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| Product | Description | |
|---|---|---|
| Protein kinase inhibitor 1 hydrochloride | Protein kinase inhibitor 1 hydrochloride is a potent HIPK2 inhibitor, with IC 50 s of 136 and 74 nM for HIPK1 and HIPK2, and a K d of 9.5 nM for HIPK2. Uses: Scientific research. Group: Signaling pathways. CAS No. 2321337-71-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00439A. |  |
| Protein kinase inhibitor 6 | Protein kinase inhibitor 6 is a protein kinase inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 348-45-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-47026. | |
| Protein Kinase Inhibitor CKI-7 (PKI) (N-(2-aminoethyl)-5-chloro-isoquinoline-8-sulfonamide) | A potent inhibitor against casein kinase 1 with respect to ATP. Exhibits a much weaker effect on casein kinase 2 and other protein kinases. Group: Biochemicals. Alternative Names: N-(2-aminoethyl)-5-chloro-isoquinoline-8-sulfonamide. Grades: Molecular Biology Grade. CAS No. 120615-25-0. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Protein Kinase Inhibitor from rabbit | ?85% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Protein Kinase Inhibitor H-7 (PKI) (1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride) | A selective inhibitor of protein kinase C or cyclic-nucleotide-dependent protein kinases. Group: Biochemicals. Alternative Names: 1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride. Grades: Molecular Biology Grade. CAS No. 108930-17-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Protein Kinase Inhibitor H-89 (PKI, N- (2-p-bromocinnamyl aminoeth yl ]-5-isoquinolinesulfonamid e ) (N- (2-p-bromocinnamyl aminoeth yl ]-5-isoquinolinesulfonamid e ) | Protein Kinase Inhibitors. Group: Biochemicals. Grades: Molecular Biology Grade. CAS No. 127243-85-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Protein Kinase Inhibitor H-8 (PKI) (N- [2-( methyl amino) ethy l ]-5-isoquinolinesulfonamid e dihydrochloride) | Inhibits cyclic-nucleotide-dependent protein kinases. Group: Biochemicals. Alternative Names: N- [2-( methyl amino) ethy l ]-5-isoquinolinesulfonamid e dihydrochloride. Grades: Molecular Biology Grade. CAS No. 84478-11-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Protein Kinase Inhibitor H-9 (PKI) (N- (2-aminoethyl ) -5-isoquinolinesulfonamid e dihydrochloride) | Competitive inhibitor of protein kinase C, cGMP- and cAMP-dependent protein kinases with respect to ATP binding. Group: Biochemicals. Alternative Names: N- (2-aminoethyl ) -5-isoquinolinesulfonamid e dihydrochloride. Grades: Molecular Biology Grade. CAS No. 84468-17-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Protein Kinase Inhibitor HA1004 (PKI) (N- (2-guanidinoethyl ] -5-isoquinolinesulfonamid e dihydrochloride) | Calcium antagonist and vasodilator. Does not affect on cardiac function. Group: Biochemicals. Alternative Names: N- (2-guanidinoethyl ] -5-isoquinolinesulfonamid e dihydrochloride. Grades: Molecular Biology Grade. CAS No. 92564-34-6. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Protein Kinase Inhibitor ML-7 (PKI) (1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride) | Inhibits myosin light chain kinase. Group: Biochemicals. Alternative Names: 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride. Grades: Molecular Biology Grade. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Protein Kinase Inhibitor ML-9 (PKI) (1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride) | Competitive inhibitor of several protein kinases wrt ATP. Group: Biochemicals. Alternative Names: 1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride. Grades: Molecular Biology Grade. CAS No. 105637-50-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Protein Kinase Inhibitors 1 | Protein Kinase Inhibitors 1 is a HIPK2 inhibitor with IC50 of 74 nM and Kd of 9.5 nM. Synonyms: 2,4-Thiazolidinedione, 5-[[1,2-dihydro-2-oxo-6'-(1-piperazinyl)[3,3'-bipyridin]-5-yl]methylene]-; 5-((2-oxo-6'-(piperazin-1-yl)-1,2-dihydro-[3,3'-bipyridin]-5-yl)methylene)thiazolidine-2,4-dione; 5-[[1,2-Dihydro-2-oxo-6'-(1-piperazinyl)[3,3'-bipyridin]-5-yl]methylene]-2,4-thiazolidinedione. Grades: ≥95%. CAS No. 1365986-44-2. Molecular formula: C18H17N5O3S. Mole weight: 383.43. |  |
