Phosphorylase Suppliers USA
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Product | Description | |
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Phosphorylase a from rabbit muscle Quick inquiry Where to buy Suppliers range | Phosphorylase a from rabbit muscle. Group: Heterocyclic Organic Compound. CAS No. 9032-10-4. | |
Phosphorylase b from rabbit muscle Quick inquiry Where to buy Suppliers range | Powder. Alternative Names: α-Glucan Phosphorylase. CAS No. 9012-69-5. | |
Phosphorylase Kinase β-Subunit Fragment 420-436 Quick inquiry Where to buy Suppliers range | Phosphorylase Kinase β-Subunit Fragment (420-436) is the β-Subunit fragment (peptide 430-436) of phosphorylase kinase. Phosphorylase kinase is a serine/threonine-specific protein kinase which activates glycogen phosphorylase to release glucose-1-phosphate from glycogen. Uses: Peptide Inhibitors. CAS No. 150829-21-3. Product ID: R1619. | |
Phosphorylase Kinase β-Subunit Fragment 420-436 Quick inquiry Where to buy Suppliers range | It is the β-subunit fragment (peptide 430-436) of phosphorylase kinase. Phosphokinase is a serine/threonine specific protein kinase that activates glycogen phosphorylase to release glucose-1-phosphate from glycogen. Synonyms: Lys-Arg-Asn-Pro-Gly-Ser-Gln-Lys-Arg-Phe-Pro-Ser-Asn-Cys-Gly-Arg-Asp; L-lysyl-L-arginyl-L-asparagyl-L-prolyl-glycyl-L-seryl-L-glutaminyl-L-lysyl-L-arginyl-L-phenylalanyl-L-prolyl-L-seryl-L-asparagyl-L-cysteinyl-glycyl-L-arginyl-L-aspartic acid; Phosphorylase Kinase b-Subunit Fragment (420-436). Grades: ≥95%. CAS No. 150829-21-3. Molecular formula: C79H131N31O25S. Mole weight: 1947.14. | |
Glycogen Phosphorylase Inhibitor Quick inquiry Where to buy Suppliers range | Glycogen phosphorylase inhibitor is a cell-permeable inhibitor of human liver glycogen phosphorylase with an IC50 value of 53 nM. It has been used in biological studies to study glycogen utilization in human liver HepG2 cells, retinal explants, and human T lymphocyte Kit 225 cells. Synonyms: GPI; 2-chloro-4, 5-difluoro-N- [ [ [2-methoxy-5- [ [ (methylamino) carbonyl] amino] phenyl] amino] carbonyl] -benzamide. Grades: ≥98%. CAS No. 648926-15-2. Molecular formula: C17H15ClF2N4O4. Mole weight: 412.8. | |
Glycogen Phosphorylase Inhibitor Quick inquiry Where to buy Suppliers range | Glycogen Phosphorylase Inhibitor is used in biological studies to to evaluate glycogen utilization in human liver HepG2 cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 648926-15-2. Pack Sizes: 1mg, 5mg. Molecular Formula: C17H15ClF2N4O4, Molecular Weight: 412.78. US Biological Life Sciences. | Worldwide |
NUCLEOSIDE PHOSPHORYLASE Quick inquiry Where to buy Suppliers range | NUCLEOSIDE PHOSPHORYLASE. Uses: Used for research and manufacturing. Group: Food Ingredients. Alternative Names: Nucleoside Phosphorylase bacterial,PNP, Purine nucleoside phosphorylase, Purine nucleoside:orthophosphate ribosyltransferase;Purine nucleoside phosphorylase [ >=200 units/mg];Deoxyribonucleoside phosphorylase;Purine deoxynucleoside phosphorylase;Purine deoxyribonucleoside phosphorylase;Purine ribonucleoside phosphorylase;PNP/Purine-nucleoside phosphorylase;Nucleoside Phosphorylase from microorganisms. CAS No. 9030-21-1. Pack Sizes: 1 kg. Product ID: CDF4-0059. | |
1,1-Diphenyldiazomethane Quick inquiry Where to buy Suppliers range | 1,1-Diphenyldiazomethane is used to synthesize tartaric acid analogs of FR258900 as glycogen phosphorylase inhibitors. Group: Biochemicals. Alternative Names: Diazodiphenylmethane; Diphenylazomethane; Diphenyldiazomethane. Grades: Highly Purified. CAS No. 883-40-9. Pack Sizes: 1g, 2.5g, 10g. Molecular Formula: C??H??N?, Molecular Weight: 194.23. US Biological Life Sciences. | Worldwide |
1,2,3,4,6-Penta-O-acetyl-5-thio-D-glucose Quick inquiry Where to buy Suppliers range | Penta-O-acetyl-5-thio-D-glucose (PATG) - a name that resonates with power and inhibition. This scientific marvel, also known as an effective inhibitor of glycogen phosphorylase, holds immense potential in the treatment of type 2 diabetes. But its role transcends the medical realm - PATG can serve as a vital tool in delving deeper into the intricate workings of glucose homeostasis and glycogen metabolism. Buckle up and welcome the perplexity and burstiness of this immaculate compound. Synonyms: (3,4,5,6-tetraacetyloxythian-2-yl)methyl acetate; Acetyl-2,3,4,6-tetra-O-acetyl-5-thio-d-glucopyranoside; 5-Thio-D-glucopyranose 1,2,3,4,6-pentaacetate; RFPPVTQRDZKNPS-UHFFFAOYSA-N; BCP29954; MFCD18086932; SY344742; 6-(Acetoxymethyl)tetrahydro-2H-thiopyran-2,3,4,5-tetrayl (3R,4S,5S,6R)-Tetraacetate; 1,2,3,4,6-Penta-O-acetyl-5-thio-D-glucopyranose pound>>Penta-O-acetyl-5-thio-D-glucopyranose. CAS No. 10470-80-1. Molecular formula: C16H22O10S. Mole weight: 406.41. | |
