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Procyanidin B3 is a natural product, acts as a specific HAT inhibitor, binds to the other site of p300 instead of the active site, selectively inhibits p300-mediated androgen receptor acetylation. Procyanidin B3 has no effect on HDAC or HMT (histone methyltransferase). Uses: Designed for use in research and industrial production. Additional or Alternative Names: PROCYANIDIN B3;CATECHIN-(4ALPHA->8)-CATECHIN;CATECHIN-(4ALPHA->8)-CATECHIN B3;procyanidin B3 from barley;(2R,2R,3S,3S,4S)-2,2-Bis(3,4-dihydroxyphenyl)-4,8-bichroman-3,3,5,5,7,7-hexol;(2R,2R,3S,3S,4α)-3,3,4,4-Tetrahydro-2α,2α-bis(3,4-dihydroxyphenyl)-4,8-bi[2H-1-benzopyran]-3,3,5,5,7,7-hexol;3,3,4,4-Tetrahydro-2α,2α-bis(3,4-dihydroxyphenyl)-4α,8-bi[2H-1-benzopyran]-3β,3β,5,5,7,7-hexol;(2R,2R,3S,3S,4S)-2,2-Bis(3,4-dihydroxyphenyl)-3,3,4,4-tetrahydro-[4,8-bi-2H-1-benzopyran]-3,3,5,5,7,7-hexol. Product Category: Inhibitors. Appearance: Solid. CAS No. 23567-23-9. Molecular formula: C30H26O12. Mole weight: 578.52. Purity: 0.9963. Canonical SMILES: O[C@@H]1[C@@H](C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3[C@H]1C4=C5C(C[C@H](O)[C@@H](C6=CC=C(O)C(O)=C6)O5)=C(O)C=C4O. Density: 1.705. Product ID: ACM23567239. Alfa Chemistry ISO 9001:2015 Certified.
Procyanidin B3
Procyanidin B3 is a natural product with antioxidant activity and oral bioavailability, possessing good blood-brain barrier penetration. Procyanidin B3 is a selective inhibitor of histone acetyltransferase ( HAT ). By inhibiting p300 HAT -mediated acetylation of the androgen receptor ( androgen receptor ). Procyanidin B3 alleviates intervertebral disc degeneration (IVDD) by inhibiting the formation of the TLR4/MD-2 complex. Procyanidin B3 can be used in research on prostate cancer and arthritis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 23567-23-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2345.