| BMP Inhibitor III, LDN-212854 (Abl Inhibitor V, LDN212854, Bone Morphogenetic Protein Inhibitor III, PDGFR Tyrosine Kinase Inhibitor XXIV, RIP2 Inhibitor I, RIPK2 Inhibitor I, 5-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline) | A cell-permeable pyrazolopyrimidinyl quinoline that is superior to Dorsomorphin and DMH1 as an ATP-site-targeting, ALK1/2 inhibitor (IC50 = 2.40 and 1.30nM, respectively; [ATP] = 6uM) with respect to both potency and selectivity over ALK3/4/5 (IC50 = 0.858, 2.133, and 9.276uM, respectively). Also a potent RIPK2 inhibitor (IC50 = 6nM) with reduced potency against ABL1/c-abl, PDGFR-beta, ALK3, and PDGFR-alpha (IC50 = 40, 68, 85.8, and 650nM, respectively) and little inhibitory activity toward a panel of more than 190 kinases. Effectively inhibits ALK2- and ALK3-mediated C2C12 osteogenic differentiation (IC50 = 10 and 40.5nM, respectively) in vitro and prevents constitutively active ALK2 Q207D mutant-induced heterotopic ossification in mice (6mg/kg/12h via i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??N?. US Biological Life Sciences. | Worldwide |
| CaMKII Inhibitor XII (Ca2+/Calmodulin-Dependent Protein Kinase II Inhibitor XII) | A pyrimidinyl sulfonamide compound that acts as a potent, reversible and CaM non-competitive inhibitor of CaMKII activities (IC50 = 0.063uM) with excellent selectivity over several kinases (IC50 = >60, 36, 11, 30 and 21uM for CaMKIV, MLCK, p38alpha, Akt1 and PKC, respectively). Shown to exhibit ~25-fold greater potency towards CaMKII than the CaM-competitive inhibitor KN-93. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| CID 2011756 (Pan Protein Kinase D (PKD) Inhibitor, Cell Permeable, 5- (3-Chlorophenyl) -N-[4- (4-morpholinylmethyl) phenyl]-2-furancarboxamide) | Protein kinase D (PKD) inhibitor (IC50 values are 0.6, 0.7 and 3.2um for PKD2, PKD3 and PKD1 respectively). Cell permeable (EC50=10um for PKD1 inhibition). ATP-competitive. Group: Biochemicals. Grades: Highly Purified. CAS No. 638156-11-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Haspin Kinase Inhibitor, CHR-6494 (3-(1H-Indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine, Haploid Germ Cell-Specific Nuclear Protein Kinase Inhibitor, CHR-6494, Indazolyl-propylimidazopyridazin-amine) | A cell-permeable indazolyl imidazopyridazinamine compound that acts as a potent and reversible inhibitor of histone kinase haspin activity (IC50 = 2nM) with moderate selectivity over TrkA, GSK-3beta, PIM1, Cdk1/B and Cdk2/A (% inhibition at 100nM = 58, 48, 36, 34 and 33, respectively) among a panel of 27-kinases. Shown to block pH3-Thr3, with no effect on pH3-Ser10 and pH3-Ser28, cause mitotic catastrophe, upregulate BUB1 and cyclin B1 levels, and potently induce apoptosis (IC50 = 473, 500 and 752nM in HeLa, HCT-116 and MDA-MB-231 cells, respectively). Further, efficiently blocks bFGF-induced sprouting vessel by 70% at 1uM (chicken embryo aortic arch ring assay) and suppresses tumor growth in HCT-116 xenografted mouse model (50mg/kg, i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| MLKL Inhibitor, Necrosulfonamide ((E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide, Mixed Lineage Kinase Domain-like Protein Inhibitor, Necrosome Inhibitor II, Necrosulfonamide) | A cell-permeable acrylamide compound that inhibits human, but not murine, MLKL adaptor function via covalent modification of Cys86 and is more potent than Nec-1 in preventing necrotic/necroptotic death in human HT-29 (IC50 = 124nM and 2uM, respectively), being ineffective against necrosis/necroptosis in murine L929 or apoptosis in human RIP3-null Panc-1 cells. Unlike Nec-1, which prevents necrosome formation by blocking RIP1-RIP3 interaction, MLKL prevents the MLKL-RIP1-RIP3 necrosome complex from interacting with further downstream effectors. Group: Biochemicals. Grades: Highly Purified. CAS No. 432531-71-0. Pack Sizes: 25mg. Molecular Formula: C??H??N?O?S?, Primary Target: human MLKL. US Biological Life Sciences. | Worldwide |
