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| Product | Description | |
|---|---|---|
| PYR-41 | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. |  |
| PYR-41 | PYR-41 is a selective and cell permeable inhibitor of ubiquitin-activating enzyme E1 with an IC 50 of < 10 μM, with little activity at E2 and E3. Uses: Scientific research. Group: Signaling pathways. CAS No. 418805-02-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13296. |  |
| PYR-41 | PYR-41 is a ubiquitin-activating enzyme inhibitor (UBE1 inhibitor). PYR-41 blocks ubiquitination reactions but paradoxically leads to the accumulation of high MW ubiquitinated proteins. PYR-41 also mediated cross-linking of specific protein kinases (Bcr-Abl, Jak2) to inhibit their signaling activity. PYR-41 has demonstrated anti-tumor activity in animal studies, partially selective protein cross-linking may represent an alternate approach to affect signal transduction modules and ubiquitin cycle-regulatory proteins for cancer therapy. Synonyms: PYR-41; PYR 41; PYR41. Grades: 0.98. CAS No. 418805-02-4. Molecular formula: C17H13N3O7. Mole weight: 371.305. |  |
| Ubiquitin E1 Inhibitor, PYR-41 | The Ubiquitin E1 Inhibitor, PYR-41 controls the biological activity of Ubiquitin E1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications. Group: Fluorescence/luminescence spectroscopy. | |
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