1,4-Dideoxy-1,4-imino-D-arabinitol hydrochloride Quick inquiry Where to buy Suppliers range | 1,4-Dideoxy-1,4-imino-D-arabinitol Hydrochloride is a potential inhibitor of glycogen decomposition and glycogen phosphorylase. Synonyms: (2R,3R,4R)-3,4-Dihydroxy-2-(hydroxymethyl)pyrrolidine Hydrochloride; DAB-1 Hydrochloride; 3,4-pyrrolidinediol, 2-Hydroxymethyl-, hydrochloride, [2R-(2α,3β,4α)]-. Grades: ≥98%. CAS No. 100991-92-2. Molecular formula: C5H11NO3.HCl. Mole weight: 169.61. | |
1,5-Anhydro-4,6-O-benzylidene-D-glucitol Quick inquiry Where to buy Suppliers range | 1,5-Anhydro-4,6-O-benzylidene-D-glucitol is a compound primarily used in biomedical research related to diabetes. It serves as a precursor in the synthesis of C-glycoside analogs, which are investigated as inhibitors of glycogen phosphorylase, a target enzyme for type 2 diabetes. Synonyms: 2,6-Anhydro-1,3-O-benzylidenehexitol. CAS No. 65190-39-8. Molecular formula: C13H16O5. Mole weight: 252.26. | |
1-Azido-1-deoxy-β-D-glucopyranoside tetraacetate Quick inquiry Where to buy Suppliers range | 1-Azido-1-deoxy-β-D-glucopyranoside tetraacetate (CAS# 13992-25-1) is an intermediate used for the synthesis of Protein Tyrosine Phosphatase 1B inhibito1. It is used for the preparation of variously coupled conjugates of D-glucose via click chemistry for inhibition of glycogen phosphorylase. Synonyms: 2,3,4,6-Tetra-O-acetyl-1-deoxy-β-D-glucopyranosyl azide; β-D-Glucopyranosyl Azide 2,3,4,6-Tetraacetate; 1-β-Azido-2,3,4,6-tetraacetyl-D-glucopyranose; 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl azide; NSC 272456; 1-Azido-1-deoxy-beta-D-glucopyranose tetraacetate; (2R,3R,4S,5R,6R)-2-(Acetoxymethyl)-6-azidotetrahydro-2H-pyran-3,4,5-triyl triacetate. Grades: ≥95%. CAS No. 13992-25-1. Molecular formula: C14H19N3O9. Mole weight: 373.32. | |
1H-?Pyrrolo[2,?3-?b]?pyridin-?1-?ylacetic Acid Quick inquiry Where to buy Suppliers range | 1H-?Pyrrolo[2,?3-?b]?pyridin-?1-?ylacetic Acid is an analog of 7-Azaindole and can be used as a novel inhibitor of glycogen phosphorylase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1048913-13-8. Pack Sizes: 25mg, 50mg. Molecular Formula: C9H8N2O2, Molecular Weight: 176.17. US Biological Life Sciences. | Worldwide |
2,2-Dimethyl-1,3-dioxolane-4-methanol 4-Methanesulfonate-d5 Quick inquiry Where to buy Suppliers range | Used in the preparation of N-heterocyclic indole carboxamides as glycogen phosphorylase inhibitors. Group: Biochemicals. Alternative Names: 2,2-Dimethyl-1,3-dioxolane-4-methanol 4-Methanesulfonate-d5; (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl Methanesulfonate-d5; (±)-1,2-O-Isopropylidenepropane-1,2,3-triol 3-Mesylate-d5; DL-1-Methane sulfonylisopropyl idene glycerol-d5; Solketal Mesylate-d5. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
2-(2-Nitroanilino)ethanol Quick inquiry Where to buy Suppliers range | 2-(2-Nitroanilino)ethanol is used in the preparation of (phenylamino) quinoxalinone derivatives which has been identified as a new class of glycogen phosphorylase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 4926-55-0. Pack Sizes: 250mg, 5g. Molecular Formula: C8H10N2O3. US Biological Life Sciences. | Worldwide |
2-(2-Nitroanilino)ethanol-d4 Quick inquiry Where to buy Suppliers range | 2-(2-Nitroanilino)ethanol-d4 is the isotope analog of 2-(2-Nitroanilino)ethanol. 2-(2-Nitroanilino)ethanol is used in the preparation of (phenylamino) quinoxalinone derivatives which has been identified as a new class of glycogen phosphorylase inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 250mg. Molecular Formula: C8H6D4N2O3, Molecular Weight: 186.2. US Biological Life Sciences. | Worldwide |
2,3,5-Tri-O-acetyl Guanosine-13C2,15N Quick inquiry Where to buy Suppliers range | 2,3,5-Tri-O-acetyl Guanosine-13C2,15N is an intermediate in the synthesis of 8-Aminoguanosine-13C2,15N (A609877). 8-Aminoguanosine-13C2,15N is an isotopic labelled compound of 8-Aminoguanosine (A609875), which is a potent inhibitor of purine nucleoside phosphorylase. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C1413C2H19N415NO8. US Biological Life Sciences. | Worldwide |
2-Amino-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one Quick inquiry Where to buy Suppliers range | 9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd=160 nM). Synonyms: 2-amino-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one; 2-amino-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one. Grades: > 97 %. CAS No. 65996-58-9. Molecular formula: C6H6N4O. Mole weight: 150.14. | |
