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3-(Trimethoxysilyl)propyl acrylate is a reactive monomer that is majorly used as a silane coupling agent for the formation of hybrid compounds. It facilitates the formation of a hydrophobic surface by lowering the surface tension and increasing the wettability. Uses: This product is suitable for scientific research. Group: Saltself-assembly materials. Alternative Names: (3-Acryloyloxypropyl)trimethoxysilane. CAS No. 4369-14-6. Pack Sizes: Packaging 5 mL in glass bottle 25 mL in poly bottle. Product ID: 3-trimethoxysilylpropyl prop-2-enoate. Molecular formula: 234.32. Mole weight: H2C=CHCO2(CH2)3Si(OCH3)3. CO[Si](CCCOC(=O)C=C)(OC)OC. 1S/C9H18O5Si/c1-5-9 (10)14-7-6-8-15 (11-2, 12-3)13-4/h5H, 1, 6-8H2, 2-4H3. KBQVDAIIQCXKPI-UHFFFAOYSA-N. ≥97%.
4-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthalenol Hydrochloride (Duloxetine Impurity). Uses: For analytical and research use. Group: Impurity standards. CAS No. 953028-76-7. IUPAC Name: 4-[3-(methylamino)-1-(2-thienyl)propyl]naphthalen-1-ol;hydrochloride. Molecular Formula: C18H19NOS.ClH. Mole Weight: 333.88. Catalog: APS953028767. SMILES: Cl.CNCCC(c1cccs1)c2ccc(O)c3ccccc23. Format: Neat.
4-Methyl-1,3,2-dioxathiolane 2-Oxide (mixture of isomers)
1,2-Propyleneglycol sulfide (1,3-PS) can be used as a film-forming additive for the formation of a solid electrolytic interface for the fabrication of high-performance lithium-ion batteries. It is also used as a solvent for making non-aqueous electrolytes for lithium ion and lithium sulfur batteries. Group: Battery materials. Alternative Names: 1,2-Propanediol Cyclic Sulfite (mixture of isomers). CAS No. 1469-73-4. Product ID: 4-methyl-1,3,2-dioxathiolane 2-oxide. Molecular formula: 122.14. Mole weight: C3H6O3S. CC1COS(=O)O1. InChI=1S/C3H6O3S/c1-3-2-5-7 (4)6-3/h3H, 2H2, 1H3. SJHAYVFVKRXMKG-UHFFFAOYSA-N. >98.0%(GC).
4-Vinylphenol (10% in Propylene glycol)
4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 4-Hydroxystyrene. CAS No. 2628-17-3. Pack Sizes: 100 mg (832.2 mM * 1 mL in Propylene glycol). Product ID: HY-W005288.
6,6-Dimethyl-2-propyl-3-[[4-[2-(2-trityltetrazol-5-yl)phenyl]phenyl]methyl]furo[3,4-d]imidazol-4-one. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1048948-15-7. IUPAC Name: 6,6-dimethyl-2-propyl-3-[[4-[2-(2-trityltetrazol-5-yl)phenyl]phenyl]methyl]furo[3,4-d]imidazol-4-one. Molecular Formula: C43H38N6O2. Mole Weight: 670.80. Catalog: APS1048948157. SMILES: CCCc1nc2c (C (=O)OC2 (C)C)n1Cc3ccc (cc3)c4ccccc4c5nnn (n5)C (c6ccccc6) (c7ccccc7)c8ccccc8. Format: Neat.
A37
A37 is an aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor (IC50 = 4.6 μM; Ki = 300 nM). It competitively binds to the aldehyde binding pocket of ALDH1A1, resulting in the disruption of spheroid formation and a decrease of cell viability in ovarian cancer cells in vitro. Synonyms: Ethyl 2-[[3, 4-dihydro-4-oxo-3-[3- (1-pyrrolidinyl) propyl][1]benzothieno[3, 2-d]pyrimidin-2-yl]thio]acetate; CM037; CM-037; CM 037; A37; A-37; A 37. Grades: ≥97% by HPLC. CAS No. 896795-60-1. Molecular formula: C21H25N3O3S2. Mole weight: 431.57.
