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| Product | Description | |
|---|---|---|
| Picrotoxin (Cocculin) 98+% | Picrotoxin is a equimolar mixture of Picrotoxinin and Picrotin. It is a GABAA receptor antagonist and potent CNS stimulant. Group: Biochemicals. Alternative Names: Cocculin; (1aR, 2aR, 3S, 6R, 6aS, 8aS, 8bR, 9S) -Hexahydro-2a-hydroxy-9- (1-hydroxy-1-methylethyl) -8b-methyl-3, 6-methano-8H-1, 5, 7-trioxacyclopenta [ij]cycloprop [a]azulene-4, 8 (3H) -dione compd. with (1aR, 2aR, 3S, 6R, 6aS, 8aS, 8bR, 9R) -hexahydro-2a-hydroxy-8b-methyl-9- (1-methylethenyl) -3, 6-methano-8H-1, 5, 7-trioxacyclopenta [ij]cycloprop [a]azulene-4, 8 (3H) -dione; 3, 6-Methano-8H-1, 5, 7-trioxacyclopenta [ij]cycloprop [a]azulene-4, 8 (3H) -dione, hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-, [1aR-(1aα,2a β,3 β,6 β,6a β,8aS*,8b β,9S*)]-, compd. with [1aR-(1aα,2a β,3 β,6 β,6a β,8aS*,8b β , 9R*) ]-hexahydro-2a-hydroxy-8b-methyl-9- (1-methylethenyl) -3, 6-methano-8H-1, 5, 7-trioxacyclopenta [ij]cycloprop [a]azulene-4, 8 (3H) -dione (1:1); 3, 6-Methano-8H-1, 5, 7-trioxacyclopenta [ij]cycloprop [a]azulene-4, 8 (3H) -dione, hexahydro-2a-hy. Grades: Reagent Grade. CAS No. 124-87-8. Pack Sizes: 1g, 5g. Molecular Formula: C15H18O7·C15H16O6, Molecular Weight: 602.59. US Biological Life Sciences. |  Worldwide |
| Picrotoxinin | Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABA A receptor antagonist, which negatively modulates the action of GABA on GABA A receptors. Picrotoxinin inhibits α 1 β 2 γ 2L GABA A receptor with an IC 50 of 1.15 μM [1]. Uses: Scientific research. Group: Natural products. CAS No. 17617-45-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1494. |  |
| Picrotoxin USP | Atorvastatin Intermediate. Grades: USP. CAS No. 124-87-8. Product ID: 8-04244. Molecular formula: C30H34O13. Mole weight: 602.58. |  |
| Anisatin | Anisatin, a pure toxic substance isolated from the seeds of a Japanese plant ( Illicium anisatum ) acts as a picrotoxin-like, non-competitive GABA antagonist. Anisatin suppresses GABA-induced currents in a concentration-dependent manner with an EC 50 of ~1.10?μM [1]. Uses: Scientific research. Group: Natural products. CAS No. 5230-87-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N9506. | |
| U-93631 | U 93631 is a ligand at the picrotoxin site of GABA(A) receptors, allosterically antagonizing GABA-induced Cl- currents. U-93631 causes rapid decay of gamma-aminobutyric acid-induced chloride currents in recombinant rat gamma-aminobutyric acid type A receptors. Synonyms: 4,5-Dihydro-4,4-dimethyl-imidazo[1,5-a]quinoxaline-3-carboxylic acid 1,1-dimethylethyl ester; U93631, U-93631, U 93631. CAS No. 152273-12-6. Molecular formula: C17H21N3O2. Mole weight: 299.37. |  |
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