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| Product | Description | |
|---|---|---|
| PPTN hydrochloride | PPTN, a 4,7-disubstituted 2-naphthoic acid derivative, is a high affinity and selective P2Y14 antagonist (KB = 434 pM) with >10,000-fold selectivity for P2Y14 over other P2Y receptors. PPTN blocks UDP-glucose-promoted chemotaxis of human neutrophils and does so across a concentration range consistent with its KB determined in the P2Y14-R-expressing cell line. Synonyms: 4-[4-(4-Piperidinyl)phenyl]-7-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxylic acid hydrochloride. Grades: ≥98% by HPLC. CAS No. 1992047-65-0. Molecular formula: C29H24F3NO2.HCl. Mole weight: 511.96. |  |
| PPTN hydrochloride | PPTN hydrochloride is a potent, high-affinity, competitive and highly selective P2Y14 receptor antagonist with a K B value of 434 pM. PPTN hydrochloride exhibits no agonist or antagonist effect at the P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors. Anti-inflammatory and anti-immune activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1992047-65-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110322. |  |
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