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| Product | Description | |
|---|---|---|
| Poloxin | Poloxin is a non-ATP competitive Polo-like Kinase 1 (PLK1) inhibitor that targets the polo-box domain, with an IC50 of appr 4.8 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 321688-88-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12134. |  |
| Polo-like Kinase Inhibitor V, Poloxin (2-isopropyl-5-methyl-4- (2-methylbenzoyloxyimino) cyclohexa-2, 5-dienone) | A thymoquinone derivative, non-ATP competitive Polo-like Kinase 1 (Plk1) inhibitor specifically targeting the polo-box domain (PBD) of Plk1 (IC50)=4.8uM. Reduces both chromosome and kinetochoral localization of Plk1, induces chromosome congression defects , mitotic arrest in prometaphase, and apoptosis in HeLa cells at 25uM. Exhibits anti-proliferative effects in a range of cancer cell lines, and in a mouse Xenograft model involving HeLa and MDA-MB-231 cells at 40mg/kg. Group: Biochemicals. Grades: Highly Purified. CAS No. 321688-88-4. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Polo-like Kinase Inhibitor V, Poloxin - CAS 321688-88-4 | The Polo-like Kinase Inhibitor V, Poloxin, also referenced under CAS 321688-88-4, controls the biological activity of Polo-like Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. |  |
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