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| Product | Description | |
|---|---|---|
| Pluripotin | Pluripotin is a dual inhibitor of ERK1 and RasGAP with K D s of 98 nM and 212 nM, respectively. Pluripotin also inhibits RSK1 , RSK2 , RSK3 , and RSK4 with IC 50 s of 0.5, 2.5, 3.3, and 10.0 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC1. CAS No. 839707-37-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10579. |  |
| Pluripotin | Pluripotin is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. Pluripotin has been shown to maintain embryonic stem cell (ESC) self-renewal. When combined with leukemia inhibitory factor, Pluripotin greatly promotes derivation of embryonic stem cell lines from refractory strains. Group: Biochemicals. Alternative Names: N-[3-[7-[ (1, 3-Dimethyl-1H-pyrazol-5-yl) amino]-1, 4-dihydro-1-methyl-2-oxopyrimido[4, 5-d]pyrimidin-3 (2H) -yl]-4-methylphenyl]-3- (trifluoromethyl) benzamide; N-[3-[7- (2, 5-Dimethyl-2H-pyrazol-3-ylamino) -1-methyl-2-oxo-1, 4-dihydro-2H-pyrimido[4, 5-d]pyrimidin-3-yl]-4-methylphenyl]-3-trifluoromethyl-benzamide; SC 1; Stemolecule SC 1. Grades: Highly Purified. CAS No. 839707-37-8. Pack Sizes: 2.5mg. US Biological Life Sciences. |  Worldwide |
| Pluripotin | SC1 (Pluripotin) was identified in a cell-based chemical library screen for small molecules that regulate mouse embryonic stem (ES) cell self-renewal. SC1 is sufficient to sustain long-term self-renewal of mouse ES cells in an undifferentiated state in the absence of LIF, feeder cells, or serum. SC1 acts through dual inhibition of extracellular signal-regulated kinase 1 (ERK1) and Ras GTPase-activating protein (Ras-GAP). Mouse ES cells maintained in the presence of SC1 retain their ability to differentiate into cells representing all three germ layers in vitro, form chimeric mouse, and contribute to germ line in vivo. Uses: Self-renewal. Synonyms: SC-1; SC 1; SC1; Pluripotin. Grades: 0.98. CAS No. 839707-37-8. Molecular formula: C27H25F3N8O2. Mole weight: 550.54. |  |
| Pluripotin (SC-1, SC1) | Pluripotin (SC-1, SC1). Group: Biochemicals. Alternative Names: N- (3- (7- (1, 3-dimethyl-1H-pyrazol-5-ylamino) -1-methyl-2-oxo-1, 2-dihydropyrimido[4, 5-d]pyrimidin-3 (4H) -yl) -4-methylphenyl) -3- (trifluoromethyl) benzamide. Grades: Highly Purified. CAS No. 839707-37-8. Pack Sizes: 10mg. Molecular Formula: C27H25F3N8O2 , Molecular Weight: 550.5. US Biological Life Sciences. | Worldwide |
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