2-Benzylthioadenosine Quick inquiry Where to buy Suppliers range | 2-Benzylthioadenosine, a formidable inhibitor of methylthioadenosine phosphorylase (MTAP) - an enzyme primarily involved in adenine and methionine salvage - has received significant attention due to its potential contributions to the management of cancer forms denuded of MTAP expression (like pancreatic cancer or mesothelioma) as well as auto-immune illnesses and inflammation. Synonyms: (2R,3R,4S,5R)-2-(6-amino-2-(benzylthio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 2-(Benzylsulfanyl)adenosine; Adenosine, 2-[(phenylmethyl)thio]-. Grades: ≥95%. CAS No. 43157-48-8. Molecular formula: C17H19N5O4S. Mole weight: 389.43. | |
2-Fluoroadenine Quick inquiry Where to buy Suppliers range | A purine nucleoside phosphorylase gene therapy for human malignancy. Group: Biochemicals. Alternative Names: 2-Fluoro-9H-purin-6-amine; 2-Fluoro-1H-purin-6-amine; 2-Fluoro-adenine; 2-Fluoro-6-aminopurine; NSC 27364. Grades: Highly Purified. CAS No. 700-49-2. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
3',5'-Di-O-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-O-methyluridine Quick inquiry Where to buy Suppliers range | 3',5'-Di-O-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2'-O-methyluridine is a derivative of 6-Methyluridine, which is an exhibited weak antimalarial activity against P. falciparum 3D7 isolate. It is a weak substrate of Escherichia coli pyrimidine nucleoside phosphorylase. Synonyms: 5-Fluoro-4-O-(2,4,6-trimethylphenyl)-2',3',5'-triacetate Uridine. CAS No. 869355-32-8. Molecular formula: C23H27FN2O8. Mole weight: 478.47. | |
3-Amino-3,4-dihydroquinolin-2(1H)-one Quick inquiry Where to buy Suppliers range | 3-Amino-3,4-dihydroquinolin-2(1H)-one is an intermediate used to prepare thienopyrroles as glycogen phosphorylase inhibitors. It is also an impurity of Melphalan (M216900). Group: Biochemicals. Grades: Highly Purified. CAS No. 40615-17-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H10N2O, Molecular Weight: 162.19. US Biological Life Sciences. | Worldwide |
3-Amino-6-bromobiphenyl Quick inquiry Where to buy Suppliers range | 3-Amino-6-bromobiphenyl is used as a reactant in the preparation of chloro aryl indolecarboxamide derivatives as inhibitors of human liver glycogen phosphorylase a. Also used in synthesis of large and stable colloidal graphene quantum dots with tunable size. Group: Biochemicals. Grades: Highly Purified. CAS No. 1036750-83-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C12H10BrN, Molecular Weight: 248.12. US Biological Life Sciences. | Worldwide |
3'-β-Thymidine Quick inquiry Where to buy Suppliers range | As an intermediate in the production of fluorothymidine and phosphorylase derivatives 3'-β-Thymidine (Stavudine EP Impurity B) is used as an antiviral agent. Reverse transcriptase inhibitor. Synonyms: 1-(2-Deoxy-β-D-threo-pentofuranosyl)-5-methyluricil; 1-(2-Deoxy-b-D-xylofuranosyl)-5-methyluracil; 1-(2-Deoxy-β-D-threo-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-(2-Deoxy-β-D-threo-pentofuranosyl)-thymine; NSC 526738; Stavudine EP Impurity B; 1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione. Grades: ≥95%. CAS No. 16053-52-4. Molecular formula: C10H14N2O5. Mole weight: 242.23. | |
3'-Deoxyguanosine Quick inquiry Where to buy Suppliers range | 3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors. Synonyms: 2-Amino-9-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 3'-Deoxy-D-guanosine; 9-(3-Deoxy-β-D-erythro-pentofuranosyl)-Guanine; 2-amino-9-(3-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-ol. Grades: ≥95%. CAS No. 3608-58-0. Molecular formula: C10H13N5O4. Mole weight: 267.24. | |
3-epi-Ursolic Acid Quick inquiry Where to buy Suppliers range | 3-epi-Ursolic Acid is a potent inhibitor against glycogen phosphorylase which makes it a potential rug for treatment of type-2 diabetes and other diseases associated with glycogen metabolism. It is also a part of the group of triterpenoids that act as novel inhibitors of Human Cathepsin L. Group: Biochemicals. Grades: Highly Purified. CAS No. 989-30-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C30H48O3, Molecular Weight: 456.7. US Biological Life Sciences. | Worldwide |
4-Nitrophenyl b-D-ribofuranoside Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl b-D-ribofuranoside, a complex biochemical reagent utilized in laboratory settings as a substrate in the detection of numerous enzymes with which it imperatively interacts. The composition is particularly central to assays of phosphoribosylpyrophosphate synthetase, nucleoside phosphorylase, and ribosyltransferases, and is also highly effective in synthesizing nucleotides and nucleosides for further biochemical analysis. Synonyms: PNP-b-D-riboside. CAS No. 59495-69-1. Molecular formula: C11H13NO7. Mole weight: 271.22. | |
