nucleotide phosphodiesterase; 3 | |
| Phosphodiesterase 4 Inhibitor | An phosphodiesterase 4 (PDE4) inhibitor with IC50 values of 33 and 21 nm for PDE4B and PDE4D, respectively. Synonyms: PDE4 Inhibitor; 3,5-Dimethyl-1-(3-nitrophenyl)-1H-pyrazole-4-carboxylic acid ethyl ester; Ethyl 3,5-dimethyl-1-(3-nitrophenyl)pyrazole-4-carboxylate. Grades: ≥98%. CAS No. 346440-86-6. Molecular formula: C14H15N3O4. Mole weight: 289.3. |  |
| Phosphodiesterase 5A1 from Human, Recombinant | PDE5 regulates vascular smooth muscle contraction and is involved in NO-cGMP signaling in platelets to control aggregation. PDE5 may also be involved in the regulation of cGMP signaling in the brain and may modulate pressure-induced cardiac hypertrophy and fibrosis. N-terminal gst-tagged 126 kda full-length protein. Applications: Phosphodiesterase (pde) is an enzyme that is used to breaks phosphodiester bonds. pde5 is a molecular target for the treatment of erectile dysfunction and pulmonary hypertension. pde5 is used to find novel pde5 inhibitors. Group: Enzymes. Synonyms: CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A; 3',5'-cyclic-GMP phosphodiesterase, PDE 5A1. Phosphodiesterase. Mole weight: 126 kDa. Storage: -70°C. Form: Supplied as a solution in 20% glycerol containing 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% TWEEN 20 and 3 mM DTT. Source: Sf9 cells. Species: Human. CN5N; phosphodiesterase 5A, cGMP-specific; PDE5A1; PDE5A; 3',5'-cyclic-GMP phosphodiesterase, PDE 5A1. Cat No: NATE-0527. | |
| Phosphodiesterase 5A1 human | recombinant, expressed in Sf9 cells. Group: Fluorescence/luminescence spectroscopy. | |
| Phosphodiesterase 7A active from Mouse, Recombinant | Mouse PDE7A (GenBank Accession No. NM_001122759) amino acids 147-482 (end) with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system. Mouse pde7a (genbank accession no. nm_001122759) amino acids 147-482 (end) with n-terminal gst-tag, mw=65 kda, expressed in a baculovirus-infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: PDE7A; phosphodiesterase 7A; cAMP-specific 3,5-cyclic phosphodiesterase 7A. Purity: > 22% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 65 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Mouse. PDE7A; phosphodiesterase 7A; cAMP-specific 3,5-cyclic phosphodiesterase 7A. Cat No: NATE-0529. | |
| Phosphodiesterase 7A active from Rat, Recombinant | Rat PDE7A (GenBank Accession No. NM_031080) amino acids 147-482 (end) with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system. Rat pde7a (genbank accession no. nm_031080) amino acids 147-482 (end) with n-terminal gst-tag, mw=65 kda, expressed in a baculovirus-infected sf9 cell expression system. Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Group: Enzymes. Synonyms: PDE7A; phosphodiesterase 7A; cAMP-specific 3,5-cyclic phosphodiesterase 7A. Purity: > 30% (SDS-PAGE). Phosphodiesterase. Mole weight: mol wt 65 kDa. Storage: -70°C. Form: aqueous solution. Source: Baculovirus infected Sf9 cells. Species: Rat. PDE7A; phosphodiesterase 7A; cAMP-specific 3,5-cyclic phosphodiesterase 7A. Cat No: NATE-0530. | |
| phosphodiesterase I | Hydrolyses both ribonucleotides and deoxyribonucleotides. Has low activity towards polynucleotides. A 3'-phosphate terminus on the substrate inhibits hydrolysis. Group: Enzymes. Synonyms: 5'-exonuclease; 5'-phosphodiesterase; 5'-nucleotide phosphodiesterase; oligonucleate 5'-nucleotidohydrolase; 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I; 5'-NPDase; 5'-PDase; 5'-PDE; 5'NPDE; alkaline phosphodiesterase; nucleotide pyrophosphatase/phosphodiesterase I; orthophosphoric diester phosphohydrolase; PDE I; phosphodiesterase (ambiguous); exonuclease I. Enzyme Commission Number: EC 3.1.4.1. CAS No. 9025-82-5. PDE. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3710; phosphodiesterase I; EC 3.1.4.1; 9025-82-5; 5'-exonuclease; 5'-phosphodiesterase; 5'-nucleotide phosphodiesterase; oligonucleate 5'-nucleotidohydrolase; 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I; 5'-NPDase; 5'-PDase; 5'-PDE; 5'NPDE; alkaline phosphodiesterase; nucleotide pyrophosphatase/phosphodiesterase I; orthophosphoric diester phosphohydrolase; PDE I; phosphodiesterase (ambiguous); exonuclease I. Cat No: EXWM-3710. | |
| Phosphodiesterase I from Bothrops atrox | Type V, crude dried venom, ?0.01 unit/mg solid. Group: Fluorescence/luminescence spectroscopy. | |
| Phosphodiesterase I from Crotalus adamanteus venom | Type VI, crude dried venom, ?0.01 unit/mg solid. Group: Fluorescence/luminescence spectroscopy. | |
| Phosphodiesterase I from Crotalus atrox (Western Diamondback Rattlesnake) | Type IV, crude dried venom, ?0.01 unit/mg solid. Group: Fluorescence/luminescence spectroscopy. | |
| Phosphodiesterase II, Bovine Spleen | Phosphodiesterase II (EC 3.1.16.1), namely phosphodiesterase 2, is mainly involved in the hydrolysis of the important second messengers cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), and is often used in biochemical research. Phosphodiesterase II is expressed in a variety of tissues, such as the adrenal medulla, brain, heart, platelets, macrophages and endothelial cells, and is involved in the regulation of many different intracellular processes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3-Exonuclease. CAS No. 9068-54-6. Pack Sizes: 10 U. Product ID: HY-P2867. |  |