| MNK1/2 Inhibitor II, ETP-45835 (ETP45835?MNK Inhibitor II, Mitogen-Activated Protein Kinase-Interacting Kinase Inhibitor II) (4-(3-(Piperidin-4-yl)-1H-pyrazol-5-yl)pyridine, diHCl) | A cell-permeable 3,5-disubstituted pyrazolo compound that acts as a selective MNK inhibitor (IC50=646 and 575nM, respectively, against MNK1 and MNK2) with much reduced or little activity against 24 other kinases (<15% inhibition at 5uM). Reported to exhibit good aqueous solubility (>100uM at pH 7.4) and inhibit the proliferation (IC50=17uM) and cellular eIF4E Ser209 phosphorylation (IC50=4.7uM) of MV4:11 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N? 2HCl. US Biological Life Sciences. | Worldwide |
| PKR Inhibitor III, 7DG (Double-stranded RNA-activated Protein Kinase Inhibitor III, EIF2AK2 Inhibitor III, 7-Desacetoxy-6,7-dehydrogedunin, Double-stranded RNA-dependent Protein Kinase Inhibitor III) | A cell-permeable gedunin analog that directly targets PKR via reversible interaction inhibits PKR-mediated cellular events by disrupting PKR signaling complexes assembly, such as IkK complex and inflammasome / pyroptosome, resulting in effective blockage of LPS-induced IkBbeta degradaion (20uM) and protection against anthrax toxin LT-induced caspase-1 activation as well as subsequent pyroptosis (10uM) in murine macrophage J774 cultures. PKR is also known to mediate LT-induced apoptosis via its kinase activity in LPS-primed Macrophages derived from C57BL/6 with a resistent NLRP1 allele, inhibitable by C16, but not by 7DG, while LT-induced pyroptosis in J774 cultures is insensitive to C16 treatment. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |
| Protein Kinase A inhibitor fragment 14-22, myristoylated trifluoroacetate salt | ?90% (HPLC), lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Protein kinase A inhibitor fragment 5-24 amide trifluoroacetate salt | ?95% (HPLC), lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| Protein Kinase C Inhibitor, Myristoylated | ?7.5 mg/mL (peptide and counter ion), ?95% (Minimum peptide content 70%, HPLC), aqueous solution (neutral pH). Group: Fluorescence/luminescence spectroscopy. | |
| SRPK Inhibitor, SRPIN340 (N- (2-Piperidin-1-yl-5- (trifluoromethyl) phenyl) isonicotinamide, Serine-Arginine-Rich Protein Kinase Inhibitor, SR Protein Kinase Inhibitor, SR Protein Phosphorylation Inhibitor 340, (SRPIN)340) | A cell-permeable isonicotinamide that acts as an ATP-competitive SRPK1-selective inhibitor (IC50 = 0.14 and 1.8uM, respectively, against mSRPK1 and mSRPK2) with much reduced activity against 143 other kinases. Shown to effectively counteract IGF-1-induced anti-angiogenic to pro-angiogenic VEGF isoforms switch both in cultures in vitro (1h 10uM SRPIN340 prior to 12h IGF-1 stimulation of PCIPs) and in a murine hypoxia-induced retinal neovascularization model in vivo (10pmol/uL/eye intraocular SRPIN340 injection) by inhibiting PKC/SRPK signaling-dependent, alternate splicing factor ASF- (SF2; splicing factor 2) mediated VEGF pro-mRNA PSS (proximal splice site) selection. Suppresses RNA virus Sindbis propagation (IC50 = 60uM in Vero cultures) and HCV-JFH1 replication (1 & 10uM SRPIN340 in Huh7.5.1 cultures). Exhibits no toxicity toward rats (2g/kg p.o. for 2 wks), CHO (5mg/ml for 24h), or Huh7 (30uM for 48h). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 10-DEBC hydrochloride | 10-DEBC hydrochloride is a selective and reversible Akt/PKB inhibitor suppressing the IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), and inhibiting downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. 10-DEBC hydrochloride inhibits cell growth (IC50 ~ 2-6 μM) and leads to apoptosis in rhabdomyosarcoma cells. Synonyms: 10H-Phenoxazine-10-butanamine, 2-chloro-N,N-diethyl-, hydrochloride (1:1); Akt Inhibitor X; 2-Chloro-N,N-diethyl-10H-phenoxazine-10-butanamine hydrochloride; 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride; 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride. Grades: ≥99% by HPLC. CAS No. 925681-41-0. Molecular formula: C20H25N2OCl.HCl. Mole weight: 381.34. | |
