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| Product | Description | |
|---|---|---|
| PKI-179 | PKI-179 is a second generation, small-molecule mimetic of ATP that targets the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. PKI-179 selectively inhibits mTOR and phosphoinositide-3-kinase (PI3K) alpha. By inhibiting the PI3K/mTOR signaling pathway, this agent may inhibit tumor cell proliferation and survival. Synonyms: PKI-179; PKI 179; PKI179. Grades: ≥98%. CAS No. 1197160-28-3. Molecular formula: C25H28N8O3. Mole weight: 488.55. |  |
| PKI-179 hydrochloride | PKI-179 is an orally bioavailable dual inhibitor of PI3K and mammalian target of rapamycin (mTOR), displaying potential antineoplastic activity. Synonyms: N-[4-[4-(4-morpholinyl)-6-(3-oxa-8-azabicyclo[3.2.1]oct-8-yl)-1,3,5-triazin-2-yl]phenyl]-N'-4-pyridinyl-urea monohydrochloride. Grades: ≥98%. CAS No. 1463510-35-1. Molecular formula: C25H28N8O3·HCl. Mole weight: 525. | |
| PI 3-K/mTOR Inhibitor III, PKI-179 - CAS 1197160-28-3 | The PI 3-K/mTOR Inhibitor III, PKI-179, also referenced under CAS 1197160-28-3, controls the biological activity of PI 3-K/mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. |  |
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