| 2',3'-cyclic-nucleotide 2'-phosphodiesterase | Also hydrolyses 3'-nucleoside monophosphates and bis-4-nitrophenyl phosphate, but not 3'-deoxynucleotides. Similar reactions are carried out by EC 3.1.27.3 (ribonuclease T1) and EC 3.1.27.5 (pancreatic ribonuclease). Group: Enzymes. Synonyms: ribonucleoside 2',3'-cyclic phosphate diesterase; 2',3 -cyclic AMP phosphodiesterase; 2',3'-cyclic nucleotidase; cyclic 2',3'-nucleotide 2'-phosphodiesterase; cyclic 2',3'-nucleotide phosphodiesterase; 2',3'-cyclic nucleoside monophosphate phosphodiesterase; 2',3'-cyclic AMP 2'-phosphohydrolase; cyclic phosphodiesterase:3'-nucleotidase; 2',3'-cyclic n. Enzyme Commission Number: EC 3.1.4.16. CAS No. 9037-18-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3715; 2',3'-cyclic-nucleotide 2'-phosphodiesterase; EC 3.1.4.16; 9037-18-7; ribonucleoside 2',3'-cyclic phosphate diesterase; 2',3 -cyclic AMP phosphodiesterase; 2',3'-cyclic nucleotidase; cyclic 2',3'-nucleotide 2'-phosphodiesterase; cyclic 2',3'-nucleotide phosphodiesterase; 2',3'-cyclic nucleoside monophosphate phosphodiesterase; 2',3'-cyclic AMP 2'-phosphohydrolase; cyclic phosphodiesterase:3'-nucleotidase; 2',3'-cyclic nucleotide phosphohydrolase; 2':3'-cyclic phosphodiesterase; 2':3'-cyclic nucleotide phosphodiesterase:3'-nucleotidase. Cat No: EXWM-3715. | |
| 2',3'-cyclic-nucleotide 3'-phosphodiesterase | The brain enzyme acts on 2',3'-cyclic AMP more rapidly than on the UMP or CMP derivatives. An enzyme from liver acts on 2',3'-cyclic CMP more rapidly than on the purine derivatives; it also hydrolyses the corresponding 3',5'-cyclic phosphates, but more slowly. This latter enzyme has been called cyclic-CMP phosphodiesterase. Group: Enzymes. Synonyms: cyclic-CMP phosphodiesterase; 2',3'-cyclic AMP phosphodiesterase; cyclic 2',3'-nucleotide 3'-phosphodiesterase; cyclic 2',3'-nucleotide phosphodiesterase; 2',3'-cyclic nucleoside monophosphate phosphodiesterase; 2',3'-cyclic nucleotide 3'-phosphohydrolase; CNPase; 2',3'-cyclic nucleotide phosphohydrolase; 2':3'-cyclic nucleotide 3'-phosphod. Enzyme Commission Number: EC 3.1.4.37. CAS No. 60098-35-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3720; 2',3'-cyclic-nucleotide 3'-phosphodiesterase; EC 3.1.4.37; 60098-35-3; cyclic-CMP phosphodiesterase; 2',3'-cyclic AMP phosphodiesterase; cyclic 2',3'-nucleotide 3'-phosphodiesterase; cyclic 2',3'-nucleotide phosphodiesterase; 2',3'-cyclic nucleoside monophosphate phosphodiesterase; 2',3'-cyclic nucleotide 3'-phosphohydrolase; CNPase; 2',3'-cyclic nucleotide phosphohydrolase; 2':3'-cyclic nucleotide 3'-phosphodiesterase; 2':3'-CNMP-3'-ase. Cat No: EXWM-3720. | |
| 3',5'-cyclic-AMP phosphodiesterase | Requires Mg2+ or Mn2+ for activity. This enzyme is specific for 3',5'-cAMP and does not hydrolyse other nucleoside 3',5'-cyclic phosphates such as cGMP (cf. EC 3.1.4.17, 3,5-cyclic-nucleotide phosphodiesterase and EC 3.1.4.35, 3,5-cyclic-GMP phosphodiesterase). It is involved in modulation of the levels of cAMP, which is a mediator in the processes of cell transformation and proliferation. Group: Enzymes. Synonyms: cAMP-specific phosphodiesterase; cAMP-specific PDE; PDE1; PDE2A; PDE2B; PDE4; PDE7; PDE8; PDEB1; PDEB2. Enzyme Commission Number: EC 3.1.4.53. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3736; 3',5'-cyclic-AMP phosphodiesterase; EC 3.1.4.53; cAMP-specific phosphodiesterase; cAMP-specific PDE; PDE1; PDE2A; PDE2B; PDE4; PDE7; PDE8; PDEB1; PDEB2. Cat No: EXWM-3736. | |
| 3',5'-cyclic-GMP phosphodiesterase | This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. Group: Enzymes. Synonyms: guanosine cyclic 3',5'-phosphate phosphodiesterase; cyclic GMP phosphodiesterase; cyclic 3',5'-GMP phosphodiesterase; cyclic guanosine 3',5'-monophosphate phosphodiesterase; cyclic guanosine 3',5'-phosphate phosphodiesterase; cGMP phosphodiesterase; cGMP-PDE. Enzyme Commission Number: EC 3.1.4.35. CAS No. 9068-52-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3719; 3',5'-cyclic-GMP phosphodiesterase; EC 3.1.4.35; 9068-52-4; guanosine cyclic 3',5'-phosphate phosphodiesterase; cyclic GMP phosphodiesterase; cyclic 3',5'-GMP phosphodiesterase; cyclic guanosine 3',5'-monophosphate phosphodiesterase; cyclic guanosine 3',5'-phosphate phosphodiesterase; cGMP phosphodiesterase; cGMP-PDE. Cat No: EXWM-3719. | |
| 3',5'-cyclic-nucleotide phosphodiesterase | Acts on 3',5'-cyclic AMP, 3',5'-cyclic dAMP, 3',5'-cyclic IMP, 3',5'-cyclic GMP and 3',5'-cyclic CMP. Group: Enzymes. Synonyms: cyclic 3',5'-mononucleotide phosphodiesterase; PDE; cyclic 3',5'-nucleotide phosphodiesterase; cyclic 3',5'-phosphodiesterase; 3',5'-nucleotide phosphodiesterase; 3':5'-cyclic nucleotide 5'-nucleotidohydrolase; 3',5'-cyclonucleotide phosphodiesterase; cyclic nucleotide phosphodiesterase; 3', 5'-cyclic nucleoside monophosphate p. Enzyme Commission Number: EC 3.1.4.17. CAS No. 9040-59-9. PDE. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3716; 3',5'-cyclic-nucleotide phosphodiesterase; EC 3.1.4.17; 9040-59-9; cyclic 3',5'-mononucleotide phosphodiesterase; PDE; cyclic 3',5'-nucleotide phosphodiesterase; cyclic 3',5'-phosphodiesterase; 3',5'-nucleotide phosphodiesterase; 3':5'-cyclic nucleotide 5'-nucleotidohydrolase; 3',5'-cyclonucleotide phosphodiesterase; cyclic nucleotide phosphodiesterase; 3', 5'-cyclic nucleoside monophosphate phosphodiesterase; 3': 5'-monophosphate phosphodiesterase (cyclic CMP); cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP); cyclic 3',5-nucleotide monophosphate phosphodiesterase; nucleoside 3',5'-cyclic phosphate diesterase; nucleoside-3',5-monophosphate phosphodiesterase. Cat No: EXWM-3716. | |
