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| Product | Description | |
|---|---|---|
| Piperazin-2-one | Piperazin-2-one. Group: Biochemicals. Alternative Names: 2-Oxopiperazine. Grades: Highly Purified. CAS No. 5625-67-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C4H8N2O. US Biological Life Sciences. |  Worldwide |
| Piperazin-2-one | Piperazin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 5625-67-2. Pack Sizes: 25 g; 100 g. Product ID: HY-20128. |  |
| 1-(2,3-Dimethyl-phenyl)-piperazin-2-one | 1-(2,3-Dimethyl-phenyl)-piperazin-2-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(2,3-DIMETHYL-PHENYL)-PIPERAZIN-2-ONE. Product Category: Heterocyclic Organic Compound. CAS No. 907972-44-5. Molecular formula: C12H16N2O. Mole weight: 204.27. Product ID: ACM907972445. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 1-(2'-Fluoro)ethyl-4-(tert-butyloxycarbonyl)piperazin-2-one | 1-(2'-Fluoro)ethyl-4-(tert-butyloxycarbonyl)piperazin-2-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(2'-FLUORO)ETHYL-4-(TERT-BUTYLOXYCARBONYL)PIPERAZIN-2-ONE. Product Category: Heterocyclic Organic Compound. CAS No. 194351-12-7. Molecular formula: C11H19FN2O3. Mole weight: 246.28. Product ID: ACM194351127. Alfa Chemistry ISO 9001:2015 Certified. | |
| 1-(3-Aminophenyl)piperazin-2-one | 1-(3-Aminophenyl)piperazin-2-one is a versatile reactant used in the preparation of pyrimidine derivatives as KDR inhibitor useful in the treatment of angiogenesis related diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 1022128-80-8. Pack Sizes: 25mg, 50mg. Molecular Formula: C10H13N3O, Molecular Weight: 191.23. US Biological Life Sciences. | Worldwide |
| 1- (3- (Trifluoromethoxy) phenyl) piperazin-2-one hydrochloride | 1- (3- (Trifluoromethoxy) phenyl) piperazin-2-one hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 215649-79-9. Pack Sizes: 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| 1- (3- (Trifluoromethoxy) phenyl) piperazin-2-one hydrochloride ≥96% (HPLC) | 1- (3- (Trifluoromethoxy) phenyl) piperazin-2-one hydrochloride ≥96% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| 1-(4-Methoxybenzyl)piperazin-2-one | 1-(4-Methoxybenzyl)piperazin-2-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(4-METHOXYBENZYL)PIPERAZIN-2-ONE. Product Category: Heterocyclic Organic Compound. CAS No. 893747-38-1. Molecular formula: C12H16N2O2. Mole weight: 220.27. Product ID: ACM893747381. Alfa Chemistry ISO 9001:2015 Certified. | |
| 1-(4-Methoxy-phenyl)-piperazin-2-one | 1-(4-Methoxy-phenyl)-piperazin-2-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(4-METHOXY-PHENYL)-PIPERAZIN-2-ONE. Product Category: Heterocyclic Organic Compound. CAS No. 215649-82-4. Molecular formula: C11H14N2O2. Mole weight: 206.24. Product ID: ACM215649824. Alfa Chemistry ISO 9001:2015 Certified. Categories: 1-(4-methoxyphenyl)piperazin-2-one. | |
| 1-(4-Methylphenyl)piperazin-2-one | 1-(4-Methylphenyl)piperazin-2-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-P-TOLYL-PIPERAZIN-2-ONE;1-(4-METHYLPHENYL)PIPERAZIN-2-ONE;OTAVA-BB 1310643. Product Category: Heterocyclic Organic Compound. CAS No. 893748-24-8. Molecular formula: C11H14N2O. Mole weight: 190.24. Product ID: ACM893748248. Alfa Chemistry ISO 9001:2015 Certified. | |
| 1- (4- (Trifluoromethoxy) phenyl) piperazin-2-one hydrochloride | 1- (4- (Trifluoromethoxy) phenyl) piperazin-2-one hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 267659-71-2. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| 1- (4- (Trifluoromethoxy) phenyl) piperazin-2-one hydrochloride ≥96% | 1- (4- (Trifluoromethoxy) phenyl) piperazin-2-one hydrochloride ≥96%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| 3-(4-Fluoro-phenyl)-piperazin-2-one | 3-(4-Fluoro-phenyl)-piperazin-2-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(4-FLUORO-PHENYL)-PIPERAZIN-2-ONE. Product Category: Heterocyclic Organic Compound. CAS No. 85606-96-8. Molecular formula: C10H11FN2O. Mole weight: 194.21. Product ID: ACM85606968. Alfa Chemistry ISO 9001:2015 Certified. Categories: 3-(4-FLUOROPHENYL)PIPERAZIN-2-ONE. | |
