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| Product | Description | |
|---|---|---|
| Pozanicline | Pozanicline, a pyridine derivative, has been found to be a nicotinic receptor modulator that was once studied in Alzheimer's disease as a neuroprotective agent. Synonyms: Pozanicline; ABT-089; ABT 089; ABT089; A-87089; A-87089.0; Pozanicline; UNII-CL2002R563; CHEMBL127071; Pozanicline (USAN); 2-methyl-3-[[(2S)-pyrrolidin-2-yl]methoxy]pyridine. Grades: 98%. CAS No. 161417-03-4. Molecular formula: C11H16N2O. Mole weight: 192.26. |  |
| Pozanicline dihydrochloride | Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable nicotinic acetylcholine receptor ( nAChR ) agonist with a K i of 16.7 nM for binding to [ 3 H]cytisine sites [1]. Pozanicline is an α4β2 -selective nAChR agonist, which binds to rat brain α4β2 nAChR with a K i of 17 nM while binding to α7 nAChR is insignificant [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-089 dihydrochloride. CAS No. 161416-61-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-110160. |  |
| ABT 089 dihydrochloride | ABT 089 dihydrochloride is a selective α4β2 nicotinic acetylcholine receptor partial agonist (Ki = 16 nM) with >1000-fold and >10,000-fold selectivity for α4β2 over α1β1γ1 and α7 receptors, respectively. ABT 089 dihydrochloride is used as a nootropic and neuroprotective agent. Uses: Nootropic and neuroprotective agent. Synonyms: ABT 089 dihydrochloride; ABT089 dihydrochloride; ABT-089 dihydrochloride; 2-Methyl-3-[(2S)-pyrrolidinylmethoxy]pyridine dihydrochloride; Pozanicline hydrochloride. Grades: ≥98% by HPLC. CAS No. 161416-61-1. Molecular formula: C11H16N2O.2HCl. Mole weight: 265.18. | |
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