| 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase | Contains one zinc atom and one iron atom per subunit of the dodecameric enzyme. It hydrolyses 7,8-dihydroneopterin 2',3'-cyclic phosphate, a step in tetrahydromethanopterin biosynthesis. In vitro the enzyme forms 7,8-dihydroneopterin 2'-phosphate and 7,8-dihydroneopterin 3'-phosphate at a ratio of 4:1. Group: Enzymes. Synonyms: MptB. Enzyme Commission Number: EC 3.1.4.56. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3739; 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase; EC 3.1.4.56; MptB. Cat No: EXWM-3739. | |
| [acyl-carrier-protein] phosphodiesterase | The enzyme cleaves acyl-[acyl-carrier-protein] species with acyl chains of 6-16 carbon atoms although it appears to demonstrate a preference for the unacylated acyl-carrier protein (ACP) and short-chain ACPs over the medium- and long-chain species. Deletion of the gene encoding this enzyme abolishes ACP prosthetic-group turnover in vivo. Activation of apo-ACP to form the holoenzyme is carried out byEC 2.7.8.7, holo-[acyl-carrier-protein] synthase. Group: Enzymes. Synonyms: ACP hydrolyase; ACP phosphodiesterase; AcpH; [acyl-carrier-protein] 4'-pantetheine-phosphohydrolase; holo-[acyl-carrier-protein] 4'-pantetheine-phosphohydrolase. Enzyme Commission Number: EC 3.1.4.14. CAS No. 37288-21-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3714; [acyl-carrier-protein] phosphodiesterase; EC 3.1.4.14; 37288-21-4; ACP hydrolyase; ACP phosphodiesterase; AcpH; [acyl-carrier-protein] 4'-pantetheine-phosphohydrolase; holo-[acyl-carrier-protein] 4'-pantetheine-phosphohydrolase. Cat No: EXWM-3714. | |
| alkylglycerophosphoethanolamine phosphodiesterase | Also acts on acyl and choline analogues. Group: Enzymes. Synonyms: lysophospholipase D. Enzyme Commission Number: EC 3.1.4.39. CAS No. 62213-15-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3722; alkylglycerophosphoethanolamine phosphodiesterase; EC 3.1.4.39; 62213-15-4; lysophospholipase D. Cat No: EXWM-3722. | |
| Anti-Phosphodiesterase 6? antibody produced in rabbit | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Phosphodiesterase 6?? antibody produced in rabbit | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| CMP-N-acylneuraminate phosphodiesterase | This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. Group: Enzymes. Synonyms: CMP-sialate hydrolase; CMP-sialic acid hydrolase; CMP-N-acylneuraminic acid hydrolase; cytidine monophosphosialic hydrolase; cytidine monophosphosialate hydrolase; cytidine monophosphate-N-acetylneuraminic acid hydrolase; CMP-N-acetylneuraminate hydrolase. Enzyme Commission Number: EC 3.1.4.40. CAS No. 55326-41-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3724; CMP-N-acylneuraminate phosphodiesterase; EC 3.1.4.40; 55326-41-5; CMP-sialate hydrolase; CMP-sialic acid hydrolase; CMP-N-acylneuraminic acid hydrolase; cytidine monophosphosialic hydrolase; cytidine monophosphosialate hydrolase; cytidine monophosphate-N-acetylneuraminic acid hydrolase; CMP-N-acetylneuraminate hydrolase. Cat No: EXWM-3724. | |
| cyclic-guanylate-specific phosphodiesterase | Requires Mg2+ or Mn2+ for activity and is inhibited by Ca2+ and Zn2+. Contains a heme unit. This enzyme linearizes cyclic di-3,5-guanylate, the product of EC 2.7.7.65, diguanylate cyclase and an allosteric activator of EC 2.4.1.12, cellulose synthase (UDP-forming), rendering it inactive. It is the balance between these two enzymes that determines the cellular level of c-di-GMP. Group: Enzymes. Synonyms: cyclic bis(3?5')diguanylate phosphodiesterase; c-di-GMP-specific phosphodiesterase; c-di-GMP phosphodiesterase; phosphodiesterase (misleading); phosphodiesterase A1; PDEA1; VieA. Enzyme Commission Number: EC 3.1.4.52. CAS No. 338732-46-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3735; cyclic-guanylate-specific phosphodiesterase; EC 3.1.4.52; 338732-46-0; cyclic bis(3?5')diguanylate phosphodiesterase; c-di-GMP-specific phosphodiesterase; c-di-GMP phosphodiesterase; phosphodiesterase (misleading); phosphodiesterase A1; PDEA1; VieA. Cat No: EXWM-3735. | |
| dolichylphosphate-glucose phosphodiesterase | This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. This enzyme participates in n-glycan biosynthesis. Group: Enzymes. Synonyms: dolichol phosphoglucose phosphodiesterase; Dol-P-Glc phosphodiesterase. Enzyme Commission Number: EC 3.1.4.48. CAS No. 89287-42-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3731; dolichylphosphate-glucose phosphodiesterase; EC 3.1.4.48; 89287-42-3; dolichol phosphoglucose phosphodiesterase; Dol-P-Glc phosphodiesterase. Cat No: EXWM-3731. | |