| 10-DEBC hydrochloride | Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5uM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ~ 2-6uM) and induces apoptosis in rhabdomyosarcoma cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 925681-41-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C20H25N2OCl.HCl, Method for Determining. US Biological Life Sciences. | Worldwide |
| 10Z-Hymenialdisine | Insecticidal and cytotoxic. Potent NF-kappaB inhibitor. Inhibits various pro-inflammatory cytokines such as IL-1, IL-2, IL-6, IL-8, TNF-alpha and nitric oxide (NO) in a variety of cell lines. ATP-competitive kinase inhibitor. Inhibits DNA damage checkpoint at G2, cyclin-dependent kinases CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, CDK5/p25, GSK-3beta and casein kinase 1 (CK1). Potent mitogen-activated protein kinase kinase-1 (MEK-1) inhibitor. MARK (microtubule affinity-regulating kinase) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 82005-12-7. Pack Sizes: 500ug, 1mg. Molecular Formula: C??H??BrN?O?, Method for Determining. US Biological Life Sciences. | Worldwide |
| 10Z-Hymenialdisine (Hymenialdisine, 4-(2-Amino-4-oxo-2-imidazolidin-5-ylidene)-2-bromo-4,5,6,7-tetrahydropyrrolo[2,3-c]azepin-8-one) | Isolated from sponge Axinella carteri. A potent inhibitor of mitogen-activated protein kinase kinase-1 (MEK-1) (IC50=6nm). Blocks the in vivo phosphorylation of the microtubule-binding protein tau at sites that are hyperphosphorylated by glycogen synthase kinase-b (GSK-3b) and CDK5/p35 in Alzheimers disease. Inhibitor of DNA damage checkpoint at G2 phase (IC50=6uM), cyclin-dependent kinases CDK1/cyclin B (IC50=22nm), CDK2/cyclin A (IC50=70 nm), CDK2/cyclin E (IC50=40nm), CDK4/cyclin D1 (IC50 = 600nm), CDK5/p25 (IC50=28nm), GSK-3b (IC50=10nm), and casein kinase 1 (CK1) (IC50=35nm). Group: Biochemicals. Grades: Highly Purified. CAS No. 82005-12-7. Pack Sizes: 250ug, 1mg. US Biological Life Sciences. | Worldwide |
| 1,1,1-Trifluoro-methanesulfonic Acid 3-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-1-cyclohexen-1-yl Ester | 1,1,1-Trifluoro-methanesulfonic Acid 3-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-1-cyclohexen-1-yl Ester is an intermediate in synthesizing tert-Butyl (3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)carbamate (T302650), which is a reactant in the preparation of furo[3,2-c]pyridine derivatives as protein kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1803033-60-4. Pack Sizes: 25mg, 50mg. Molecular Formula: C12H18F3NO5S. US Biological Life Sciences. | Worldwide |
| 1,1,1-Trifluoro-methanesulfonic Acid 5-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-1-cyclohexen-1-yl Ester | 1,1,1-Trifluoro-methanesulfonic Acid 5-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-1-cyclohexen-1-yl Ester is an intermediate in synthesizing tert-Butyl (3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-en-1-yl)carbamate (T302650), which is a reactant in the preparation of furo[3,2-c]pyridine derivatives as protein kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1803033-59-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C12H18F3NO5S. US Biological Life Sciences. | Worldwide |
| 1, 1, 1-Trifluoromethane sulfonic Acid (E) -4-[1-[4-[2- (Dimethylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl Ester | 1, 1, 1-Trifluoromethane sulfonic Acid (E) -4-[1-[4-[2- (Dimethylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl Ester is an impurity of Tamoxifen (T006000), a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1370699-80-1. Pack Sizes: 5mg, 25mg. Molecular Formula: C27H28F3NO4S. US Biological Life Sciences. | Worldwide |