Albendazole
United States Pharmacopeia (USP) Reference Standard. Uses: For analytical and research use. Group: Pharmacopeia & metrological institutes standards; pharma & vet compounds & metabolites; standards for environmental regulatory methods; pharma & vet compounds & metabolites; api standards; british pharmacopoeia; european pharmacopoeia (ph. eur.); pharmaceutical toxicology; pharmacopoeial standards. Alternative Names: SKF-62979,Albendazole. CAS No. 54965-21-8. Pack Sizes: 200MG. IUPAC Name: methyl N-(5-propylsulfanyl-1H-benzimidazol-2-yl)carbamate. Molecular Formula: C12H15N3O2S. Mole Weight: 265.33. Catalog: APS54965218. SMILES: CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1. Format: Neat.
Alpha-Hydroxy Olopatadine (>90%). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 11-[3-(Dimethylamino)propylidene]-6,11-dihydro-α-hydroxydibenz[b,e]oxepin-2-acetic Acid, α-Hydroxyolopatadine. CAS No. 1331822-32-2. IUPAC Name: 2-[11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]-2-hydroxyacetic acid. Molecular Formula: C21H23NO4. Mole Weight: 353.41. Catalog: APS1331822322. SMILES: CN (C)CCC=C1c2ccccc2COc3ccc (cc13)C (O)C (=O)O. Format: Neat.
Alpha-Hydroxy Olopatadine Hydrochloride
Alpha-Hydroxy Olopatadine Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 11-[3-(Dimethylamino)propylidene]-6,11-dihydro-α-hydroxydibenz[b,e]oxepin-2-acetic Acid Hydrochloride (1:1). CAS No. 1331668-21-3. IUPAC Name: 2-[11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]-2-hydroxyacetic acid;hydrochloride. Molecular Formula: C21H23NO4.ClH. Mole Weight: 389.87. Catalog: APS1331668213. SMILES: Cl. CN (C)CCC=C1c2ccccc2COc3ccc (cc13)C (O)C (=O)O. Format: Neat.
(±)-Propylene Oxide
(±)-Propylene Oxide is a carcinogenic substance to rats and potentially humans (1). (±)-Propylene oxide also has the ability to self-polymerize at room temperature in the presence of powdered potassium hydroxide (2). (±)-Propylene oxide is used in industry for fumigation in the food industry, inducing the formation of persistent toxic chlorohydrins. Group: Biochemicals. Grades: Highly Purified. CAS No. 75-56-9. Pack Sizes: 50ml, 250ml. Molecular Formula: C3H6O, Molecular Weight: 58.08. US Biological Life Sciences.
Worldwide
BACE-1 Inhibitor
BACE-1 Inhibitor is a potent, selective and cell-permeable inhibitor of human β-secretase (BACE-1) binding to the active site of BACE-1. It inhibits secretion of amyloid-β (Aβ) precursor protein (APP; IC50 = 29 nM) in HEK293T cells and also suppresses formation of the Aβ peptides Aβ38, Aβ40, and Aβ42 in primary chick neurons (IC50s = 3.7, 4.7, and 4.8 nM, respectively). Synonyms: BACE-1 Inhibitor; BACE 1 Inhibitor; BACE1 Inhibitor; Beta-Secretase Inhibitor IV; β-Secretase Inhibitor IV; N1-[(1S,2R)-3-(Cyclopropylamino)-2-hydroxy-1-(phenylmethyl)propyl]-5-[methyl(methylsulfonyl)amino]-N3-[(1R)-1-phenylethyl]-1,3-benzenedicarboxamide; Axon 1125. Grades: 98%. CAS No. 797035-11-1. Molecular formula: C31H38N4O5S. Mole weight: 578.72.