| dolichylphosphate-mannose phosphodiesterase | This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. Group: Enzymes. Synonyms: mannosylphosphodolichol phosphodiesterase. Enzyme Commission Number: EC 3.1.4.49. CAS No. 111839-07-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3732; dolichylphosphate-mannose phosphodiesterase; EC 3.1.4.49; 111839-07-7; mannosylphosphodolichol phosphodiesterase. Cat No: EXWM-3732. | |
| glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase | The enzyme is specific for the product of EC 2.7.8.19 UDP-glucose-glycoprotein glucose phosphotransferase. Group: Enzymes. Synonyms: α-glucose-1-phosphate phosphodiesterase. Enzyme Commission Number: EC 3.1.4.51. CAS No. 123940-44-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3734; glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase; EC 3.1.4.51; 123940-44-3; α-glucose-1-phosphate phosphodiesterase. Cat No: EXWM-3734. | |
| glycerol-1,2-cyclic-phosphate 2-phosphodiesterase | Acts on both stereoisomers of the substrate and also, more slowly, on 3',5'-cyclic AMP and on 2',3'-cyclic AMP. Group: Enzymes. Synonyms: rac-glycerol 1:2-cyclic phosphate 2-phosphodiesterase. Enzyme Commission Number: EC 3.1.4.42. CAS No. 69458-89-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3726; glycerol-1,2-cyclic-phosphate 2-phosphodiesterase; EC 3.1.4.42; 69458-89-5; rac-glycerol 1:2-cyclic phosphate 2-phosphodiesterase. Cat No: EXWM-3726. | |
| glycerophosphocholine phosphodiesterase | Also acts on sn-glycero-3-phosphoethanolamine. Group: Enzymes. Synonyms: glycerophosphinicocholine diesterase; glycerylphosphorylcholinediesterase; sn-glycero-3-phosphorylcholine diesterase; glycerolphosphorylcholine phosphodiesterase; glycerophosphohydrolase. Enzyme Commission Number: EC 3.1.4.2. CAS No. 9025-85-8. Glycerophosphocholine phosphodiesterase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3717; glycerophosphocholine phosphodiesterase; EC 3.1.4.2; 9025-85-8; glycerophosphinicocholine diesterase; glycerylphosphorylcholinediesterase; sn-glycero-3-phosphorylcholine diesterase; glycerolphosphorylcholine phosphodiesterase; glycerophosphohydrolase. Cat No: EXWM-3717. | |
| glycerophosphodiester phosphodiesterase | Broad specificity for glycerophosphodiesters; glycerophosphocholine, glycerophosphoethanolamine, glycerophosphoglycerol and bis(glycerophospho)-glycerol are hydrolysed. Group: Enzymes. Synonyms: gene hpd protein; glycerophosphoryl diester phosphodiesterase; IgD-binding protein D. Enzyme Commission Number: EC 3.1.4.46. CAS No. 86280-59-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3730; glycerophosphodiester phosphodiesterase; EC 3.1.4.46; 86280-59-3; gene hpd protein; glycerophosphoryl diester phosphodiesterase; IgD-binding protein D. Cat No: EXWM-3730. | |
| glycerophosphoinositol inositolphosphodiesterase | This enzyme also hydrolyses Ins(cyclic1,2)P to Ins-1-P. Group: Enzymes. Synonyms: 1,2-cyclic-inositol-phosphate phosphodiesterase; D-myo-inositol 1:2-cyclic phosphate 2-phosphohydrolase; D-inositol 1,2-cyclic phosphate 2-phosphohydrolase; D-myo-inositol 1,2-cyclic phosphate 2-phosphohydrolase; 1-D-myo-inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase; inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase. Enzyme Commission Number: EC 3.1.4.43. CAS No. 9076-91-9 (from EC 3.1.4.36), 72414-13-2 (not distinguished from EC 3.1.4.44). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3727; glycerophosphoinositol inositolphosphodiesterase; EC 3.1.4.43; 9076-91-9 (from EC 3.1.4.36), 72414-13-2 (not distinguished from EC 3.1.4.44); 1,2-cyclic-inositol-phosphate phosphodiesterase; D-myo-inositol 1:2-cyclic phosphate 2-phosphohydrolase; D-inositol 1,2-cyclic phosphate 2-phosphohydrolase; D-myo-inositol 1,2-cyclic phosphate 2-phosphohydrolase; 1-D-myo-inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase; inositol-1,2-cyclic-phosphate 2-inositolphosphohydrolase. Cat No: EXWM-3727. | |
| Native Bothrops atrox Phosphodiesterase I | Phosphodiesterase I breaks phosphodiester bonds and catalyzes the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is released from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C. Group: Enzymes. Synonyms: Phosphodiesterase I; EC 3.1.4.1; 5'-exonuclease; 5'-phosphodiesterase; 5'-nucleotide phosphodiesterase; oligonucleate 5'-nucleotidohydrolase; 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I; 5'-NPDase; 5'-PDase; 5'-PDE; 5'NPDE; alkaline phosphodiesterase; nucleotide pyrophosphatase/phosphodiesterase I; orthophosphoric diester phosphohydrolase; PDE I; phosphodiesterase; exonuclease I. Enzyme Commission Number: EC 3.1.4.1. CAS No. 9025-82-5. PDE. Activity: > 0.01 unit/mg solid. Storage: -20°C. Form: crude dried venom. Source: Bothrops atrox. Phosphodiesterase I; EC 3.1.4.1; 5'-exonuclease; 5'-phosphodiesterase; 5'-nucleotide phosphodiesterase; oligonucleate 5'-nucleotidohydrolase; 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I; 5'-NPDase; 5'-PDase; 5'-PDE; 5'NPDE; alkaline phosphodiesterase; nucleotide pyrophosphatase/phosphodiesterase I; orthophosphoric diester phosphohydrolase; PDE I; phosphodiesterase; exonuclease I. Cat No: NATE-0511. | |
