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| Product | Description | |
|---|---|---|
| PP242 | PP242 is a novel potent and selective mTOR inhibitor with an IC50 of 8 nM. PP242 also shows residual (micromolar) activity against panel of tyrosine kinases. But PP242 was much less active against other PI3K family members with IC50 of 2, 2.2, 0.1, 1.3 and 0.41 μM for p110α, p110β, p110δ, p110γ and DNA-PK, respectively. Synonyms: PP 242; PP-242; Torkinib. CAS No. 1092351-67-1. Molecular formula: C16H16N6O. Mole weight: 308.345. |  |
| PP242 (2-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol) | A potent and selective in vitro mTOR inhibitor that targets the ATP domain of mTOR (IC?? = 8 nM). Inhibits other PI 3-Kinases only at much higher concentrations. Recently it has been shown that PP242 is a more effective mTORC1 inhibitor than Rapamycin. Group: Biochemicals. Grades: Highly Purified. CAS No. 1092351-67-1. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| PP242 hydrate | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. |  |
| mTOR Inhibitor III, PP242 | The mTOR Inhibitor III, PP242 controls the biological activity of mTOR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. | |
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