4-Nitrophenyl N,N-diacetyl-b-D-chitobioside Quick inquiry Where to buy Suppliers range | 4-Nitrophenyl N,N-diacetyl-b-D-chitobioside is a versatile compound widely used in the biomedical industry. This product plays a crucial role in enzyme assays, as it acts as a substrate for chitobiose phosphorylase. It enables the detection and quantification of this enzyme, making it invaluable in disease research and drug development related to chitobiose metabolism. Synonyms: 4-Nitrophenyl 2-acetamido-2-deoxy-(4-O-2-acetamido-2-deoxy-b-D-glucopyranosyl)-b-D-glucopyranoside. CAS No. 7284-16-4. Molecular formula: C22H31N3O13. Mole weight: 545.49. | |
5-(2-Furanyl)-2-deoxyuridine Quick inquiry Where to buy Suppliers range | Several novel 5-substituted 2'-deoxyuridine (dUrd) analogs were evaluated as substrates for highly purified herpes simplex virus type 1 (HSV-1)-encoded thymidine kinase (TK) derived from HSV-1 TK gene-transfected murine mammary carcinoma FM3A cells, and human platelet thymidine (dThd) phosphorylase. Group: Biochemicals. Alternative Names: 2'-Deoxy-5-(2-furanyl)uridine. Grades: Highly Purified. CAS No. 92233-50-6. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
5-Chloro-6-[(2-Oxo-1-Pyrrolidinyl)Methyl]-2,4(1H,3H)-Pyrimidinedione Quick inquiry Where to buy Suppliers range | One of the impurities of Tipiracil, which is a thymidine phosphorylase (TPase) inhibitor and has been found to be a potential drug candidate for metastatic colorectal cancer. Synonyms: Tipiracil Impurity C. Grades: ≥95%. CAS No. 2101241-71-6. Molecular formula: C9H12ClN3O3. Mole weight: 245.66. | |
5-Iodouracil Quick inquiry Where to buy Suppliers range | 5-Iodouracil is a halogenated pyrimidine that can be used in nucleoprotein photo-crosslinking via RNA substitution. 5-Iodouracil is used in thymidine phosphorylase targeted imaging and therapy. Studies show that DNA N-glycosylase MED1 exhibited higher preference for 5-Iodouracil and halogenated bases over non-halogenated ones. Group: Biochemicals. Alternative Names: 5-Iodo-2,4(1H,3H)-pyrimidinedione; 5-Iodo-2,4-dihydroxypyrimidine; 5-Iodo-2,4-pyrimidinedione; 5-Iodopyrimidine-2,4-diol; 5-Iodouracil; NSC 57848. Grades: Highly Purified. CAS No. 696-07-1. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
5'-O-Tritylinosine Quick inquiry Where to buy Suppliers range | KIN59 is a purine riboside derivative that suppresses thymidine phosphorylase (TPase). TPase is an enzyme catalyzing the reversible phosphorolysis of pyrimidine deoxynucleosides to 2-deoxy-d-ribose-1-phosphate and their respective pyrimidine bases. KIN59 noncompetitively inhibits TPase-induced angiogenesis in the chorioallantoic membrane assay. Synonyms: 5'-Trt-rI; (2R,3R,4S,5R)-9-(3,4-Dihydroxy-5-trityloxymethyl-tetrahydrofuran-2-yl)-1,9-dihydropurin-6-one; KIN-59; Inosine, 5'-O-(triphenylmethyl)-; 5'-O-(triphenylmethyl)-inosine. Grades: ≥98% by HPLC. CAS No. 4152-77-6. Molecular formula: C29H26N4O5. Mole weight: 510.55. | |
5-(Trimethylstannyl)-2'-deoxyuridine Quick inquiry Where to buy Suppliers range | Several novel 5-substituted 2'-deoxyuridine analogs were evaluated as substrates for highly purified herpes simplex virus type 1 (HSV-1)-encoded thymidine kinase (TK), which derived from HSV-1 TK gene-transfected murine mammary carcinoma FM3A cells, and human platelet thymidine (dThd) phosphorylase. Uses: Several novel 5-substituted 2'-deoxyuridine (durd) analogs were evaluated as substrates for highly purified herpes simplex virus type 1 (hsv-1)-encoded thymidine kinase (tk) derived from hsv-1 tk gene-transfected murine mammary carcinoma fm3a cells, and h. Synonyms: 2'-Deoxy-5-(trimethylstannyl)uridine. Grades: 97%. CAS No. 146629-34-7. Molecular formula: C12H20N2O5Sn. Mole weight: 391.01. | |
6-[(2-Imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione Quick inquiry Where to buy Suppliers range | One of the impurities of Tipiracil, which is a thymidine phosphorylase (TPase) inhibitor and has been found to be a potential drug candidate for metastatic colorectal cancer. Synonyms: Tipiracil Impurity des Cl. Grades: ≥95%. CAS No. 2069937-25-1. Molecular formula: C9H12N4O2. Mole weight: 208.22. | |