| (±) -1, 2-Diphenyl-1-[2-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol | (±) -1, 2-Diphenyl-1-[2-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol is an impurity of Tamoxifen (T006000); a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: C26H31NO2, Molecular Weight: 389.53. US Biological Life Sciences. | Worldwide |
| (±) -1, 2-Diphenyl-1-[2-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol-d5 | (±) -1, 2-Diphenyl-1-[2-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol-d5 is the isotope labelled analog of (±) -1, 2-Diphenyl-1-[2-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol (D489855); an impurity of Tamoxifen (T006000) which is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C26H26D5NO2, Molecular Weight: 394.56. US Biological Life Sciences. | Worldwide |
| (±) -1, 2-Diphenyl-1-[4-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol | (±) -1, 2-Diphenyl-1-[4-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol is an impurity of Tamoxifen (T006000); a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. CAS No. 748-97-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C26H31NO2, Molecular Weight: 389.53. US Biological Life Sciences. | Worldwide |
| (±) -1, 2-Diphenyl-1-[4-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol-d5 | (±) -1, 2-Diphenyl-1-[4-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol-d5 is the isotope labelled analog of (±) -1, 2-Diphenyl-1-[4-[2- (dimethylamino) ethoxy]phenyl]butan-1-ol (D489850); an impurity of Tamoxifen (T006000) which is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C26H26D5NO2, Molecular Weight: 394.56. US Biological Life Sciences. | Worldwide |
| 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate | Protein kinase inhibitors. Synonyms: 2-(2-methyl-5-nitrophenyl)guanidine;nitric acid; 2-(2-methyl-5-nitrophenyl)guanidine;nitric acid. Grades: > 95 %. CAS No. 152460-08-7. Molecular formula: C8H11N5O5. Mole weight: 257.20. | |
| 12(S)-HpETE | 12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It mediates the inhibitory synaptic response to FMRF-amide in Aplysia sensory neurons6 and inhibits Ca2+/calmodulin-dependent protein kinase II from rat brain cortex. Synonyms: 12-Hydroperoxyicosatetraenoate; (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoic acid. Grades: ≥98%. CAS No. 71774-10-2. Molecular formula: C20H32O4. Mole weight: 336.5. | |
| 1-(3-Aminopropyl)imidazole | 1-(3-Aminopropyl)imidazole is a reagent used in drug designs and also in the synthesis of novel protein kinase R inhibitors compound and its anti-apoptotic effect on human MCF-7 breast cancer cells by molecular modeling method. Group: Biochemicals. Grades: Highly Purified. CAS No. 5036-48-6. Pack Sizes: 1g, 5g. Molecular Formula: C6H11N3, Molecular Weight: 125.17. US Biological Life Sciences. | Worldwide |
| 1, 3-Benzodioxol-5-yl[4- (2-chloroethoxy) phenyl]methanone | 1, 3-Benzodioxol-5-yl[4- (2-chloroethoxy) phenyl]methanone is a metabolite of Tamoxifen (T006000), a selective estrogen response modifier, protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. CAS No. 259149-65-0. Pack Sizes: 25mg, 100mg. Molecular Formula: C16H13ClO4. US Biological Life Sciences. | Worldwide |
| 1,3-Benzothiazol-2-ylacetonitrile | 1,3-Benzothiazol-2-ylacetonitrile is an intermediate used to prepare substituted benzothiazoleacetonitr i les and benzothiazolyl aminopyridinecarbonitr i les as anticancer agents. It is also used in the synthesis of pyrrolo [3, 2-b] pyrazinedicarbonitri les as protein kinase inhibitors with antiproliferative activity in human cancer cell lines. Group: Biochemicals. Grades: Highly Purified. CAS No. 56278-50-3. Pack Sizes: 1g, 5g. Molecular Formula: C9H6N2S, Molecular Weight: 174.22. US Biological Life Sciences. | Worldwide |
| 1,3-Dichloro-2-methyl-benzene | 1,3-Dichloro-2-methyl-benzene is a useful synthetic intermediate. It can be used to prepare aryloxymethyl-substituted dibenzo[b,f]azocines as potential protein kinase A inhibitors. It can also be used to prepare dimethylglycine sulfonamides as potential bradykinin hB2 receptor antagonists. Isoconazole Impurity 10. Group: Biochemicals. Grades: Highly Purified. CAS No. 118-69-4. Pack Sizes: 10g, 25g. Molecular Formula: C7H6Cl2, Molecular Weight: 161.03. US Biological Life Sciences. | Worldwide |