BrettPhos
Ligand for palladium-catalyzed cross-coupling reactions using aryl mesylates with electron-deficient anilines. Ligand for palladium-catalyzed cross-coupling of primary arylamines at low catalyst loading. Ligand for palladium-catalyzed cross-coupling of aryl iodides and primary amines. Ligand for the Suziki-Miyaura coupling of tosylates and mesylates. Ligand for the palladium-catalyzed trifluoromethylation of aryl chlorides. Ligand for the palladium-catalyzed formation of aryl-SCF3 compounds from aryl bromides. Ligand for the nickel-catalyzed cross-coupling of styrenyl epoxides with boronic acids. Ligand for the palladium-catalyzed intramolecular CH difluoroalkylation. Group: Organic phosphine compounds. Alternative Names: C35H53O2P; dicyclohexyl-(2',4',6'-triisopropyl-3,6-dimethoxy-biphenyl-2-yl)-phosphane; BrettPhos; 2-(Dicyclohexylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl; ZINC43220891; ST24046493; 2-DICYCLOHEXYLPHOSPHINO-2',4',6'-TRIISOPROPYL-3,6-DIMETHOXYBIPHENYL; AS-19342; 2-(Dicyclohexylphosphino)3,6-dimethoxy-2 inverted exclamation marka,4 inverted exclamation marka,6 inverted exclamation. CAS No. 1070663-78-3. Molecular formula: C35H53O2P. Mole weight: 536.781g/mol. IUPACName: dicyclohexyl-[3,6-dimethoxy-2-[2,4,6-tri(propan-2-yl)phenyl]phenyl]phosphane. Canonical SMILES: CC (C)C1=CC (=C (C (=C1)C (C)C)C2=C (C=CC (=C2P (C3CCCCC3)C4CCCCC4)OC)OC)C (C)C. Catalog: ACM1070663783.
CK0106023 was specific inhibitor of KSP. In tumor-bearing mice, CK0106023 exhibited antitumor activity comparable to or exceeding that of paclitaxel and caused the formation of monopolar mitotic figures identical to those produced in cultured cells. KSP was most abundant in proliferating human tissues and was absent from cultured postmitotic neurons. Synonyms: CK 0106023; CK-0106023; N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)propyl)-4-bromo-N-(3-(dimethylamino)propyl)benzamide. CAS No. 336115-72-1. Molecular formula: C30H32BrClN4O2. Mole weight: 595.97.
DL-Propylhexedrine Hydrochloride. Uses: For analytical and research use. Group: Chiral molecules. Alternative Names: N, alpha -dimethyl-cyclohexaneethylamine hydrochloride, (+/-)-Propylhexedrine hydrochloride, Propylhexedrine hydrochloride,N,alpha-Dimethyl-cyclohexaneethanamine hydrochloride, Cyclohexyl(isopropyl)methylammonium chloride, NSC 27110, Eventin hydrochloride, dl-Propylhexedrine hydrochloride, N, alpha -dimethyl-cyclohexaneethylamine hydrochloride, Benzedrex hydrochloride, Cyclohexylisopropylmethylamine hydrochloride, NSC 170998. CAS No. 1007-33-6. IUPAC Name: 1-cyclohexyl-N-methylpropan-2-amine;hydrochloride. Molecular Formula: C10H21N.ClH. Mole Weight: 191.74. Catalog: APS1007336. SMILES: Cl.CNC(C)CC1CCCCC1. Format: Neat.
(E)-Olopatadine Hydrochloride
(E)-Olopatadine Hydrochloride. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (11E)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic Acid Hydrochloride (1:1), (E)-Olopatadine Hydrochloride. CAS No. 949141-22-4. IUPAC Name: 2-[(11E)-11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]acetic acid;hydrochloride. Molecular Formula: C21H23NO3.ClH. Mole Weight: 373.87. Catalog: APS949141224. SMILES: Cl. CN (C)CC\C=C\1/c2ccccc2COc3ccc (CC (=O)O)cc13. Format: Neat.
