Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| PIK-75 | PIK-75 is a reversible DNA-PK and p110α -selective inhibitor, which inhibits DNA-PK, p110α and p110γ with IC 50 s of 2, 5.8 and 76 nM, respectively. PIK-75 inhibits p110α >200-fold more potently than p110β (IC 50 =1.3 μM) [1] [2]. PIK-75 induces apoptosis [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 372196-67-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107834. |  |
| PIK-75 | PIK-75 was developed as part of a PI 3-kinase drug discovery program. PIK75 attenuates insulin stimulation of Akt/PKB in a range of cell types at 100 nM. The compound has been reported to block growth of a range of cell lines with an IC50 value in the region of 50 nM. In vivo studies have shown that PIK-75, administered at 50 mg/kg, inhibited the growth of HeLa cell xenografts in mice models. Uses: Pi 3-kinase drug (ic50 values are 5.8, 76 nm and 1.3 μm at pi 3-kinase p110α, pi 3-kinase p110γ and pi 3-kinase p110β respectively); attenuates insulin stimulation of akt/pkb in a range of cell types at 100 nm; in vivo: studies have shown that pik-75, administered at 50 mg/kg, inhibited the growth of hela cell xenografts in mice models. Synonyms: (E)-N'-((6-bromoimidazo[1,2-a]pyridin-3-yl)methylene)-N,2-dimethyl-5-nitrobenzenesulfonohydrazide; PIK75; PIK-75; PIK 75. CAS No. 372196-67-3. Molecular formula: C16H14BrN5O4S. Mole weight: 452.30. |  |
| PIK-75 hydrochloride | PIK-75 hydrochloride is a reversible DNA-PK and p110α -selective inhibitor, which inhibits DNA-PK, p110α and p110γ with IC 50 s of 2, 5.8 and 76 nM, respectively. PIK-75 hydrochloride inhibits p110α >200-fold more potently than p110β (IC 50 =1.3 μM) [1] [2]. PIK-75 hydrochloride induces apoptosis [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 372196-77-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13281. | |
| PIK 75 hydrochloride | PIK-75 is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM. Synonyms: PIK 75 hydrochloride; PIK75 hydrochloride; PIK-75 hydrochloride. Grades: >98%. CAS No. 372196-77-5. Molecular formula: C16H14BrN5O4S.HCl. Mole weight: 488.74. | |
Our database is helping our users find suppliers everyday.
