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Product
Porfiromycin Antibiotic substance isolated from a Streptomyces ardus fermentation broth. Antibacterial; antineoplastic. Group: Biochemicals. Alternative Names: (1aS, 8S, 8aR, 8bS) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-1, 5-dimethylazirino[2', 3': 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; ENT 50825; Methyl Mitomycin C; Methylmitomycin; N-Methylmitomycin C; NCI 56410; NSC 56410; Porfiromycine; Regamycin; U 14743. Grades: Highly Purified. CAS No. 801-52-5. Pack Sizes: 1mg, 2mg. US Biological Life Sciences. USBiological 3
Worldwide
Porfiromycin Porfiromycin is a quinone antibiotic produced by Str. ardus NRRL 2817. It has anti-Gram-positive and negative bacteria activity. It can inhibit sarcoma-180, Ehrlich ascites carcinoma, L-1210, H leukemia (solid type). The dose of inhibiting KB cell protein synthesis is 0.5 μg/mL. It is a bioreductive DNA alkylating agent that preferentially kills hypoxic tumor cells relative to other aerobic counterparts. Synonyms: N-Methylmitomycin C; NSC-56410; U-14743; Methylmitomycin; Methyl mitomycin C; Regamycin; Mitiromycin D; Porphyromycin; (1aS, 8S, 8aR, 8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-1, 5-dimethylazirino[2', 3':3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: >98%. CAS No. 801-52-5. Molecular formula: C16H20N4O5. Mole weight: 348.35. BOC Sciences 6

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