| 1- (3-Nitrophenyl) methanesulfonamide | 1- (3-Nitrophenyl) methanesulfonamide is a useful synthetic intermediate. It can be used to synthesize synthesize disubstituted pyridine derivatives as inhibitors of the protein cyclin-dependent kinase (CDK). Group: Biochemicals. Grades: Highly Purified. CAS No. 110654-66-5. Pack Sizes: 500mg, 5g. Molecular Formula: C7H8N2O4S, Molecular Weight: 216.21. US Biological Life Sciences. | Worldwide |
| 1-(4-Chloro-3-(trifluoromethyl)phenyl)urea | An impurity of Sorafenib. Sorafenib is a small inhibitor of several tyrosine protein kinases, such as VEGFR, PDGFR and Raf family kinases, for the treatment of primary kidney cancer, advanced primary liver cancer and radioactive iodine resistant advanced thyroid carcinoma. Synonyms: N-[4-Chloro-3-(trifluoromethyl)phenyl]urea; Sorafenib Impurity 1; Sorafenib related compound 1; 1-[3-(Trifluoromethyl)-4-chlorophenyl]urea; Sorafenib Related Compound 9. Grades: > 95%. CAS No. 343247-69-8. Molecular formula: C8H6ClF3N2O. Mole weight: 238.59. | |
| 1,4-Diaminoanthraquinone | An anthraquinone derivative that is a potent and selective protein kinase CK1 delta inhibitor. Studies suggest that it has potential solar cell applications. Used in studies as a potential competitive non-peptidic inhibitor of HIV-1 proteinase. Group: Biochemicals. Alternative Names: 1,4-Diamino-9,10-anthraquinone; Acetate Red Violet R; Acetoquinone Light Heliotrope NL; Acetylon Fast Red Violet R; Akasperse Violet 3R; Amacel Heliotrope R; Cibacet Violet 2R; C.I. 61100; NSC 63807; NSC 7833; Krisolamine; Violet 14447. Grades: Highly Purified. CAS No. 128-95-0. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| 1,4-Dichlorophthalazine | 1,4-Dichlorophthalazine, is an intermediate in the synthesis of phthalazinone derivatives, acting as protein kinases inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 4752-10-7. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C8H4Cl2N2, Molecular Weight: 199.04. US Biological Life Sciences. | Worldwide |
| 1-(5-Isoquinolinesulfonyl)-2-methyl-4-trityl-piperazine | A selective inhibitor of protein kinase C or cyclic-nucleotide-dependent protein kinases. Group: Biochemicals. Alternative Names: 5-[ (2-Methyl-4-trityl-1-piperazinyl) sulfonyl]isoquinoline. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 1-(5-Isoquinolinesulfonyl)-3-methylpiperazine, Dihydrochloride | A selective inhibitor of protein kinase C or cyclic-nucleotide-dependent protein kinases. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 1-(5-Isoquinolinesulfonyl)-4-tert-butyloxycarbonyl-2-methylpiperazine | 1-(5-Isoquinolinesulfonyl)-4-tert-butyloxycarbonyl-2-methylpiperazine is a protected 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine (I885000), a selective inhibitor of protein kinase C or cyclic-nucleotide-dependent protein kinases. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 1-Acetamido-4-cyano-3-methylisoquinoline (1-Acetamido-3-methyl-4-cyanosoquinoline) | A selective inhibitor of cyclic AMP-dependent protein kinase (PKA). Group: Biochemicals. Alternative Names: 1-Acetamido-3-methyl-4-cyanosoquinoline. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 1-Benzyl-4-methylpiperidin-3-one | 1-Benzyl-4-methylpiperidin-3-one is an intermediate used to prepare pyrrolo[2,3-d]pyrimidine compds. as inhibitors of protein kinases. Group: Biochemicals. Grades: Highly Purified. CAS No. 32018-96-5. Pack Sizes: 1g, 2.5g. Molecular Formula: C13H17NO, Molecular Weight: 203.28. US Biological Life Sciences. | Worldwide |
| [1- (Ethylamino) cyclohexyl]methanol | [1- (Ethylamino) cyclohexyl]methanol is used in the synthetic preparation of imidazopyrazines as protein kinase inhibitors useful in the treatment of kinase-mediated diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 852108-26-0. Pack Sizes: 250mg, 1g. Molecular Formula: C9H19NO, Molecular Weight: 157.25. US Biological Life Sciences. | Worldwide |
