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PNU 282987 PNU 282987. Group: Biochemicals. Grades: Purified. CAS No. 123464-89-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
PNU 282987 PNU 282987 is a potent and selective agonist of α7-containing neuronal nicotinic acetylcholine receptors (nAChRs). It exhibits nootropic effects, suggesting its potential use in the treatment of schizophrenia. Synonyms: N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-4-chlorobenzamide. Grades: ≥98%. CAS No. 711085-63-1. Molecular formula: C14H17ClN2O. Mole weight: 264.8. BOC Sciences 10
PNU 282987 (PNU-282987, N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide Hydrochloride, alpha7 nAChR Agonist, PNU 282987, alpha 7 Nicotinic Acetylcholine Receptor Agonist, PNU 282987, PNU282987) A potent agonist highly selective for alpha7 nAChRs (Ki = 26nM). Used in investigating the roles of alpha7 nAChRs in sensory gating, learning and memory, cognitive functions, and treatment of Schizophrenia. Group: Biochemicals. Grades: Highly Purified. CAS No. 123464-89-1. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
PNU-282987 hydrochloride PNU-282987 is a highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). Found to be inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM). Synonyms: PNU-282987; PNU 282987; PNU282987; Benzamide, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chloro-. Grades: >98%. CAS No. 123464-89-1. Molecular formula: C14H18Cl2N2O. Mole weight: 301.21. BOC Sciences 8

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