| Nutlin-3 ((±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one) | Cell-permeable. Nutlin-3 is a Mdm2 (mouse double minute 2) antagonist (IC50=90nM for Nutlin-3a and 13.6uM for Nutlin-3b), p53 pathway activator, and apoptosis inducer. Group: Biochemicals. Grades: Highly Purified. CAS No. 548472-68-0. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| 1-(2-Fluorophenyl)-2-piperazinone | 1-(2-Fluorophenyl)-2-piperazinone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(2-FLUORO-PHENYL)-PIPERAZIN-2-ONE;1-(2-Fluorophenyl)-2-piperazinone. Product Category: Heterocyclic Organic Compound. CAS No. 907972-55-8. Molecular formula: C10H11FN2O. Mole weight: 194.21. Density: 1.225. Product ID: ACM907972558. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-Piperazinone | 2-Piperazinone. Group: Biochemicals. Alternative Names: Tetrahydro-2(1H)-pyrazinone; 2-Ketopiperazine; 2-Oxopiperazine; 3-Oxopiperazine; Oxopiperazine; Piperazin-2-one; Piperazine-2-one; NSC 27441. Grades: Highly Purified. CAS No. 5625-67-2. Pack Sizes: 2g. US Biological Life Sciences. | Worldwide |
| 4-[(2-Aminoethyl)sulfonyl]-piperazinone | 4-[(2-Aminoethyl)sulfonyl]-piperazinone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-[(2-AMINOETHYL)SULFONYL]-PIPERAZINONE;4-[(2-AMINOETHYL)SULFONYL]-PIPERAZIN-2-ONE HYDROCHLORIDE. Product Category: Heterocyclic Organic Compound. CAS No. 800388-09-4. Molecular formula: C6H13N3O3S. Mole weight: 207.25. Product ID: ACM800388094. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4-Boc-2-oxopiperazine | 4-Boc-2-oxopiperazine. Group: Biochemicals. Alternative Names: 1,1-Dimethylethyl 3-oxo-1-piperazinecarboxylate; 1- (tert-Butoxycarbonyl) piperazin-3-one; 1-Boc-3-oxo-piperazine; 1-tert-Butoxycarbonyl-3-oxopiperazine; 2-Oxo-4- (tert-butoxycarbonyl) piperazine; 3-Oxo-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester; 3-Oxopiperazine-1-carboxylic Acid tert-Butyl Ester; 3-Oxopiperazine-1-carboxylic Acid tert-Butyl Ester; 4-(tert-Butyloxycarbonyl)-2-piperazinone; 4-tert-Butoxycarbonyl piperazin-2-one; tert-Butyl 3-oxo-1-piperazinecarboxylate. Grades: Highly Purified. CAS No. 76003-29-7. Pack Sizes: 1g. Molecular Formula: C9H16N2O3, Molecular Weight: 200.23. US Biological Life Sciences. | Worldwide |
| Evogliptin | This active molecular is a selective dipeptidyl peptidase 4 (DPP4) inhibitor under the development of Dong-A. Evogliptin improves insulin resistance and delays the onset of diabetes. Evogliptin monotherapy improved HbA1c, fasting plasma glucose level, OGTT results and β-cell function. In Sep 1st 2016, preclinical trials in Type-2 diabetes mellitus (Combination therapy) in Russia was on-going. In Sep 12th 2016, Phase-I clinical trials in non-alcoholic steatohepatitis (Combination therapy) in USA was on-going. Uses: Type-2 diabetes mellitus. Synonyms: (3R)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-[(2-methylpropan-2-yl)oxymethyl]piperazin-2-one;CHEMBL1779710; UNII-09118300L7; DA-1229; DA 1229; DA1229; 1222102-29-5; Evogliptin [INN];1246960-27-9 (HCl). Grades: 98%. CAS No. 1222102-29-5. Molecular formula: C19H26F3N3O3. Mole weight: 401.43. |  |
| Nutlin-3 | Nutlin-3 is an MDM2 antagonist, inhibiting p53-Mdm2 interaction (IC50=0.09 μM) via affecting p53 binding pocket of MDM2. It has been studied in anticancer reseaches. Synonyms: (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one; 4-[4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one. Grades: >98%. CAS No. 548472-68-0. Molecular formula: C30H30Cl2N4O4. Mole weight: 581.49. | |
| Nutlin-3b | Nutlin-3b, the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM. Synonyms: Nutlin-3; nutlin 3; Nutlin 3b; FJA1772CVW; (+)-Nutlin-3; CHEMBL2152332; CHEBI:46742; 4-[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one; 2-Piperazinone, 4-(((4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-(4-methoxy-2-(1-methylethoxy)phenyl)-1H-imidazol-1-yl)carbonyl)-; 4-((4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)piperazin-2-one; 4-[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl]piperazin-2-one; 4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone; cis-4-{[4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydroimidazol-1-yl]carbonyl}piperazin-2-one. Grades: >98%. CAS No. 675576-97-3. Molecular formula: C30H30Cl2N4O4. Mole weight: 581.49. | |
