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| Product | Description | |
|---|---|---|
| PIM447 | PIM447 (LGH447) is a potent, orally available, and selective pan- PIM kinase inhibitor, with K i values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 displays dual antimyeloma and bone-protective effects. PIM447 induces apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGH447. CAS No. 1210608-43-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-19322. |  |
| (1S,3R,5R)-PIM447 dihydrochloride | (1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM (IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3) extracted from patent US 20100056576 A1, compound example 72. Synonyms: (1S,3R,5R)-LGH447 dihydrochloride. Grade: 98%. Molecular formula: C24H25Cl2F3N4O. Mole weight: 513.38. |  |
| PIM-447 dihydrochloride | PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan- PIM kinase inhibitor, with K i values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects. PIM447 dihydrochloride induces apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LGH447 dihydrochloride. CAS No. 1820565-69-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19322B. | |
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