Fananserin
Fananserin is a 5-HT2A receptor and a dopamine D4 receptor antagonist (Ki = 0.26, 2.93, 25, 38, 70 and 726 nM for 5-HT2A, D4, H1, α1, 5-HT1A and D2 receptors, respectively). Fananserin inhibits 5-HT-induced inositol phosphate formation in vitro (IC50 = 7.76 nM), and antagonizes mescaline-induced head twitches in vivo. Synonyms: Fananserin; RP 62203; RP-62203; RP62203; 2-[3-[4-(4-Fluorophenyl)-1-piperazinyl]propyl]-2H-naphthyl[1,8-cd]isothiazole-1,1-dioxide. Grades: ≥99% by HPLC. CAS No. 127625-29-0. Molecular formula: C23H24FN3O2S. Mole weight: 425.52.
Hydroxypropyl Betadex
Hydroxypropyl betadex occurs as a white or almost white, amorphous or crystalline powder. Synonyms: Cavasol W7; 2-hydroxypropyl-b-cyclodextrin; 2-hydroxypropyl cyclomaltoheptaose; hidroksipropilbetadeksas; hydoxipropylbeta- dex; hydroksipropylbetadeksi; hydroxypropylbetadeksum; hydro- xypropylbetadexum; Kleptose HPB. CAS No. 128446-35-5. Product ID: PE-0341. Molecular formula: C42H70O35(C3H6O)x. Category: Solubilizing Agents; Stabilizing Agents. Product Keywords: Excipients; Stabilizers; PE-0341; Hydroxypropyl Betadex; Solubilizing Agents; Stabilizing Agents; C42H70O35(C3H6O)x; 128446-35-5. UNII: 1I96OHX6EK. Chemical Name: β-Cyclodextrin, 2-hydroxypropyl ether. Grade: Pharmceutical Excipients. Administration route: Injectable. Dosage Form: Injectable preparation. Stability and Storage Conditions: Store in well-closed containers. Source and Preparation: Hydroxypropyl betadex is prepared by the treatment of an alkaline solution of β-cyclodextrin with propylene oxide. The substitution pattern can be influenced by varying the pH. Formation of O-6 and O-2 substituted products is favored by high and low alkali concentration, respectively. The mixture of products produced may be refined by preparative chromatography. Applications: Hydroxypropyl betadex has been widely investigated in pharmaceutics and has principally been used as a solubilizer for hydrophobic molecules in oral liquids, oral solids, parente
LY2334737
LY2334737 is an orally available valproic acid ester of gemcitabine, which is a broad-spectrum antimetabolite with antineoplastic activity. It is an orally available prodrug of gemcitabine which is a nucleoside analog used as chemotherapy. It is hydrolyzed by carboxylesterase 2 (CES2) and releases gemcitabine systemically over a period of time consistent with formation rate-limited kinetics. It was less cytotoxic to a SK-OV-3 CES2 knockdown than parental cells. Uses: Ly2334737 is used as chemotherapy. it has antineoplastic activity. Synonyms: LY2334737; LY 2334737; LY-2334737; gemcitabine prodrug; 2'-Deoxy-2',2'-difluoro-N-(1-oxo-2-propylpentyl)cytidine;N-[1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]-2-propylpentanamide. Grades: >98 %. CAS No. 892128-60-8. Molecular formula: C17H25F2N3O5. Mole weight: 389.39.
