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| Product | Description | |
|---|---|---|
| prepilin peptidase | Many species of bacteria carry pili on their cell surfaces. These are virulence determinants in pathogenic strains, and are assembled biosynthetically from type IV prepilin subunits. Before assembly, the prepilin molecules require proteolytic processing, which is done by the prepilin peptidase. Prepilin peptidase and its homologues play a central role not only in type IV pilus biogenesis but also in transport of macromolecules across cell membranes. Although both peptide-bond hydrolysis and N-methylation are catalysed by the same molecule, the methylation can be inhibited without affecting peptidase activity, and it is believed that the enzyme has two separate catalytic sites. Type example of peptidase family A24. Group: Enzymes. Enzyme Commission Number: EC 3.4.23.43. CAS No. 202833-59-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4280; prepilin peptidase; EC 3.4.23.43; 202833-59-8. Cat No: EXWM-4280. |  |
| preflagellin peptidase | An aspartic peptidase from Archaea but not bacteria. In peptidase family A24 (type IV prepilin peptidase family). Group: Enzymes. Synonyms: FlaK. Enzyme Commission Number: EC 3.4.23.52. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4290; preflagellin peptidase; EC 3.4.23.52; FlaK. Cat No: EXWM-4290. | |
| signal peptidase I | The enzyme is found in bacterial membranes and in chloroplast thylakoid membranes. Unaffected by inhibitors of most serine peptidases, but site-directed mutagenesis implicates a Ser/Lys catalytic dyad in activity. Hydrolyses a single bond -Ala?Ala- in M13 phage procoat protein, producing free signal peptide and coat protein. Formerly included in EC 3.4.99.36. Eukaryote signal peptidases that may have somewhat different specificity are known from the endoplasmic reticulum membrane and mitochondrial inner membrane. Type example of peptidase family S26. Group: Enzymes. Synonyms: leader peptidase I; signal proteinase. Enzyme Commission Number: EC 3.4.21.89. CAS No. 65979-36-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4180; signal peptidase I; EC 3.4.21.89; 65979-36-4; leader peptidase I; signal proteinase; Escherichia coli leader peptidase; eukaryotic signal peptidase; eukaryotic signal proteinase; leader peptidase; leader peptide hydrolase; leader proteinase; signal peptidase; pilin leader peptidase; SPC; prokaryotic signal peptidase; prokaryotic leader peptidase; HOSP; prokaryotic signal proteinase; propeptidase; PuIO prepilin peptidase; signal peptide hydrolase; signal peptide peptidase; signalase; bacterial leader peptidase 1; pilin leader peptidase. Cat No: EXWM-4180. | |
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