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| Product | Description | |
|---|---|---|
| Pirinixic acid | Pirinixic acid (Wy-14643) is a potent agonist of PPARα , with EC 50 s of 0.63 μM, 32 μM for murine PPARα and PPARγ, and 5.0 μM, 60 μM, 35 μM for human PPARα , PPARγ and PPARδ, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Wy-14643. CAS No. 50892-23-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-16995. |  |
| Pirinixic Acid | WY 14643 (Pirinixic Acid) is a potent peroxisome proliferator and activator of PPARα with EC50 of 1.5 μM. Uses: Carcinogens. Synonyms: WY-14643; WY 14643; WY14643; Pirinixic Acid. Grades: >98%. CAS No. 50892-23-4. Molecular formula: C14H14ClN3O2S. Mole weight: 323.8. |  |
| Pirinixic acid aminothiazole | Pirinixic acid aminothiazole is a dual inhibitor of 5-lipoxygenase (5-LO) and microsomal prostaglandin E2 synthase 1 (mPGES-1) with IC50 values of 0.4 and 0.2 μM, respectively. It also weakly inhibits COX-1 and -2. Synonyms: 2-[4-Chloro-6-[4-(2-naphthyl)-2-thiazolylamino]-2-pyrimidinylthio]octanoic acid. Grades: ≥98%. CAS No. 1492060-44-2. Molecular formula: C25H25ClN4O2S2. Mole weight: 513.1. | |
| WY-14643 ( [ [4-Chloro-6- [ (2, 3-dimethylphenyl) -amino] -2-pyrimidinyl] thio] acetic Acid, Pirinixic Acid) | Cell-permeable. A selective PPARa agonist (EC50 values are 0.63, 32 and > 100uM at PPARa, PPARg and PPARd respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 50892-23-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| 2-Amino-4-(1-naphthyl)thiazole | 2-Amino-4-(1-naphthyl)thiazole is a reagent used in the synthesis of 2-substituted ethenesulfonic acid ester derivatives as PTP1B inhibitors. Also used as a reagent in the preparation of pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors for the treatment of inflammation and various cancers. Group: Biochemicals. Grades: Highly Purified. CAS No. 56503-96-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C13H10N2S, Molecular Weight: 226.3. US Biological Life Sciences. | Worldwide |
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