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Prucalopride is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pK i s of 8.6 and 8.1 for human 5-HT4a/4b receptors , respectively. Prucalopride improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 179474-81-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14151.
Prucalopride
Prucalopride is a potent and selective 5-HT4 receptor agonist. Prucalopride is a gastroprokinetic drug with the brand name Resolor, developed for the treatment of constipation and irritable bowel syndrome. Studies indicates that it is promisingly to be a candidate therapy of Alzheimer's disease and chronic intestinal pseudo-obstruction. Uses: Gastroprokinetic drug. Synonyms: Resolor; 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide. Grades: 99%. CAS No. 179474-81-8. Molecular formula: C18H26ClN3O3. Mole weight: 367.87.
Prucalopride Dimer Impurity
An impurity of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Grades: > 95%. Molecular formula: C26H30Cl2N4O5. Mole weight: 549.46.
Prucalopride Hydroxy Impurity
An impurity of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Grades: > 95%. Molecular formula: C18H26ClN3O4. Mole weight: 383.88.
Prucalopride Impurity 1
An impurity of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Grades: > 95%. Molecular formula: C18H24ClN3O3. Mole weight: 365.86.
Prucalopride Impurity 1
Prucalopride Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2636673-48-6. Molecular Formula: C18H26ClN3O4. Mole Weight: 383.87. Catalog: APB2636673486.
Prucalopride Impurity 10
An impurity of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Grades: > 95%. Molecular formula: C19H26ClN3O4. Mole weight: 395.89.
Prucalopride Impurity 3
An impurity of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Grades: > 95%. Molecular formula: C30H46ClN3O13. Mole weight: 692.17.
Prucalopride Impurity 4
An impurity of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Grades: > 95%. CAS No. 1599434-55-5. Molecular formula: C17H24ClN3O3. Mole weight: 353.85.
Prucalopride Impurity 4
Prucalopride Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 179474-85-2. Molecular Formula: C22H32ClN3O7. Mole Weight: 485.96. Catalog: APB179474852.
Prucalopride Impurity 5
An impurity of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Grades: > 95%. Molecular formula: C20H28ClN3O4. Mole weight: 409.92.
Prucalopride Impurity 6
An impurity of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Synonyms: Prucalopride Impurity 6; 1608459-56-8; PRUCALOPRIDESUCCINATE IMPURITY 13; 4-amino-N-[1-(3-methoxypropyl)piperidin-4-yl]-2,3-dihydro-1-benzofuran-7-carboxamide; BCP33675; PRUCALOPRIDESUCCINATEIMPURITY13; 4-Amino-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran -7-carboxamide. Grades: > 95%. CAS No. 1608459-56-8. Molecular formula: C18H27N3O3. Mole weight: 333.43.
Prucalopride Impurity 7
An impurity of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Grades: > 95%. Molecular formula: C20H29N3O4. Mole weight: 375.47.
Prucalopride Impurity 8
An impurity of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Grades: > 95%. Molecular formula: C12H12ClNO4. Mole weight: 269.69.
Prucalopride Impurity 9
An impurity of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Grades: > 95%. Molecular formula: C14H12ClN3O3. Mole weight: 305.72.
Prucalopride N-Oxide
A metabolite of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Synonyms: N-Oxo Prucalopride; 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-1-oxido-4-piperidinyl]-7-benzofurancarboxamide. Grades: > 95%. CAS No. 1900715-98-1. Molecular formula: C18H26ClN3O4. Mole weight: 383.88.
Prucalopride succinate
Prucalopride succinate is an orally active, selective and specific 5-HT 4 receptor agonist (high affinity), with pK i s of 8.6 and 8.1 for human 5-HT4a/4b receptors , respectively. Prucalopride succinate improves intestinal motility by promoting regeneration of the intestinal nervous system in rats. Prucalopride succinate also shows anticancer activity by blocking of the PI3K/AKT/mTor signaling pathway. Prucalopride succinate can be used in studies of chronic constipation, pseudo-intestinal obstruction and cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-108512. CAS No. 179474-85-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12694.
Prucalopride Succinate
A derivative of Prucalopride. Prucalopride is a selective, high affinity 5-HT4 receptor agonist. It has been tested for the treatment of chronic intestinal pseudo-obstruction. Synonyms: 4-amino-5-chloro-N-(1-(3-methoxypropyl)piperidin-4-yl)-2,3-dihydrobenzofuran-7-carboxamide succinate; R-108512; R 108512; R108512; Prucalopride Succinate; Resolor; Resotran. Grades: > 95%. CAS No. 179474-85-2. Molecular formula: C18H26ClN3O3 C4H6O4. Mole weight: 458.97.
Prucalopride Succinate
Prucalopride is a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe. Group: Biochemicals. Alternative Names: 4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide Butanedioic Acid; R 108512; Resolor. Grades: Highly Purified. CAS No. 179474-85-2. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Prucalopride Succinate-13CD3
Prucalopride Succinate-13CD3 is the labeled analogue of Prucalopride Succinate (P838950). Prucalopride is a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C2113CH29D3ClN3O7, Molecular Weight: 489.97. US Biological Life Sciences.
Worldwide
1-(3-Methoxypropyl)-4-piperidinamine
1-(3-Methoxypropyl)-4-piperidinamine is a useful synthetic intermediate in the synthesis of Prucalopride Succinate (P838950); a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe. Group: Biochemicals. Grades: Highly Purified. CAS No. 179474-79-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H20N2O, Molecular Weight: 172.27. US Biological Life Sciences.