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| Product | Description | |
|---|---|---|
| Phthalazinone pyrazole | Phthalazinone pyrazole is a potent inhibitor of Aurora A kinase (IC50 = 31 nM). Phthalazinone pyrazole displays good pharmacological profiles with significantly improved oral bioavailability compared to the well studied Aurora inhibitor VX-680. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 880487-62-7. Molecular formula: C18H15N5O. Mole weight: 317.35. Purity: >98%. IUPACName: 4-((5-methyl-1H-pyrazol-3-yl)amino)-2-phenylphthalazin-1(2H)-one. Canonical SMILES: O=C1C2=C(C=CC=C2)C(NC3=NNC(C)=C3)=NN1C4=CC=CC=C4. Product ID: ACM880487627. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Phthalazinone pyrazole | Phthalazinone pyrazole is a potent, selective and orally bioavailable inhibitor of Aurora-A kinase. It was shown to arrest mitosis and inhibit tumor growth. Synonyms: 1(2H)-Phthalazinone, 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenyl-; 4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone; 4-[(5-Methyl-1H-pyrazol-3-yl)amino]-2-phenyl-2H-phthalazin-1-one. Grades: ≥98%. CAS No. 880487-62-7. Molecular formula: C18H15N5O. Mole weight: 317.35. |  |
| 2,5-Difluorobenzyl Bromide | 2,5-Difluorobenzyl Bromide is used as a reagent in the synthesis of phthalazinone pyrazoles as potent inhibitors of Aurora-A kinase. Also used as a reagent in the synthesis of 1,2,3,4-tetrahydropyrido[2,3-b]pyrazines as potent and selective inhibitors of the anaplastic lymphoma kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 85117-99-3. Pack Sizes: 1g, 10 g. Molecular Formula: C7H5BrF2, Molecular Weight: 207.02. US Biological Life Sciences. |  Worldwide |
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