| Native Bovine Phosphodiesterase 3',5'-Cyclic Nucleotide Activator-deficient | Hydrolyzes the 3',5'-phosphodiester bond in cyclic nucleotide monophosphates, such as cAMP and cGMP, to the corresponding nucleotide 5'-monophosphate. Applications: Cyclic nucleotide phosphodiesterase has been investigated for its mechanism of activation as a function of calmodulin and ca2+. it has also been used in a study to show that the binding of trifluoperazine to the activator of cyclic nucleotide phosphodiesterase increases the activity by over 10-fold. for use in calmodulin (p 0270) assay. activity is reduced to <50% without calmodulin present. Group: Enzymes. Synonyms: cyclic 3',5'-mononucleotide phosphodiesterase; PDE; cyclic 3',5'-nucleotide ...th added activator). Storage: -20°C. Form: lyophilized powder (contains imidazole buffer salts and magnesium sulfate). Source: Bovine heart. Species: Bovine. cyclic 3',5'-mononucleotide phosphodiesterase; PDE; cyclic 3',5'-nucleotide phosphodiesterase; cyclic 3',5'-phosphodiesterase; 3',5'-nucleotide phosphodiesterase; 3':5'-cyclic nucleotide 5'-nucleotidohydrolase; 3',5'-cyclonucleotide phosphodiesterase; cyclic nucleotide phosphodiesterase; 3', 5'-cyclic nucleoside monophosphate phosphodiesterase; 3':5'-monophosphate phosphodiesterase (cyclic CMP); cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP); cyclic 3',5-nucleotide monophosphate phosphod | |
| Native Bovine Phosphodiesterase, 3',5'-cyclic-nucleotide-specific | Hydrolyzes the 3',5'-phosphodiester bond in cyclic nucleotide monophosphates, such as cAMP and cGMP, to the corresponding nucleotide 5'-monophosphate. Applications: May be used to assay the protein activator, calmodulin. Group: Enzymes. Synonyms: cyclic 3',5'-mononucleotide phosphodiesterase; PDE. Enzyme Commission Number: EC 3.1.4.17. CAS No. 9040-59-9. PDE. Mole weight: mol wt ~60 kDa. Activity: 15-30 units/mg protein (in the presence of 0.03 mM Ca2+ and a saturating level (10 units per ml) of calmodulin (P2277)). Storage: -20°C. Form: Lyophilized powder containing Tris-HCl buffer salts and lactose. Source: Bovine brain. Species: Bovine. cyclic 3',5'-mononucleotide phosphodiesterase; PDE; cyclic 3',5'-nucleotide phosphodiesterase; cyclic 3',5'-phosphodiesterase; 3',5'-nucleotide phosphodiesterase; 3':5'-cyclic nucleotide 5'-nucleotidohydrolase; 3',5'-cyclonucleotide phosphodiesterase; cyclic nucleotide phosphodiesterase; 3', 5'-cyclic nucleoside monophosphate phosphodiesterase; 3':5'-monophosphate phosphodiesterase (cyclic CMP); cytidine 3':5'-monophosphate phosphodiesterase (cyclic CMP); cyclic 3',5-nucleotide monophosphate phosphodiesterase; nucleoside 3',5'-cyclic phosphate diesterase; nucleoside-3',5-monophosphate phosphodiesterase; EC 3.1.4.17. Pack: Package size based on activated units. Cat No: NATE-0515. | |
| Native Bovine Phosphodiesterase II | Phosphodiesterase (PDE) is any enzyme that is used to breaks phosphodiester bonds. The enzyme acts on poly (A), poly (U), and poly (I). Native DNA and poly (C) are quite resistant to the action of this enzyme. Hydrolyzes RNA, RNA-Core, 3'-alkyl-and 3'-aryl-nucleoside phosphates, and polydeoxyribonucleotides with 3'-phosphate end groups to 3'-mononucleotides. Polynucleotides having 5'-phosphomonoester end groups are not attacked. Applications: Phosphodiesterase (pde) is any enzyme that is used to breaks phosphodiester bonds. it is a membrane-bound glycoprotein that is used to catalyze the hydrolysis of various nucleotide polyphosphates. phosphodiesterase ii has been used in t...yloxobutyl (pob) base adducts from dna. furthermore, it has been used along with micr oc occal endonuclease to hydrolyze purified dna to 3-nucleoside monophosphates. Group: Enzymes. Synonyms: 3'-exonuclease; spleen phosphodiesterase; 3'-nucleotide phosphodiesterase; phosphodiesterase II; spleen exonuclease; EC 3.1.16.1; 9068-54-6; PDE2. Enzyme Commission Number: EC 3.1.16.1. CAS No. 9068-54-6. PDE. Activity: > 5.0 units/mg protein. Storage: -20°C. Form: lyophilized powder. Source: Bovine spleen. Species: Bovine. 3'-exonuclease; spleen phosphodiesterase; 3'-nucleotide phosphodiesterase; phosphodiesterase II; spleen exonuclease; EC 3.1.16.1; 9068-54-6; PDE2. Cat No: NATE-0518. | |
| Native Crotalus adamanteus venom Phosphodiesterase I | Venom exonuclease (Phosphodiesterase I) successively hydrolyzes 5'-mononucleotides from 3'-OH-terminated ribo- and deoxyribo-oligonucleotides. The enzyme has an optimal pH range of 9.8-10.4 and a molecular weight of 115 kDa. Phosphodiesterase is inhibited by reducing agents such as glutathione, cysteine and ascorbic acids. It is completely inhibited by 5mM EDTA while ATP, ADP and AMP are partial inhibitors. The enzyme has an absolute requirement for Mg2+. Group: Enzymes. Synonyms: Phosphodiesterase I; EC 3.1.4.1; 5'-exonuclease; 5'-phosphodiesterase; 5'-nucleotide phosphodiesterase; oligonucleate 5'-nucleotidohydrolase; 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I; 5'-NPDase; 5'-PDase; 5'-PDE; 5'NPDE; alkaline phosphodies. Enzyme Commission Number: EC 3.1.4.1. CAS No. 9025-82-5. PDE. Activity: > 20 units per mg dry weight. Storage: -20°C. Form: Lyophilized in vials. Source: Crotalus adamanteus venom. Phosphodiesterase I; EC 3.1.4.1; 5'-exonuclease; 5'-phosphodiesterase; 5'-nucleotide phosphodiesterase; oligonucleate 5'-nucleotidohydrolase; 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I; 5'-NPDase; 5'-PDase; 5'-PDE; 5'NPDE; alkaline phosphodiesterase; nucleotide pyrophosphatase/phosphodiesterase I; orthophosphoric diester phosphohydrolase; PDE I; phosphodiesterase; exonuclease I. Cat No: NATE-0512. | |
