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Custom. Synonyms: PLGA; Poly(DL-lactic-co-glycolic acid). CAS No. 26780-50-7. Product ID: PE-0506. Category: Carrier Excipients. Product Keywords: Pharmaceutical Excipients; Other Materials; Poly(lactide-co-glycolide); Carrier Excipients; Carrier Excipients; /; 26780-50-7; 26780-50-7. UNII: WE369X5600(50:50); 58X445TH30(75:25). Chemical Name: Poly(lactide-co-glycolide). Grade: Pharmceutical Excipients. Administration route: Endosinusial; Inyrravitreal; Subcutaneous; Intramuscular. Dosage Form: Implant; Injection; soultion, powder, for suspension. Stability and Storage Conditions: Sealed, refrigerated or frozen (-20-8°C), bring product close to room temperature before opening to minimize degradation due to moisture condensation. Commonly used amount and the maximum amount: Lactide-co-glycolide (75:25) intramuscular injection maximum dosage of 81.2mg. Source and Preparation: Traditional PLGA preparation methods include ring-opening polymerization and direct polymerization. The ring-opening polymerization method is currently the most commonly used and mature PLGA synthesis method. It is divided into ring-opening random copolymerization and ring-opening homopolymerization. The former synthesizes random copolymers, although different compositions can be synthesized by controlling different feeding ratios. PLGA, but the degree of randomness and compositional reproducibility of the resulting product is difficul
PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs. Uses: Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs. Group: Biodegradable polymerspoly(ethylene glycol) and poly(ethylene oxide). Alternative Names: PLGA-PEG-PLGA. Pack Sizes: 1 g in glass bottle. Molecular formula: PEG average Mn 1,000 PLGA average Mn 2,200 average Mn (1100-1000-1100).
Poly(lactide-co-glycolide)-Rhodamine B
Poly(lactide-co-glycolide)-Rhodamine B. Synonyms: PLGA, PLGA-Rhodamine B. Product ID: MSMN-075. Category: Raw Materials.
Contains ≤500 ppm impurities by GC, including trace monomer and residual organics. Uses: Biocompatible block copolymer. can be used in the formation of nanoparticles for drug delivery. potential use in the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anesthetic agents. Group: Biodegradable polymerspoly(ethylene glycol) and poly(ethylene oxide). Alternative Names: PEG-PLGA, mPEG-b-PLGA. Molecular formula: PEG average Mn 5,000 PLGA Mn 5,000. Mole weight: H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nCH3.
Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part. Synonyms: Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide). Product ID: MSMN-036. Category: Raw Materials.
Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part. Synonyms: Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide). Product ID: MSMN-034. Category: Raw Materials.
mPEG-b-PLGA (PEG Mn 5,000, PLGA Mn 10,000)
Contains ≤500 ppm impurities by GC, including trace monomer and residual organics. Synonyms: Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide). Product ID: MSMN-042. Category: Raw Materials.
mPEG-b-PLGA (PEG Mn 5,000, PLGA Mn 15,000)
Contains ≤500 ppm impurities by GC, including trace monomer and residual organics. Synonyms: Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide). Product ID: MSMN-041. Category: Raw Materials.
mPEG-b-PLGA (PEG Mn 5,000, PLGA Mn 20,000)
Contains ≤500 ppm impurities by GC, including trace monomer and residual organics. Synonyms: Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide). Product ID: MSMN-035. Category: Raw Materials.
mPEG-b-PLGA (PEG Mn 5,000, PLGA Mn 5,000)
Contains ≤500 ppm impurities by GC, including trace monomer and residual organics. Synonyms: Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide). Product ID: MSMN-038. Category: Raw Materials.
mPEG-b-PLGA (PEG Mn 5,000, PLGA Mn 7,000)
Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part. Synonyms: Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide). Product ID: MSMN-037. Category: Raw Materials.
Fluorescein labeled poly(L-lactide-co-glycolide) (PLGA-FITC, PLGA-Fluorescein) can be used to prepare fluorescent nanoparticles. Synonyms: Poly(lactide-co-glycolide)-fluorescein. Product ID: MSMN-073. Category: Raw Materials.
PLGA-PEG-PLGA (Mn (1000-1000-1000))
PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs. Synonyms: Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide). Product ID: MSMN-069. Category: Raw Materials.
PLGA-PEG-PLGA (Mn (1100-1000-1100))
PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs. Synonyms: Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide). Product ID: MSMN-068. Category: Raw Materials.
Since PLLA itself is a hard and brittle material, modifications to enhance the softness and elasticity of PLLA could broaden the applicability of biodegradable polymers in biomedical applications. The introduction of soft segments such as poly(?-caprolactone) (PCL) can effectively make PLLA more soft and elastic. Uses: Poly(l-lactide-co-caprolactone-co-glycolide) (plga-pcl) is a biodegradable block copolymer that may be used as nanoparticle-based drug delivery systems. electrospun nanofiber blend of plga-pcl, phosphorylcholine groups and an antiproliferative (rapamycin)may be used as vascular grafts and prostheses. Group: 3d printing materials biodegradable polymers. Alternative Names: Poly-L -lactide-co-glycolide-co-ε-caprolactone, ε-Caprolactone-glycolide-L -lactide copolymer. CAS No. 134490-19-0. Pack Sizes: 1, 5 g in glass bottle. Molecular formula: average Mn ~50,000 by GPC.