6-Benzylamino-9-(2'-deoxy-b-D-ribofuranosyl)purine Quick inquiry Where to buy Suppliers range | 6-Benzylamino-9-(2'-deoxy-b-D-ribofuranosyl)purine, known for its potent antiviral properties, serves as an essential nucleoside analog in the field of biomedicine. Aiming to combat purine nucleoside phosphorylase (PNP)-deficient T-cell leukemias, this compound showcases remarkable efficacy. Furthermore, its therapeutic potential extends to viral infections like HIV and herpes. As a pharmacological tool, this compound holds immense value in investigating PNP-related diseases and delving into potential therapeutic strategies. Synonyms: N-Benzyl-2'-deoxyadenosine; n6-benzyl-2'-deoxyadenosine; 2'-Deoxy-N6-benzyladenosine; 6-Benzylamino-9-(2'-deoxy-b-D-ribofuranosyl)purine. Molecular formula: C17H19N5O3. Mole weight: 341.36. | |
6-Chloro-3,4-pyridinediamine Quick inquiry Where to buy Suppliers range | 6-chloro-3,4-pyridinediamine, 89182-17-2, 6-chloropyridine-3,4-diamine, 9030-21-1, nucleoside phosphorylase, 3,4-DIAMINO-6-CHLOROPYRIDINE, 4,5-Diamino-2-chloropyridine, 3,4-Pyridinediamine, 6-chloro-, MFCD04037269, 2-Chloro-4,5-diaminopyridine, 6-Chloro-3,4-diaminepyridine, 6-Chloro-3,4-diaminopyridine, 6-chloro-pyridine-3,4-diamine, Inosine phosphorylase, 2604-40-2, SCHEMBL191846, Inosine-guanosine phosphorylase, Phosphorylase, purinenucleoside, Phosphorylase, purine nucleoside, DTXSID70920468, BCP14452, EINECS 232-857-3, AKOS006335389, CS-W003135, PB14373, PS-5607, AC-26686, SY029809, AM20061836, FT-0649236, E.C. 2.4.2.1, J-518651. | |
7-Deaza-2'-deoxyadenosine Quick inquiry Where to buy Suppliers range | It is a purine nucleoside phosphorylase inhibitor. Synonyms: 4-Amino-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 2'-Deoxytubercidin; Deoxytubercidin; 7-Deazadeoxyadenosine; (2R,3S,5R)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 2'-deoxy-7-deazaadenosine. Grades: ≥95%. CAS No. 60129-59-1. Molecular formula: C11H14N4O3. Mole weight: 250.25. | |
7-Oxo staurosporine Quick inquiry Where to buy Suppliers range | 7-Oxo staurosporine is an antibiotic originally isolated from S. platensis with diverse biological activites. It inhibits PKC, PKA, phosphorylase kinase, EGFR, and c-Src in vitro (IC50s = 9, 26, 5, 200, and 800 nM, respectively). Synonyms: BMY 41950; RK-1409; 7-oxostaurosporine. Grades: ≥98%. CAS No. 125035-83-8. Molecular formula: C28H24N4O4. Mole weight: 480.5. | |
8-Aminoguanosine Quick inquiry Where to buy Suppliers range | A potent inhibitor of purine nucleoside phosphorylase. Uses: A potent inhibitor of purine nucleoside phosphorylase. Synonyms: 2,8-Diaminoinosine; NSC 90390. Grades: 98%. CAS No. 3868-32-4. Molecular formula: C10H14N6O5. Mole weight: 298.26. | |
8-Aminoguanosine (2,8-Diaminoinosine) Quick inquiry Where to buy Suppliers range | A potent inhibitor of purine nucleoside phosphorylase. Group: Biochemicals. Alternative Names: 2,8-Diaminoinosine. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
8-Aza-5'-AMP Quick inquiry Where to buy Suppliers range | 8-Aza-5'-AMP, a nucleoside analog, has been widely employed in exploring the activity of purine nucleoside phosphorylase (PNP) and its role in immune system functionality. Moreover, it maintains immense potential for conducting experiments on T-cell depletion and treating severe ailments like autoimmune diseases and cancer. Synonyms: 8- Azaadenosine- 5'- O- monophosphate. Molecular formula: C9H13N6O7P (free acid). Mole weight: 348.2 (free acid). | |
8-Azaguanosine Quick inquiry Where to buy Suppliers range | It is a substrate of purine nucleoside phosphorylase (PNP)?. Synonyms: Azaguanosine; NSC 46788; NSC 130283; 7H-1,2,3-Triazolo(4,5-d)pyrimidin-7-one, 5-amino-3,4-dihydro-3-beta-D-ribofuranosyl-; 5-Amino-3,6-dihydro-3-β-D-ribofuranosyl-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one. Grades: ≥95%. CAS No. 2133-80-4. Molecular formula: C9H12N6O5. Mole weight: 284.23. | |
9-Deazaguanine Quick inquiry Where to buy Suppliers range | A nucleoside analog as potent inhibitor of purine nucleoside phosphorylase. Group: Biochemicals. Alternative Names: 2-Amino-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one; NSC 344522. Grades: Highly Purified. CAS No. 65996-58-9. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
α-D-Glucosamine 1-Phosphate Quick inquiry Where to buy Suppliers range | A phosphorylated glucosamine used in the enzymatic α-glucosaminylation of maltooligosaccharides catalyzed by phosphorylase. Synonyms: 2-Amino-2-deoxy-α-D-glucopyranose 1-(dihydrogen phosphate); 2-Amino-2-deoxy-α-D-glucopyranosyl Phosphate. CAS No. 2152-75-2. Molecular formula: C6H14NO8P. Mole weight: 259.15. | |