| Native Crotalus atrox (Western Diamondback Rattlesnake) Phosphodiesterase I | Phosphodiesterase I breaks phosphodiester bonds and catalyzes the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is released from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C. Applications: Phosphodiesterase (pde) is any enzyme that is used to breaks phosphodiester bonds. phosphodiesterase i from western diamondback rattlesnake, is used in phosphodiesterase activation assays for calmodulin. it is added to hydrolyze amp. it is a membrane-bound glycoprotein that is used to catalyze the hydrolysis of various nucleotide polyphosphates. Group: Enzymes. Synonyms: Phosphodiesterase I; EC 3.1.4.1; 5'-exonuclease; 5'-phosphodiesterase; 5'-nucleotide phosphodi. Enzyme Commission Number: EC 3.1.4.1. CAS No. 9025-82-5. PDE. Activity: > 0.01 unit/mg solid. Storage: -20°C. Form: crude dried venom. Source: Crotalus atrox (Western Diamondback Rattlesnake). Phosphodiesterase I; EC 3.1.4.1; 5'-exonuclease; 5'-phosphodiesterase; 5'-nucleotide phosphodiesterase; oligonucleate 5'-nucleotidohydrolase; 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I; 5'-NPDase; 5'-PDase; 5'-PDE; 5'NPDE; alkaline phosphodiesterase; nucleotide pyrophosphatase/phosphodiesterase I; orthophosphoric diester phosphohydrolase; PDE I; phosphodiesterase; exonuclease I. Cat No: NATE-0513. | |
| Native Gliocladium roseum Glycerophosphocholine phosphodiesterase | In enzymology, a glycerophosphocholine phosphodiesterase (EC 3.1.4.2) is an enzyme that catalyzes the chemical reaction: sn-glycero-3-phosphocholine + H2O<-> choline + sn-glycerol 3-phosphate. Thus, the two substrates of this enzyme are sn-glycero-3-phosphocholine and H2O, whereas its two products are choline and sn-glycerol 3-phosphate. Native glycerophosphocholine phosphodiesterase (ec 3.1.4.2) was purified from gliocladium roseum. Group: Enzymes. Synonyms: glycerophosphocholine phosphodiesterase; EC 3.1.4.2; sn-glycero-3-phosphocholine glycerophosphohydrolase; glycerophosphinicocholine diesterase; glycerylphosphorylcholinediesterase; sn-glycero-3-phosphorylcholine diesterase; glycerolphosphorylcholine phospho. Enzyme Commission Number: EC 3.1.4.2. CAS No. 9025-85-8. Glycerophosphocholine phosphodiesterase. Activity: > 10.0 U/mg. Appearance: White to brownish powder. Storage: Store in tightly closed containers, desiccated, protected from light, at-20°C. Form: Freeze dried powder. Source: Gliocladium roseum. glycerophosphocholine phosphodiesterase; EC 3.1.4.2; sn-glycero-3-phosphocholine glycerophosphohydrolase; glycerophosphinicocholine diesterase; glycerylphosphorylcholinediesterase; sn-glycero-3-phosphorylcholine diesterase; glycerolphosphorylcholine phosphodiesterase; glycerophosphohydrolase. Cat No: DIA-153. | |
| Native Mold sn-Glycerol-3-phosphocholine Phosphodiesterase | In enzymology, a glycerophosphocholine phosphodiesterase (EC 3.1.4.2) is an enzyme that catalyzes the chemical reaction:sn-glycero-3-phosphocholine + H2O<-> choline + sn-glycerol 3-phosphate. Thus, the two substrates of this enzyme are sn-glycero-3-phosphocholine and H2O, whereas its two products are choline and sn-glycerol 3-phosphate. This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. Group: Enzymes. Synonyms: glycerophosphinicocholine diesterase; glycerylphosphorylcholinediesterase; sn-glycero-3-phosphorylcholine diesterase; glycerolphosphorylcholine phosphodiesterase; glycerophosphohydrolase; EC 3.1.4.2; 9025-85-8. Enzyme Commission Number: EC 3.1.4.2. CAS No. 9025-85-8. Glycerophosphocholine phosphodiesterase. Activity: > 5 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing Tris buffer salt. Source: Mold. glycerophosphinicocholine diesterase; glycerylphosphorylcholinediesterase; sn-glycero-3-phosphorylcholine diesterase; glycerolphosphorylcholine phosphodiesterase; glycerophosphohydrolase; EC 3.1.4.2; 9025-85-8. Cat No: NATE-0674. | |
| Native Porcine Phosphodiesterase, 3',5'-Cyclic Nucleotide, Activator-deficient | PDE3 is a phosphodiesterase. The PDEs belong to at least eleven related gene families, which are different in their primary structure, substrate affinity, responses to effectors, and regulation mechanism. Most of the PDE families are composed of more than one gene. PDE3 is clinically significant because of its role in regulating heart muscle, vascular smooth muscle and platelet aggregation. PDE3 inhibitors have been developed as pharmaceuticals, but their use is limited by arrhythmic effects and they can increase mortality in some applications. Applications: May be used to assay the protein activator, calmodulin. Group: Enzymes. Synonyms: cyclic 3',5'-m...finity chromatography. PDE. Mole weight: mol wt ~60 kDa. Storage: -20°C. Form: Lyophilized preparation which has been depleted of calmodulin and containing buffer salts as Tris-HCl. Source: Porcine brain. Species: Porcine. cyclic 3',5'-mononucleotide phosphodiesterase; PDE; cyclic 3',5'-nucleotide phosphodiesterase; cyclic 3',5'-phosphodiesterase; 3',5'-nucleotide phosphodiesterase; 3':5'-cyclic nucleotide 5'-nucleotidohydrolase; 3',5'-cyclonucleotide phosphodiesterase; cyclic nucleotide phosphodiesterase; 3', 5'-cyclic nucleoside monophosphate phosphodiesterase; 3':5'-monophosphate phosphodiesterase (cyclic CMP); cytidine 3':5'-monophosphate phosphodie | |
