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Picoplatin Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AMD473; ZD0473. CAS No. 181630-15-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-131468. MedChemExpress MCE
Picoplatin Picoplatin is a new generation organic platinum analog with an extended spectrum of antineoplastic activity. Designed to overcome platinum drug resistance, picoplatin alkylates DNA, forming both inter- and intra-strand cross-linkages, resulting in inhibition of DNA replication and transcription, and the induction of apoptosis. Synonyms: AMD473; AMD 473; AMD-473; NX 473; NX473; NX-473; ZD0473; ZD 0473; ZD-0473. CAS No. 181630-15-9. Molecular formula: C6H10Cl2N2Pt. Mole weight: 376.15. BOC Sciences 9

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