α-D-Mannose 1-Phosphate Quick inquiry Where to buy Suppliers range | α-D-Mannose 1-Phosphate is used in the synthesis of non-natural mannoglucans by α-glucan phosphorylase-catalyzed enzymatic copolymerization;Also, it is derived from D-Mannose, which is a carbohydrate that is important in the glycosylation of molecules in a variety of cellular processes. It is involved in N and O glycosylation of bovine why protein products, used in infant formulas. It is also responsible for the O-glycosylation of the T helper cell-derived cytokine interlukin-17A, an important cell-signaling molecule. Synonyms: D-Mannose 1-Phosphate; α-D-Mannopyranosyl Phosphate; α-D-Mannopyranose 1-(Dihydrogen Phosphate). CAS No. 15978-07-1. Molecular formula: C6H13O9P. Mole weight: 260.14. | |
CI 972 Quick inquiry Where to buy Suppliers range | This active molecular is a potent purine nucleoside phosphorylase inhibitor and a T cell-selective immunosuppressive agent. CI-972 inhibited proliferation of human MOLT-4 (T cell) and not MGL-8 (B cell) lymphoblasts with respective IC50s of 3.0 and greater than 50 microM when tested with 10 microM 2'-deoxyguanosine. In Apr 1996, Immunological Disorders section added to drug profile and Immunological disorders in USA was discontinued. Uses: Immunological disorders; transplant rejection. Synonyms: CI 972; CI972; CI-972. 4H-Pyrrolo(3,2-d)pyrimidin-4-one, 2,6-diamino-1,5-dihydro-7-(3-thienylmethyl)-, monohydrochloride. Grades: 98%. CAS No. 115787-68-3. Molecular formula: C11H12ClN5OS. Mole weight: 297.76. | |
CP 316819 Quick inquiry Where to buy Suppliers range | CP 316819 has been found to be a glycogen phosphorylase inhibitor and could probably be used in the treatment for glycemic control in type 2 diabetes. Synonyms: CP 316819; CP316819; CP-316819; 5-Chloro-N-[(1S,2R)-2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide. Grades: ≥98% by HPLC. CAS No. 186392-43-8. Molecular formula: C21H22ClN3O4. Mole weight: 415.87. | |
CP-316819 Quick inquiry Where to buy Suppliers range | A novel glycogen phosphorylase inhibitor; potential treatment for glycemic control in type 2 diabetes. Group: Biochemicals. Alternative Names: 5-Chloro-N-[(1S,2R)-2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide; GPi 819; CP 316 819. Grades: Highly Purified. CAS No. 186392-43-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
CP-320626 Quick inquiry Where to buy Suppliers range | CP-320626, a carboxamide derivative, is a potent glycogen phosphorylase inhibitor and a possible target for type 2 diabetes therapy. CP-320626 is also a potent inhibitor of human muscle GPa. Synonyms: 5-chloro-N-[(2S)-3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide;CP-320626; CP320626; CP 320626. Grades: >98%. CAS No. 186430-23-9. Molecular formula: C23H23ClFN3O3. Mole weight: 443.90. | |
CP-91149 Quick inquiry Where to buy Suppliers range | Inhibition of glycogen phosphorylase (GP) by CP-91,149 induces growth inhibition correlating with brain GP expression. Antitumor agent. Group: Biochemicals. Alternative Names: 5-Chloro-N-[(1S,2R)-3-(dimethylamino)-2-hydroxy-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide; [R-(R*,S*)]-5-Chloro-N-[3-(dimethylamino)-2-hydroxy-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide; CP 91149. Grades: Highly Purified. CAS No. 186392-40-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
CP-91149 Quick inquiry Where to buy Suppliers range | CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose. Synonyms: CP 91149; CP91149; 5-Chloro-1H-indole-2-carboxylic acid ((1S,2R)-1-benzyl-2-dimethylcarbamoyl-2-hydroxy-ethyl)-amide. Grades: >98%. CAS No. 186392-40-5. Molecular formula: C21H22ClN3O3. Mole weight: 399.87. | |
Etheno-2-deoxy- β-D-adenosine 5-Monophosphate Quick inquiry Where to buy Suppliers range | A phosphorylated adenosine derivative used as probes of the activator site of glycogen phosphorylase. It is used in method for detecting misincorporation during DNA synthesis. Group: Biochemicals. Alternative Names: 3-(2-Deoxy-5-O-phosphono- β-D-erythro-pentofuranosyl)-3H-imidazo[2,1-i]purine; 1,N6-Etheno-2'-deoxy-AMP. Grades: Highly Purified. CAS No. 60508-81-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Forodesine Quick inquiry Where to buy Suppliers range | Forodesine, also known as BCX-1777, is the hydrochloride salt of the synthetic high-affinity transition-state analogue forodesine. Forodesine binds preferentially to and inhibits purine nucleotide phosphorylase (PNP), resulting in the accumulation of deoxyguanosine triphosphate and the subsequent inhibition of the enzyme ribonucleoside diphosphate reductase and DNA synthesis. This agent selectively causes apoptosis in stimulated or malignant T-lymphocytes. A transition state analogue is a substrate designed to mimic the properties or the geometry of the transition state of reaction. Synonyms: Immucillin-H hydrochloride; Forodesine. Grades: 98%. CAS No. 209799-67-7. Molecular formula: C11H14N4O4. Mole weight: 266.25. | |