| PDE10A Inhibitor, Cpd15 (Phosphodiesterase 10A Inhibitor, (6-chloro-3,8-dimethyl-1H-pyrazolo[3,4-b]quinolin-4-yl)(2-methylpyrimidin-5-yl)methanol) | A cell-permeable pyrazoloquinoline compound that acts as a potent phosphodiesterase 10A inhibitor (Ki≤5nM against human PDE10A), while exhibiting >500-fold selectivity over other human PDEs 1-11 and little activity against CYP3A4 (IC50 >20uM) or a panel of 23 kinases (IC50 >30uM). Reported to be orally available in monkey and rat species and be efficacious in reversing nMDAR antagonist (+)-MK-801-induced hyperactivity in a ratsl (MED = 10mg/kg p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??ClN?O. US Biological Life Sciences. |  Worldwide |
| phosphoribosyl 1,2-cyclic phosphate phosphodiesterase | Binds Mn2+ and Zn2+. Isolated from the bacterium Escherichia coli, where it participates in the degradation of methylphosphonate. Group: Enzymes. Synonyms: phnP (gene name). Enzyme Commission Number: EC 3.1.4.55. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3738; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase; EC 3.1.4.55; phnP (gene name). Cat No: EXWM-3738. | |
| RO 20-1724, cAMP-specific Phosphodiesterase Inhibitor (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) | Cell-permeable. A potent,selective, cAMP-specific phosphodiesterase inhibitor (PDE IV, IC50 = 2 µM). Inhibits superoxide generation and platelet aggregation stimulated by arachidonic acid. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 29925-17-5. Pack Sizes: 50mg, 250mg. US Biological Life Sciences. | Worldwide |
| serine-ethanolaminephosphate phosphodiesterase | Acts only on those phosphodiesters that have ethanolamine as a component part of the molecule. Group: Enzymes. Synonyms: serine ethanolamine phosphodiester phosphodiesterase; SEP diesterase. Enzyme Commission Number: EC 3.1.4.13. CAS No. 37288-20-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3713; serine-ethanolaminephosphate phosphodiesterase; EC 3.1.4.13; 37288-20-3; serine ethanolamine phosphodiester phosphodiesterase; SEP diesterase. Cat No: EXWM-3713. | |
| sphingomyelin phosphodiesterase | Has very little activity on phosphatidylcholine. Group: Enzymes. Synonyms: neutral sphingomyelinase. Enzyme Commission Number: EC 3.1.4.12. CAS No. 9031-54-3. SMase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3712; sphingomyelin phosphodiesterase; EC 3.1.4.12; 9031-54-3; neutral sphingomyelinase. Cat No: EXWM-3712. | |
| sphingomyelin phosphodiesterase D | Does not act on phosphatidylcholine, but hydrolyses 2-lysophosphatidylcholine to choline and 2-lysophosphatidate. Group: Enzymes. Synonyms: sphingomyelinase D. Enzyme Commission Number: EC 3.1.4.41. CAS No. 54992-31-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3725; sphingomyelin phosphodiesterase D; EC 3.1.4.41; 54992-31-3; sphingomyelinase D. Cat No: EXWM-3725. | |
| 1,3-Dipropyl-7-methylxanthine | A phosphodiesterase inhibitor and caffeine analog with some selectivity for A2 adenosine receptors. UV lmax = 273 nm, log e=3.98. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 1,3-Dipropylxanthine | A phosphodiesterase inhibitor and caffeine analog with some selectivity for A2 adenosine receptors. UV lmax = 273 nm, log e=3.98. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 1-(4-Chloro-6,7-dimethoxyphthalazin-1-yl)piperidin-4-yl Ethylcarbamate | 1-(4-Chloro-6,7-dimethoxyphthalazin-1-yl)piperidin-4-yl Ethylcarbamate is a metabolite of Carbazeran (C175790), a phosphodiesterase inhibitor drug that exhibits chronictropic and inotropic effects. Group: Biochemicals. Grades: Highly Purified. CAS No. 1586753-74-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C18H23ClN4O4. US Biological Life Sciences. | Worldwide |
| 1-Acetyl-3-Piperidinone | 1-Acetyl-3-Piperidinone is used in the preparation of pyrazines as phosphodiesterase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 34456-78-5. Pack Sizes: 500mg, 5g. Molecular Formula: C7H11NO2, Molecular Weight: 141.169999999999. US Biological Life Sciences. | Worldwide |
| 1-Amino-3-cyclopentene-1-methanol | 1-Amino-3-cyclopentene-1-methanol is a reactant used in the synthesis of polycyclic guanines for therapeutic use as phosphodiesterase V inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 76910-11-7. Pack Sizes: 25mg, 250mg. Molecular Formula: C6H11NO, Molecular Weight: 113.16. US Biological Life Sciences. | Worldwide |
| 1-Chloro-6,7-dimethoxyphthalazine | A useful intermediate in the preparation of Carbazeran (C175790), a phosphodiesterase inhibitor drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 70724-23-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| 1-Cyclohexyl-5-(1,4-dibromobutyl)-1H-tetrazole | 1-Cyclohexyl-5-(1,4-dibromobutyl)-1H-tetrazole is an intermediate in the synthesis of Cilostazol (C441500), a potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C11H18Br2N4. US Biological Life Sciences. | Worldwide |
