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PMX 205 PMX 205. Group: Biochemicals. Grades: Purified. CAS No. 514814-49-4. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 5
Worldwide
PMX 205 PMX 205 is a potent C5a receptor peptide antagonist (IC50 = 31 nM). It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma. PMX 205 reduces fibrillar amyloid deposits, decreases hyperphosphorylated tau levels and rescues cognitive function in a mouse model of Alzheimer's Disease. Synonyms: PMX-205; Hydrocinnamate. Grades: >98%. CAS No. 514814-49-4. Molecular formula: C45H62N10O6. Mole weight: 839.05. BOC Sciences 8
PMX 205 acetate PMX 205 acetate is a potent complement C5a receptor antagonist (IC50 = 31 nM). It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma. PMX 205 reduces fibrillar amyloid deposits, decreases hyperphosphorylated tau levels and rescues cognitive function in a mouse model of Alzheimer's Disease. Synonyms: hydrocinnamoyl-Orn(1)-Pro-D-Cha-Trp-Arg-(1).CH3CO2H; L-Arginine, N2-(1-oxo-3-phenylpropyl)-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-, (5?1)-lactam acetate; PMX205 acetate; PMX-205 acetate; Hydrocinnamate-(Orn-Pro-DCHA-Trp-Arg) acetate. Grades: ≥95%. Molecular formula: C47H66N10O8. Mole weight: 899.09. BOC Sciences 6

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