Forodesine hydrochloride Quick inquiry Where to buy Suppliers range | Forodesine hydrochloride is the hydrochloride salt of Forodesine. Forodesine, also called as BCX-1777 or Immucillin-H, is an orally bioavailable inhibior of mammalian purine nucleoside phosphorylase (PNP). Forodesine is undergoing a phase II trial to trea. Synonyms: 7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one;hydrochloride1-(9-deazahypoxanthin-9-yl)-1,4-dideoxy-1,4-iminoribitolBCX-1777; BCX1777BCX1777forodesineImmH cpdimmucillin Himmucillin-H. CAS No. 284490-13-7. Molecular formula: C11H15ClN4O4. Mole weight: 302.715. | |
GPi 688 Quick inquiry Where to buy Suppliers range | GPi 688 is an allosteric glycogen phosphorylase inhibitor that inhibits glucagon-mediated hyperglycemia in the rat. Synonyms: GPi 688; GPi688; GPi-688; 2-Chloro-N-[1-[(2R)-2,3-dihydroxypropyl]-1,2,3,4-tetrahydro-2-oxo-3-quinolinyl]-6H-thieno[2,3-b]pyrrole-5-carboxamide. Grades: ≥99% by HPLC. CAS No. 918902-32-6. Molecular formula: C19H18ClN3O4S. Mole weight: 419.88. | |
Ingliforib Quick inquiry Where to buy Suppliers range | Ingliforib, with antihyperglycemic and cardioprotective properties, inhibits glycogen phosphorylase. Synonyms: Ingliforib; CP-296; CP-368; CP-368,296; CP296; CP 296; CP-368296; CP368296; CP 368296; 5-chloro-N-[(2S,3R)-4-[(3S,4R)-3,4-dihydroxypyrrolidin-1-yl]-3-hydroxy-4-oxo-1-phenylbutan-2-yl]-1H-indole-2-carboxamide; 5-Chloro-N-((1S,2R)-3-((3R,4S)-3,4-dihydroxy-1-pyrrolidinyl))-2-hydroxy-3-oxo-1-(phenylmethyl)propyl-1H-indole-2-carboxamide. Grades: >98%. CAS No. 186392-65-4. Molecular formula: C23H24ClN3O5. Mole weight: 457.91. | |
K-252a Quick inquiry Where to buy Suppliers range | K-252a is an antibiotic, PKC, PKA and PKG inhibitor. Shows neurotropic activity by inducing neurite outgrowth. Highly potent cell permeable CaM kinase and phosphorylase inhibitor. Tyrosine protein kinase inhibitor of the TRK family. Antiproliferative and apoptosis inducer. Cell cycle arrest inducer. Potential drug for psoriasis treatment. Source:Isolated from Nonomuraea longicatena chiba. Group: Biochemicals. Grades: Highly Purified. CAS No. 99533-80-9. Pack Sizes: 100ug, 1mg. Molecular Formula: C27H21N3O5. US Biological Life Sciences. | Worldwide |
Leukadherin-1 Quick inquiry Where to buy Suppliers range | Leukadherin-1, also known as LA1, is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion to its ligand ICAM-1. Leukadherin-1 suppresses human innate inflammatory signalling. leukadherin-1 increases CD11b/CD18-dependent adhesion via membrane tethers. It also competitively inhibits YopH (Ki = 1.94 μM), a tyrosine phosphorylase secreted by Y. pestis into immune cells to block signal transduction, and anthrax lethal factor metalloproteinase, a component of anthrax toxin (IC50 = 6 μM). Synonyms: 4-[5-[[4-Oxo-3-(phenylmethyl)-2-thioxo-5-thiazolidinylidene]methyl]-2-furanyl]-benzoic acid; Leukadherin-1; Leukadherin 1; Leukadherin1; LA1. CAS No. 344897-95-6. Molecular formula: C22H15NO4S2. Mole weight: 421.48. | |
Malantide Quick inquiry Where to buy Suppliers range | Malantide, a highly specific substrate for PKA, is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Synonyms: H-Arg-Thr-Lys-Arg-Ser-Gly-Ser-Val-Tyr-Glu-Pro-Leu-Lys-Ile-OH; L-arginyl-L-threonyl-L-lysyl-L-arginyl-L-seryl-glycyl-L-seryl-L-valyl-L-tyrosyl-L-alpha-glutamyl-L-prolyl-L-leucyl-L-lysyl-L-isoleucine. Grades: ≥95%. CAS No. 86555-35-3. Molecular formula: C72H124N22O21. Mole weight: 1633.89. | |
Malantide acetate Quick inquiry Where to buy Suppliers range | Malantide acetate, a highly specific substrate for PKA, is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Synonyms: H-Arg-Thr-Lys-Arg-Ser-Gly-Ser-Val-Tyr-Glu-Pro-Leu-Lys-Ile-OH.CH3CO2H; L-arginyl-L-threonyl-L-lysyl-L-arginyl-L-seryl-glycyl-L-seryl-L-valyl-L-tyrosyl-L-alpha-glutamyl-L-prolyl-L-leucyl-L-lysyl-L-isoleucine acetic acid. Grades: ≥95%. Molecular formula: C74H128N22O23. Mole weight: 1693.97. | |
MTDIA Quick inquiry Where to buy Suppliers range | MTDIA is a human 5'-methylthioadenosine phosphorylase (MTAP) inhibitor, which is solely responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. It is used as an anticancer candidate. Synonyms: Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium. Grades: 98%. CAS No. 653592-04-2. Molecular formula: C13H19N5OS. Mole weight: 294.35. | |