| 1-Cyclohexyl-5-(3-butenyl)tetrazole | 1-Cyclohexyl-5-(3-butenyl)tetrazole is a synthetic imppurity of Cilostazol (C441500), A potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 500mg. Molecular Formula: C11H18N4. US Biological Life Sciences. | Worldwide |
| 1-Cyclohexyl-5-(4-chlorobutyl)amino-1H-tetrazole | 1-Cyclohexyl-5-(4-chlorobutyl)amino-1H-tetrazole is an impurity of Cilostazol (C441500), a potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and an inhibitor of adenosine uptake and has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C11H20ClN5, Molecular Weight: 257.76. US Biological Life Sciences. | Worldwide |
| 1-Cyclohexyl-5-(tetrahydrofuran-2-yl)-1H-tetrazole | 1-Cyclohexyl-5-(tetrahydrofuran-2-yl)-1H-tetrazole is an intermediate in the synthesis of Cilostazol (C441500), a potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 250mg. Molecular Formula: C11H18N4O. US Biological Life Sciences. | Worldwide |
| 1-Decarboxyl-1-(bromoacetyl) Norneovardenafil | 1-Decarboxy-1-(bromoacetyl) Norneovardenafil is an intermediate in the preparation of the phosphodiesterase inhibitor Norneovardenafil (N824500). Group: Biochemicals. Alternative Names: 2-[5-(Bromoacetyl)-2-ethoxyphenyl]-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one. Grades: Highly Purified. CAS No. 358388-58-6. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| 1-Methyl-4-[[5-[[[2- (1-methyl-2-pyrrolidinyl) ethyl]amino]sulfonyl]-2-propoxybenzoyl]amino]-3-propyl-1H-pyrazole-5-carboxamide | Intermediate in the preparation of Udenafil , a phosphodiesterase 5 inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 382592-28-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 1-(Methyl)-4-nitro-3-(2,2,3,3,3-D5-propyl)-1H-pyrazole-5-carboxylic Acid | 1-(Methyl)-4-nitro-3-(2,2,3,3,3-D5-propyl)-1H-pyrazole-5-carboxylic Acid is a labelled intermediate of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1175992-94-5. Pack Sizes: 1mg, 10mg. Molecular Formula: C8H6D5N3O4, Molecular Weight: 218.22. US Biological Life Sciences. | Worldwide |
| 1-(Methyl-d3)-4-nitro-3-(2,2,3,3,3-D5-propyl)-1H-pyrazole-5-carboxylic Acid | 1-(Methyl-d3)-4-nitro-3-(2,2,3,3,3-D5-propyl)-1H-pyrazole-5-carboxylic Acid is a labelled intermediate of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1175993-00-6. Pack Sizes: 1mg, 10mg. Molecular Formula: C8H3D8N3O4, Molecular Weight: 221.24. US Biological Life Sciences. | Worldwide |
| 1-(Methyl-D3)-4-nitro-3-propyl-1H-pyrazole-5-carboxylic Acid | 1-(Methyl-D3)-4-nitro-3-propyl-1H-pyrazole-5-carboxylic Acid is a laballed Intermediate in the production of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 526203-29-2. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C8H8D3N3O4. US Biological Life Sciences. | Worldwide |
| 1-Phenyl-1H-pyrazole | 1-Phenyl-1H-pyrazole is an intermediate used to prepare heterocyclic sulfonamide γ-secretase inhibitors. It is also used in the synthesis of a 2-oxindole scaffold as a highly potent and brain-penetrant phosphodiesterase 10A inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1126-00-7. Pack Sizes: 1g, 5g. Molecular Formula: C9H8N2, Molecular Weight: 144.169999999999. US Biological Life Sciences. | Worldwide |
| (1R,3R)-Methyl-1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate | An intermediate in the synthesis of Tadafil, which is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| (1R,3R)-Methyl-1,2,3,4-tetrahydro-2-chloroacetyl-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate | An intermediate in the synthesis of Tadafil, which is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| (1S)-1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine | (1S)-1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine is an Apremilast (A729700) intermediate. Apremilast, an oral phosphodiesterase 4 inhibitor is used in the treatment of psoriatic arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 608141-42-0. Pack Sizes: 1mg, 5mg. Molecular Formula: C12H19NO4S. US Biological Life Sciences. | Worldwide |
| (1S,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-N-methyl-1H-pyrido[3,4-b]indole-3-carboxamide | (1S,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-N-methyl-1H-pyrido[3,4-b]indole-3-carboxamide is a byproduct formed in the preparation of Tadalafil (T004500); a phosphodiesterase 5 inhibitor used for the treatment of erectile dysfunction. Group: Biochemicals. Grades: Highly Purified. CAS No. 951661-85-1. Pack Sizes: 250mg, 2.5g. Molecular Formula: C20H19N3O3, Molecular Weight: 349.38. US Biological Life Sciences. | Worldwide |
| (1S,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-N-methyl-1H-pyrido[3,4-b]indole-3-carboxamide-d3 | (1S,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-N-methyl-1H-pyrido[3,4-b]indole-3-carboxamide-d3 is the isotope labelled analog of (1S,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-N-methyl-1H-pyrido[3,4-b]indole-3-carboxamide (B203535); a byproduct formed in the preparation of Tadalafil (T004500) which is a phosphodiesterase 5 inhibitor used for the treatment of erectile dysfunction. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C20H16D3N3O3, Molecular Weight: 352.4. US Biological Life Sciences. | Worldwide |
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