| Piperazinone,1-(2-thiazolyl)-(9ci) | Piperazinone,1-(2-thiazolyl)-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-(1,3-THIAZOL-2-YL)PIPERAZIN-2-ONE, 374795-53-6, SureCN1583412, CTK4H8247, 2-Piperazinone,1-(2-thiazolyl)-, 1-(2-THIAZOLYL)-PIPERAZINONE, AKOS006286545, AB37126, AG-F-31739, Piperazinone,1-(2-thiazolyl)- (9CI), 1-THIAZOL-2-YL-PIPERAZIN-2-ONE, PIPERAZINONE, 1-(2-THIAZOLYL)-. Product Category: Heterocyclic Organic Compound. CAS No. 374795-53-6. Molecular formula: C7H9N3OS. Mole weight: 183.23086. Purity: 0.96. IUPACName: 1-(1,3-thiazol-2-yl)piperazin-2-one. Product ID: ACM374795536. Alfa Chemistry ISO 9001:2015 Certified. | |
| Piperazinone,3-[2-(methylthio)ethyl]-(9ci) | Piperazinone,3-[2-(methylthio)ethyl]-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: AG-H-15116, 78551-63-0, PIPERAZINONE, 3-[2-(METHYLTHIO)ETHYL]-, 3-[2-(METHYLSULFANYL)ETHYL]PIPERAZIN-2-ONE, AGN-PC-00MWCZ, SureCN10842286, CTK5E5900, AKOS011636378, AB37175, 2-Piperazinone,3-[2-(methylthio)ethyl]-, 3-[2-(METHYLTHIO)ETHYL]-PIPERAZINONE, Piperazinone,3-[2-(methylthio)ethyl]- (9CI), 3-(2-(METHYLTHIO)ETHYL)PIPERAZIN-2-ONE, 3-(2-METHYLSULFANYL-ETHYL)-PIPERAZIN-2-ONE. Product Category: Heterocyclic Organic Compound. CAS No. 78551-63-0. Molecular formula: C7H14N2OS. Mole weight: 174.26386. Purity: 0.96. IUPACName: 3-(2-methylsulfanylethyl)piperazin-2-one. Canonical SMILES: CSCCC1C(=O)NCCN1. Product ID: ACM78551630. Alfa Chemistry ISO 9001:2015 Certified. | |
| Tenilsetam | Tenilsetam is an endonuclease modulator, also a nootropic agent and advanced glycation end product (AGE) inhibitor with the potential to treat Alzheimer's disease (AD). Preclinical studies indicated that tenilsetam may have an inhibitory effect on diabetic retinopathy, without amelioration of pericyte loss. Uses: Potential treatment of alzheimer's disease. Synonyms: 3-(thiophen-2-yl)piperazin-2-one; 3-thiophen-2-ylpiperazin-2-one; 3-(2-thienyl)piperazin-2-one. Grades: 99%. CAS No. 86696-86-8. Molecular formula: C8H10N2OS. Mole weight: 182.24. | |
| Triclofenol Piperazine | Triclofenol piperazine is used for the treatment of patients infected with parasite such as hookworms. Uses: Triclofenol piperazine is used for the treatment of patients infected with parasite such as hookworms. Synonyms: CI-416; CI416; CI 416; Triclofenol piperazate; Triclofenol piperazina; Piperazin-2-one compound with 2,4,5-trichlorophenol. Grades: 98%. CAS No. 5714-82-9. Molecular formula: C16H16Cl6N2O2. Mole weight: 481.03. | |
| MDM2 Antagonist IV, Nutlin-3a ((-)-4-(4,5-bis-(4-Chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydroimidazole-1-carbonyl)piperazine-2-one) | A cell-permeable and highly potent active enantiomer of Nutlin-3 that binds to the p53-binding pocket and blocks the interaction of p53 and MDM2 (IC50=90nM). Exhibits over 150-fold greater affinity for MDM2 than its less active enantiomer, Nutlin-3b. Induces p53 mediated apoptosis by both transcription-dependent and independent mechanisms. Shown to greatly potentiate the cytotoxic effects of chemotherapeutic agents and reduce tumor burden in vivo. Also shown to overcome ATM-mediated resistance to fludarabine in chronic lymphocyte leukemia. Cells treated with Nutlin-3a permanently lose their ability to proliferate and enter into a pattern of permanent senescence. Mouse embryonic fibroblasts with p53+/+ MEFs show significantly reduced reprogramming capabilities following Nutlin-3a treatment. Group: Biochemicals. Grades: Highly Purified. CAS No. 675576-98-4. Pack Sizes: 5mg. Molecular Formula: C??H??Cl?N?O?. US Biological Life Sciences. | Worldwide |
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