Methanesulfonato(2-(di-t-butylphosphino)-3-methoxy-6-methyl-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II), min. 98% [RockPhos Palladacycle Gen. 3]
Palladium precatalyst used for the arylation of an aliphatic alcohol. Palladium precatalyst used for the synthesis of diaryl ethers under mild conditions. Palladium precatalyst used for the intermolecular C-O bond formation with secondary and primary alcohols. Group: Palladium catalysts. Alternative Names: RockPhos Pd G3;[RockPhos Palladacycle]; MFCD27952542; 2009020-38-4; Methanesulfonato(2-(di-t-butylphosphino)-3-methoxy-6-methyl-2', 4', 6'-tri-i-propyl-1, 1'-biphenyl)(2'-amino-1, 1'-biphenyl-2-yl)palladium(II). CAS No. 2009020-38-4. Molecular formula: C44H63NO4PPdS-. Mole weight: 839.445g/mol. IUPACName: ditert-butyl-[6-methoxy-3-methyl-2-[2, 4, 6-tri(propan-2-yl)phenyl]phenyl]phosphane; methanesulfonic acid;palladium;2-phenylaniline. Canonical SMILES: CC1=C (C (=C (C=C1)OC)P (C (C) (C)C)C (C) (C)C)C2=C (C=C (C=C2C (C)C)C (C)C)C (C)C. CS (=O) (=O)O. C1=CC=C ([C-]=C1)C2=CC=CC=C2N. [Pd]. Catalog: ACM2009020384.
n-Propylammonium Iodide. Uses: The iodide and bromide based alkylated halides find applications as precursors for fabrication of perovskites for photovoltaic applications.n-propylammonium iodide (pai) is used as an additive for the formation of perovskite films. the film can be further used in the fabrication of perovskite solar cells (psc) with an efficiency of ~11.3%. Group: Perovskite materials. Alternative Names: Propanamine hydrIodide, Propylammonium Iodide, greatcell Solar. CAS No. 14488-45-0. Pack Sizes: 5 g/25 g. Product ID: propan-1-amine; hydroiodide. Molecular formula: 187.02 g/mol. Mole weight: C3H10IN. CCCN.I. InChI=1S/C3H9N.HI/c1-2-3-4;/h2-4H2, 1H3;1H. GIAPQOZCVIEHNY-UHFFFAOYSA-N.
O-Desisobutyl-O-n-propyl Febuxostat
O-Desisobutyl-O-n-propyl Febuxostat. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Febuxostat Impurity 22. CAS No. 1530308-87-2. Pack Sizes: 10MG. IUPAC Name: 2-(3-cyano-4-propoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid. Molecular Formula: C15H14N2O3S. Mole Weight: 302.35. Catalog: APS1530308872. SMILES: CCCOc1ccc(cc1C#N)c2nc(C)c(s2)C(=O)O. Format: Neat. Shipping: Room Temperature.
Olmesartan Acid
Olmesartan Acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Olmesartan, Olmesartan Acid,Olmesartan Medoxomil Imp. A (EP), 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-imidazole-5-carboxylic Acid. CAS No. 144689-24-7. IUPAC Name: 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid. Molecular Formula: C24H26N6O3. Mole Weight: 446.50. Catalog: APS144689247. SMILES: CCCc1nc (c (C (=O)O)n1Cc2ccc (cc2)c3ccccc3c4nnn[nH]4)C (C) (C)O. Format: Neat.
Olmesartan Acid Ethyl Ester
Olmesartan Acid Ethyl Ester. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Acid Ethyl Ester, Olmesartan Ethyl Ester. CAS No. 144689-23-6. IUPAC Name: ethyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate. Molecular Formula: C26H30N6O3. Mole Weight: 474.55. Catalog: APS144689236. SMILES: CCCc1nc (c (C (=O)OCC)n1Cc2ccc (cc2)c3ccccc3c4nnn[nH]4)C (C) (C)O. Format: Neat.
Olmesartan Lactone Impurity
Olmesartan Lactone Impurity. Uses: For analytical and research use. Group: Impurity standards. CAS No. 849206-43-5. IUPAC Name: 6,6-dimethyl-2-propyl-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]furo[3,4-d]imidazol-4-one. Molecular Formula: C24H24N6O2. Mole Weight: 428.49. Catalog: APS849206435. SMILES: CCCc1nc2c (C (=O)OC2 (C)C)n1Cc3ccc (cc3)c4ccccc4c5nnn[nH]5. Format: Neat.