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| Product | Description | |
|---|---|---|
| Propidium iodide | 100mg Pack Size. Group: Stains & Indicators. Formula: C27H34I2N4. CAS No. 25535-16-4. Prepack ID 14137305-100mg. Molecular Weight 668.39. See USA prepack pricing. |  |
| Propidium iodide | 50mg Pack Size. Group: Stains & Indicators. Formula: C27H34I2N4. CAS No. 25535-16-4. Prepack ID 14137305-50mg. Molecular Weight 668.39. See USA prepack pricing. | |
| Propidium Iodide | Propidium Iodide Inhibitor. Uses: Scientific use. Product Category: T2130. CAS No. 25535-16-4. |  |
| Propidium Iodide | Propidium iodide (PI) is a fluorescent dye [FW 668.41] that binds specifically to DNA. This property has led to its common use in evaluation of cell cycle, aneuploidy and apoptosis by flow cytometry. When excited by a laser light at 488 nm, PI emits a signal that can be monitored by the red wavelength detector typically reserved for phycoerythrin (usually FL2). Propidium iodide is excluded from viable cells, thus analysis of DNA content in cells requires membrane permeabilization. In evaluation of apoptosis, PI is used to distinguish necrotic cells or cells in late stages of apoptosis, which have permeabilized membranes and thus bind PI, from viable cells or cells in early apoptosis where membranes are intact and PI is excluded. Group: Biochemicals. Alternative Names: 2,7-Diamino-9-phenyl-10 (diethylaminopropyl)-phenanthridium iodide methiodide. Grades: Molecular Biology Grade. CAS No. 25535-16-4. Pack Sizes: 100mg. US Biological Life Sciences. |  Worldwide |
| Propidium Iodide | Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis ( apoptosis ) or necrosis ( necrosis ), and is often used in flow cytometry analysis. Uses: Scientific research. Group: Fluorescent dye. CAS No. 25535-16-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-D0815. |  |
| Propidium Iodide ≥95% (HPLC) | Propidium Iodide is a phenanthridine compound, a class of compounds with reported activity against several species of trypanosomes. Propidium iodide may be used in flow cytometry to evaluate cell viability when used with other dyes that stain viable cells or cells that are early in the apoptosis process. Propidium iodide (PI) is a fluorescent dye [FW 668.41] that binds specifically to DNA. This property has led to its common use in evaluation of cell cycle, aneuploidy and apoptosis by flow cytometry. When excited by a laser light at 488nm, PI emits a signal that can be monitored by the red wavelength detector typically reserved for phycoerythrin (usually FL2). Propidium iodide is excluded from viable cells, thus analysis of DNA content in cells requires membrane permeabilization. In evaluation of apoptosis, PI is used to distinguish necrotic cells or cells in late stages of apoptosis, which have permeabilized membranes and thus bind PI, from viable cells or cells in early apoptosis whe Group: Biochemicals. Alternative Names: 3, 8-Diamino-5-[3- (diethylmethylammonio) propyl]-6-phenylphenanthridinium Iodide; 3,8-Diamino-5-(3-diethylaminopropyl)-6-phenylphenanthridinium Iodide Methiodide; [3- (3, 8-Diamino-6-phenyl-5-phenanthridinio) propyl]. Grades: Reagent Grade. CAS No. 25535-16-4. Pack Sizes: 25mg, 100mg, 250mg, 1g. US Biological Life Sciences. | Worldwide |
| Propidium Iodide Solution, 1mg/ml | Propidium iodide (PI) is a fluorescent dye [FW 668.41] that binds specifically to DNA. This property has led to its common use in evaluation of cell cycle, aneuploidy and apoptosis by flow cytometry. When excited by a laser light at 488 nm, PI emits a signal that can be monitored by the red wavelength detector typically reserved for phycoerythrin (usually FL2). Propidium iodide is excluded from viable cells, thus analysis of DNA content in cells requires membrane permeabilization. In evaluation of apoptosis, PI is used to distinguish necrotic cells or cells in late stages of apoptosis, which have permeabilized membranes and thus bind PI, from viable cells or cells in early apoptosis where membranes are intact and PI is excluded. Group: Biochemicals. Alternative Names: 3, 8-Diamino-5-[3- (diethylmethylammonio) propyl]-6-phenylphenanthridinium Iodide; 3,8-Diamino-5-(3-diethylaminopropyl)-6-phenylphenanthridinium Iodide Methiodide; [3- (3, 8-Diamino-6-phenyl-5-phenanthridinio) propyl] diethylmethylammonium Diiodide; 3, 8-Diamino-5- (diethyl methyl aminopropyl ) -6-phenylphenanthridinium Diiodide; Propidium Diiodide. Grades: Molecular Biology Grade. CAS No. 25535-16-4. Pack Sizes: 10ml. US Biological Life Sciences. | Worldwide |
| Calcein-AM | Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Calcein acetoxymethyl ester. CAS No. 148504-34-1. Pack Sizes: 1 mg. Product ID: HY-D0041. | |
| Icaritin | Icaritin is unable to promote proliferation, migration and tube-like structure formation by human umbilical vein endothelial cells (HUVECs) in vitro. Icaritin potently inhibited proliferation of K562 cells (IC50 was 8 μM) and primary CML cells (IC50 was 13.4 μM for CML-CP and 18 μM for CML-BC), induced CML cells apoptosis and promoted the erythroid differentiation of K562 cells with time-dependent manner. Furthermore, Icaritin was able to suppress the growth of primary CD34+ leukemia cells (CML) and Imatinib-resistant cells, and to induce apoptosis. Icaritin strongly inhibited the growth of breast cancer MDA-MB-453 and MCF7 cells. At concentrations of 2-3 μM, icaritin induced cell cycle arrest at the G(2)/M phase accompanied by a down-regulation of the expression levels of the G(2)/M regulatory proteins such as cyclinB, cdc2 and cdc25C. Icaritin at concentrations of 4-5 μM, however, induced apoptotic cell death characterized by the accumulation of the annexin V- and propidium iodide-positive cells, cleavage of poly ADP-ribose polymerase (PARP) and down-regulation of the Bcl-2 expression. In mouse leukemia model, Icaritin could prolong lifespan of NOD-SCID nude mice inoculated with K562 cells as effective as Imatinib without suppression of bone marrow. Icaritin could up-regulate phospho-JNK or phospho-C-Jun and down-regulate phospho-ERK, phospho-P-38, Jak-2, phospho-Stat3 and phospho-Akt expression with dose- or time-dependent manner. Synonyms: Anhydroicaritin; 3,5,7-Trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one; 3-hydroxy-7-o-beta-glucose-8-prenyl-4''-methoxy Chrysin. Grades: >98%. CAS No. 118525-40-9. Molecular formula: C21H20O6. Mole weight: 368.38. |  |
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