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| Product | Description | |
|---|---|---|
| PSB 0777 ammonium salt | PSB 0777 ammonium salt. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| PSB 0777 ammonium salt | PSB 0777 is a potent adenosine A2A receptor full agonist (Ki = 44.4 nM for rat brain striatal A2A receptors), with subtype selectivity for A2A receptors over A1, A2B and A3 receptors (Ki ≥ 10 000 nM for rat A1, human A2B and human A3 receptors). The beneficial effects of PSB-0777 on inflammatory parameters were prevented by the pharmacological blockade of A2A receptors. No adverse cardiovascular events were observed upon PSB-0777 administration. The novel A2A receptor agonist PSB-0777 could represent the base for the development of innovative pharmacological entities able to act in an event-specific and site-specific manner. Synonyms: PSB 0777 ammonium salt; PSB0777 ammonium salt; PSB-0777 ammonium salt; 4-[2-[(6-Amino-9-b-D-ribofuranosyl-9H-purin-2-yl)thio]ethyl]benzenesulfonic acid ammonium salt. Grades: ≥98% by HPLC. CAS No. 2122196-16-9. Molecular formula: C18H20N5O7S2.NH4. Mole weight: 500.55. |  |
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