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PHTPP PHTPP, a pyrazolo[1,5-α]pyrimidine-based ligand, is a selective estrogen ERβ receptor antagonist that displays 36-fold selectivity over ER&alpha. This compound has been used to selectively target ERβ in the study of the opposing effects of hormone therapy on tumors expressing either ER subtype. Synonyms: 4-[2-Phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenol. Grades: ≥99% by HPLC. CAS No. 805239-56-9. Molecular formula: C20H11F6N3O. Mole weight: 423.31. BOC Sciences 8
PHTPP Selective estrogen ER β receptor antagonist that displays 36-fold selectivity over ERα. Exhibits full antagonism at ER β in a cotransfection assay in human endometrial cancer cells (HEC-1), with minimal effects on ERα. Group: Biochemicals. Alternative Names: 4-[2-Phenyl-5, 7-bis (trifluoromethyl) pyrazolo[1, 5-a]pyrimidin-3-yl]phenol. Grades: Highly Purified. CAS No. 805239-56-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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