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Pimobendan. Group: Biochemicals. Grades: Highly Purified. CAS No. 74150-27-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences.
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Pimobendan
Pimobendan is both a calcium sensitizer and a selective inhibitor of phosphodiesterase III (PDE3) with positive inotropic and vasodilator effects. Uses: Phosphodiesterase inhibitors. Synonyms: Alprostadil;UD-CG115; UD CG115; UD-CG 115; UD-CG-115; Pimobendan; pimobendane. Trade name: Vetmedin and Acardi. Grades: >98%. CAS No. 74150-27-9. Molecular formula: C19H18N4O2. Mole weight: 334.37.
Pimobendan
Pimobendan (UD-CG115) is a selective inhibitor of PDE3 with IC 50 of 0.32 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UD-CG115. CAS No. 74150-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0204.
Pimobendan hydrochloride is a selective inhibitor of PDE3. It exhibits selective inhibition of PDE III isolated from guinea pig cardiac muscle with IC50 of 0.32 uM compared to the inhibition of PDE I and PDE II (IC50s >30 μM). It shows a beneficial effect on survival in the murine model of EMC virus-induced myocarditis. It also significantly reduces myocardial cellular infiltration, the level of intracardiac tumor necrosis factor (TNF)-α and interleukin (IL)-1β compared with the control group, which shows no effect on myocardial necrosis, heart weight and body weight. It suppresses expression of the intracardiac iNOS gene , causing reduction of intracardiac NO production. Synonyms: Vetmedin hydrochloride; Acardi hydrochloride. Grades: >98%. CAS No. 77469-98-8. Molecular formula: C19H19ClN4O2. Mole weight: 370.83.
Pimobendan Impurity A
An impurity of Pimobendan which is both a calcium sensitizer and a selective inhibitor of phosphodiesterase III (PDE3) with positive inotropic and vasodilator effects. Grades: > 95%. Molecular formula: C19H18N2O4. Mole weight: 338.37.
Pimobendan Impurity B
An impurity of Pimobendan which is a calcium sensitizer and a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilator effects. Grades: > 95%. Molecular formula: C19H20N4O3. Mole weight: 352.4.
rac Pimobendan
Pimobendan is a cardiotonic agent. The study of the cardiotonic mechanism of Pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by inhibiting phosphodiesterase III and potassium channel. The potent venodilating action of Pimobendan makes it a suitable treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction. Group: Biochemicals. Alternative Names: 4,5-Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-6-yl]-5-methyl- 3(2H)-pyridazinone; 4,5Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-3(2H)-pyridazinone; Acardi; Pimobendan;UD-CG 115; UD-CG 115BS; Vetmedin; dl-Pimobendan. Grades: Highly Purified. CAS No. 74150-27-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
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