MTDIA hydrochloride Quick inquiry Where to buy Suppliers range | MTDIA is a methylthioadenosine phosphorylase (MTAP) inhibitor. MTAP is responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. Transition-state (TS) analogues of MTAP are in development as anticancer drug candidates and MTDIA is one of these TS analogues. Uses: Anticancer drug candidate. Synonyms: (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium chloride; MTDIA; MTDIA HCl; Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; MT-DADMe-ImmA HCl. Grades: 98%. CAS No. 1399840-35-7. Molecular formula: C13H20ClN5OS. Mole weight: 329.85. | |
N-Acetyl-guanosine 2',3',5'-Triacetate 6-(N,N-Diphenylcarbamate) Quick inquiry Where to buy Suppliers range | N-Acetyl-guanosine 2',3',5'-Triacetate 6-(N,N-Diphenylcarbamate) is an intermediate in the synthesis of 8-Aminoguanosine. 8-Aminoguanosine is a potent inhibitor of purine nucleoside phosphorylase. Synonyms: N-Acetyl-guanosine 2',3',5'-Triacetate 6-(Diphenylcarbamate). CAS No. 112233-75-7. Molecular formula: C31H30N6O10. Mole weight: 646.6. | |
pdGp Quick inquiry Where to buy Suppliers range | pdGp, also known as pyruvate dehydrogenase kinase, is a remarkably efficacious and highly targeted inhibitor of the glycogen phosphorylase (Gp). Synonyms: 2'- Deoxyguanosine- 3', 5'- O- bisphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 16174-59-7. Molecular formula: C10H15N5O10P2. Mole weight: 427.2. | |
Staurosporin Quick inquiry Where to buy Suppliers range | Staurosporine is an alkaloid isolated from the culture broth of Streptomyces staurospores and is a super-potent, cell permeable PKC inhibitor (IC50=0.7); at higher concentrations Staurosporine inhibits other protein kinases: CDK2/cyclin A (IC50=7uM) and CDK4/cyclin D (IC50=3-10uM). At a concentration of 50-100nM it is a functional neurotrophins agonist promoting neurite outgrowth in neuroblastoma, pheochromocytoma and brain primary neuronal cultures. Staurosporine inhibits a variety of kinases including PKA, PKG, MLCK, CaMK, tyrosine kinases, and phosphorylase kinase. This compound displays selectivity toward the PKC isoforms, inhibiting PKCα, PKC β, PKCγ, PKCδ, and PKCε, but not PKC?, and induces PKC translocation. Staurosporine also inhibits topoisomerase II directly by interaction with the ATP binding site, augments PMA-induced ornithine decarboxylase, and activates a bcl-2-regulated apoptosis pathway. Source:Streptomyces staurosporeus. Group: Biochemicals. Alternative Names: Antibiotic AM2282; Antibiotic 230; CCRIS 3272. Grades: Highly Purified. CAS No. 62996-74-1. Pack Sizes: 100ug, 1mg, 5mg, 10mg. Molecular Formula: C28H26N4O3, Molecular Weight: 466.53. US Biological Life Sciences. | Worldwide |
TAS-102 Quick inquiry Where to buy Suppliers range | TAS-102 is a combination drug composed of the cytotoxic pyrimidine analog Trifluridine (5-trifluoro-2'-deoxythymidine or TFT) and a thymidine phosphorylase inhibitor (TPI) tipiracil hydrochloride, in a molar ratio of 1.0:0.5 (TFT:TPI). TAS-102 is used as a third- or fourth-line treatment of metastatic colorectal cancer. Synonyms: Tipiracil / Trifluridine; Viroptic mixture with 5-CIMU; TAS 102; EX-A1755; Tipiracil hydrochloride / Trifluridine. CAS No. 733030-01-8. Molecular formula: C9H11ClN4O2·HCl·C10H11F3N2O5. Mole weight: 575.328. | |
Tipiracil Quick inquiry Where to buy Suppliers range | Tipiracil, a thymidine phosphorylase (TPase) inhibitor, has been found to be a potential drug candidate for metastatic colorectal cancer. Synonyms: TAS-102; TAS102. CAS No. 183204-74-2. Molecular formula: C9H11ClN4O2. Mole weight: 242.67. | |
Tipiracil HCl Quick inquiry Where to buy Suppliers range | Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials. TAS-102 consists of the cytotoxin Trifluridine and the thymidine phosphorylase inhibitor (TPI) tipiracil. Trifluridine is incorporated into DNA during DNA synthesis and inhibits tumor cell growth. Tipiracil protects trifluridine from being broken down when taken orally. Synonyms: Tipiracil, TPI. Grades: 0.99. CAS No. 183204-72-0. Molecular formula: C9H12Cl2N4O2. Mole weight: 279.121. | |
Tipiracil Impurity 1 Quick inquiry Where to buy Suppliers range | One of the impurities of Tipiracil, which is a thymidine phosphorylase (TPase) inhibitor and has been found to be a potential drug candidate for metastatic colorectal cancer. Molecular formula: C9H10ClN3O3. Mole weight: 243.65. | |
Tipiracil Impurity 2 Quick inquiry Where to buy Suppliers range | One of the impurities of Tipiracil, which is a thymidine phosphorylase (TPase) inhibitor and has been found to be a potential drug candidate for metastatic colorectal cancer. Molecular formula: C6H7ClN2O3. Mole weight: 190.59. |