| 1-Methoxy-2-propanol | 1-Methoxy-2-propanol is used as a reagent in the synthesis of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors. Also used as a reagent in the synthesis of Metolachlor (M338700); a selective pre-emergence herbicide. Group: Biochemicals. Grades: Highly Purified. CAS No. 107-98-2. Pack Sizes: 1g, 10g. Molecular Formula: C4H10O2, Molecular Weight: 90.12. US Biological Life Sciences. | Worldwide |
| 1-Naphthyl PP1 | 1-Naphthyl PP1 (1-NA-PP 1) is a selective inhibitor of src family kinases and Protein Kinase D. 1-Naphthyl PP1 inhibits v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC 50 s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 1-NA-PP 1. CAS No. 221243-82-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13941. | |
| 1-O-Hexadecyl-2-O-methylglycerol | 1-O-Hexadecyl-2-O-methylglycerol is an inhibitor of protein kinase C. It inhibits the respiratory burst in human neutrophils. Group: Biochemicals. Grades: Highly Purified. CAS No. 84337-41-7. Pack Sizes: 25mg, 50mg. Molecular Formula: C20H42O3, Molecular Weight: 330.55. US Biological Life Sciences. | Worldwide |
| 1-O-Hexadecyl-2-O-methylglycerol-d5 | 1-O-Hexadecyl-2-O-methylglycerol-d5 is labelled 1-O-Hexadecyl-2-O-methylglycerol (H290985) which is an inhibitor of protein kinase C. It inhibits the respiratory burst in human neutrophils. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C20H37D5O3, Molecular Weight: 335.58. US Biological Life Sciences. | Worldwide |
| (20S)-Protopanaxadiol | (20S)-Protopanaxadiol is used in the treatment of cerebral ischemic injury and the reversal of oxidative stress. A novel class of AMP-activated protein kinase (AMPK) inhibitors affecting glucose and lipid metabolism. Group: Biochemicals. Grades: Highly Purified. CAS No. 30636-90-9. Pack Sizes: 5mg, 50 mg. Molecular Formula: C30H52O3. US Biological Life Sciences. | Worldwide |
| 2- (1-Naphthalenylcarbonyl) propanedinitrile | Used in the preparation of inhibitors that target calcium-dependent protein kinases in C. parvum and T. gondii parazites. Group: Biochemicals. Grades: Highly Purified. CAS No. 1236038-48-4. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 2-(1-Piperidino)aniline | 2-(1-Piperidino)aniline is used to prepare oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B. It is also used to synthesize benzimidazole derivatives as AMP-activated protein kinase activators. Group: Biochemicals. Grades: Highly Purified. CAS No. 39643-31-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C11H16N2. US Biological Life Sciences. | Worldwide |
| 2-(2-Chloropyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one | 2-(2-Chloropyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one is used to prepare pyrrolopyridine Inhibitors of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MK-2). It is also used to synthesize heteroaryl-substituted pyrrolopyridinones and analogs as cdc7 kinase inhibitors and potential antitumor agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 724726-05-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C12H10ClN3O. US Biological Life Sciences. | Worldwide |
| (2, 2-Difluorocyclopropyl) methylamine | (2, 2-Difluorocyclopropyl) methylamine is a difluorinated-derivative of Cyclopropylmethylamine (C988695) and is used as a reagent in the synthesis of pyrrolidine derivatives as alternative pathway modulators for the treatment of ophthalmic and other diseases. (2, 2-Difluorocyclopropyl) methylamine is also used as the starting material in the synthesis of dihydrodiazepines as protein kinases inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 847926-81-2. Pack Sizes: 100mg, 1g. Molecular Formula: C4H7F2N, Molecular Weight: 107.1. US Biological Life Sciences. | Worldwide |
