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| Product | Description | |
|---|---|---|
| PK 11195 | Cell-permeable. A Selective peripheral benzodiazepine antagonist. Enhances apoptosis and induces mitochondria cytochrome c release. Inhibits insulin secretion induced by glucose. Also displays anticancer activity. Group: Biochemicals. Alternative Names: 1- (2-Chloro phenyl ) -N- methyl -N- (1- methyl propyl ) -3-isoquinolinecarboxamid e . Grades: Highly Purified. CAS No. 85532-75-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| PK 11195 | PK 11195 has high affinity for the peripheral benzodiazepine receptor (PBR, TSPO) without binding to other known neurotransmitter receptors. It can also inhibit the human constitutive androstane receptor (hCAR). In Mar 2006, Preclinical for Cancer in United Kingdom was discontinued. Uses: Anticancer. Synonyms: PK11195; PK-11195; PK 11195. 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide; N-Methyl-N-(1-methylpropyl)-1-(2-chlorophenyl)isoquinoline-3-carboxamide; RP 52028; RP52028; RP-52028. Grades: 98%. CAS No. 85532-75-8. Molecular formula: C21H21ClN2O. Mole weight: 352.86. |  |
| PK 11195 | PK 11195 (RP 52028) is a ligand of translocator protein (TSPO) , which targets Leishmania chemotherapy, with IC 50 s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis , L. major and L. braziliensis , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP 52028. CAS No. 85532-75-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19567. |  |
| PK 11195 (1- (2-Chloro phenyl ) -N- methyl -N- (1- methyl propyl ) -3-isoquinolinecarboxamid e ) | Selective peripheral benzodiazepine antagonist. Apoptosis enhancer. Glucose-induced insulin secretion inhibitor. Induces mitochondria cytochrome c release. Anticancer compound. Antiproliferative. Pharmacological tool in autophagy. Group: Biochemicals. Grades: Highly Purified. CAS No. 85532-75-8. Pack Sizes: 10mg. Molecular Formula: C21H21ClN2O, Molecular Weight: 352.9. US Biological Life Sciences. | Worldwide |
| N-Desmethyl-PK 11195 | N-Desmethyl-PK 11195 is a precursor to [N-methyl-11C]PK 11195 for PET studies and a radioligand precursor to the peripheral benzodiazepine antagonist PK 11195. Synonyms: N-sec-Butyl-1-(2-chlorophenyl)isoquinoline-3-carboxamide; (R)-N-Desmethyl PK11195; 1-(2-chlorophenyl)-N-(1-methylpropyl)-3-isoquinoline carboxamide; ACMC-1C1J3. Grades: 99%. CAS No. 124236-61-9. Molecular formula: C20H19ClN2O. Mole weight: 338.83. | |
| (R)-(-)-N-Desmethyl-PK 11195 | (R)-(-)-N-Desmethyl-PK 11195 is a precursor to (R)-[N-methyl-11C]PK 11195 for PET studies and a radioligand precursor to the peripheral benzodiazepine antagonist (R)-[N-methyl-11C]PK 11195. Synonyms: (R)-N-Desmethyl PK11195; (R)-N-(1-methylpropyl)-1-(2-chlorophenyl)isoquinoline-3-carboxamide. Grades: 99%. CAS No. 157809-85-3. Molecular formula: C20H19ClN2O. Mole weight: 338.83. | |
| (R)-(-)-PK 11195 | (R)-(-)-PK 11195 is the (R)-enantiomer of PK 11195, which is a peripheral benzodiazepine antagonist with high affinity for PBR in all species. It is used as a drug reference standard of [11C](R)-PK 11195 in PET studies. Synonyms: (R)-(-)-PK 11195; (R)-(-)-PK11195; (R)-(-)-PK-11195. Grades: 99%. CAS No. 205934-46-9. Molecular formula: C21H21ClN2O. Mole weight: 352.86. | |
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