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| Product | Description | |
|---|---|---|
| Purvalanol B | ?97% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. |  |
| Purvalanol B | Purvalanol B (NG 95) is a potent, selective, reversible and ATP-competitive inhibitor CDK, with IC50s of 6 nM, 6 nM, 9 nM, 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively. Purvalanol B shows selectivity for CDK over a range of other protein kinases (IC50>1000 nM). Purvalanol B inhibits the growth a chloroquine-resistant strain of P. falciparum[1][1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NG 95. CAS No. 212844-54-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-18299. |  |
| Purvalanol A, Free Base, 99+% | Purvalanol A is a cell-permeable, potent, and selective cyclin-dependent kinase (CDK) inhibitor. It inhibited CDK kinases with IC50 values of 4 nM for CDC2/cyclin B, 70 nM for CDK2/cyclin A, 35 nM for CDK2/cyclin E, 75 nM for CDK5/p35, and 850 nM for CDK4/cyclin D1. Gray N.S., et al. “Exploiting chemical libraries, structure and genomics in the search for kinase inhibitors.” Science 281: 533-538 (1998). Group: Biochemicals. Grades: Highly Purified. CAS No. 212844-53-6. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences. |  Worldwide |
| Purvalanol A | Purvalanol A is a potent CDK inhibitor, which inhibits cdc2-cyclin B, cdk2-cyclin A, cdk2-cyclin E, cdk4-cyclin D1, and cdk5-p35 with IC50s of 4, 70, 35, 850, 75 nM, resepctively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NG-60. CAS No. 212844-53-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18299A. | |
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