| 2-[3-(Benzyloxy)phenyl]-2-methylpropionitrile | Reagent used in the preparation of BACE inhibitors and protein kinase C ligands. Group: Biochemicals. Alternative Names: α , α -dimethyl-3- (phenylmethoxy) benzeneacetonitrile. Grades: Highly Purified. CAS No. 70120-08-0. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 2,3-Dichloro-6-nitrobenzaldehyde | 2,3-Dichloro-6-nitrobenzaldehyde is a reactant used in the synthesis of Staurosporinone (K000510) analogues. Staurosporinone acts as a protein kinase C inhibitor of microbial origin. Group: Biochemicals. Grades: Highly Purified. CAS No. 75618-41-6. Pack Sizes: 2.5g, 5g. Molecular Formula: C7H3Cl2NO3, Molecular Weight: 220.01. US Biological Life Sciences. | Worldwide |
| 2-[4-[(1-(1,3-Benzodioxol-5-yl)-2-phenyl-1-buten-1-yl]phenoxy]-N,N-dimethylethanamine Hydrochloride. (E/Z Mixture) | 2-[4-[(1-(1,3-Benzodioxol-5-yl)-2-phenyl-1-buten-1-yl]phenoxy]-N,N-dimethylethanamine Hydrochloride is a metabolite of Tamoxifen (T006000), a selective estrogen response modifier, protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 25mg. Molecular Formula: C26H28ClNO3. US Biological Life Sciences. | Worldwide |
| 2-[4-(1,2-Diphenyl-1-propenyl)phenoxy]-N,N-dimethylethanamine-d6 (E/Z Mixture) | 2-[4-(1,2-Diphenyl-1-propenyl)phenoxy]-N,N-dimethylethanamine-d6 is the isotope labelled analog of 2-[4-(1,2-Diphenyl-1-propenyl)phenoxy]-N,N-dimethylethanamine (D492270); an impurity of Tamoxifen (T006000) which is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C25H21D6NO, Molecular Weight: 363.52. US Biological Life Sciences. | Worldwide |
| 2-[4-(1,2-Diphenyl-1-propenyl)phenoxy]-N,N-dimethylethanamine (E/Z Mixture) | 2-[4-(1,2-Diphenyl-1-propenyl)phenoxy]-N,N-dimethylethanamine is an impurity of Tamoxifen (T006000); a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. CAS No. 197251-11-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C25H27NO, Molecular Weight: 357.49. US Biological Life Sciences. | Worldwide |
| 2- (4- ( (4- (2- (Dimethylamino) ethoxy) phenyl) (phenyl) methyl) phenyl) -4, 4-dimethyloxazolidin-2-ol | 2- (4- ( (4- (2- (Dimethylamino) ethoxy) phenyl) (phenyl) methyl) phenyl) -4, 4-dimethyloxazolidin-2-ol is an intermediate in the synthesis of Tamoxifen (T006000), a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C28H34N2O3. US Biological Life Sciences. | Worldwide |
| 2- (4- ( (4- (4, 4-Dimethyl-4, 5-dihydrooxazol-2-yl) phenyl) (phenyl) methyl) phenoxy) -N, N-dimethylethanamine | 2- (4- ( (4- (4, 4-Dimethyl-4, 5-dihydrooxazol-2-yl) phenyl) (phenyl) methyl) phenoxy) -N, N-dimethylethanamine is an intermediate in the synthesis of Tamoxifen (T006000), a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C28H32N2O2. US Biological Life Sciences. | Worldwide |
| (2, 6-Dichlorophenyl) methanamine | (2, 6-Dichlorophenyl) methanamine was one of the reactants used in making a library of highly selective and potent G protein-coupled receptor kinase 2 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 6575-27-5. Pack Sizes: 250mg, 1g. Molecular Formula: C7H7Cl2N, Molecular Weight: 176.04. US Biological Life Sciences. | Worldwide |
| 2-Acetamido-5-chloroisonicotinic Acid | 2-Acetamido-5-chloroisonicotinic Acid is a chemical reagent used in the synthesis of p38a protein kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 944390-08-3. Pack Sizes: 1g, 5g. Molecular Formula: C8H7ClN2O3, Molecular Weight: 214.61. US Biological Life Sciences. | Worldwide |
| 2-Acetylamino-4-methylpyridine | 2-Acetylamino-4-methylpyridine is a chemical reagent used in the synthesis of potent inhibitors of Eimeria tenalla cGMP-dependant protein kinase as antiparasitic agents. Also used in the 1-pot synthesis of difluoromethyl-2-pyridone derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 5327-32-2. Pack Sizes: 5g, 25g. Molecular Formula: C8H10N2O, Molecular Weight: 150.18. US Biological Life Sciences. | Worldwide |
| 2-Amino-3-carboethoxy-4-(3-methylphenyl)thiophene | 2-Amino-3-carboethoxy-4-(3-methylphenyl)thiophene is used in the synthesis of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 255713-71-4. Pack Sizes: 250mg, 2.5g. Molecular Formula: C14H15NO2S, Molecular Weight: 261.339999999999. US Biological Life Sciences. | Worldwide |
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