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Crosslinking agent in immobilization of thrombogenesis-inhibiting enzymes on polymeric carriers. Targeted delivery of a triplex-forming oligonucleotide to hepatic stellate cells by complexes with phosphated bovine serum albumin for treatment of liver fibrosis. Group: Biochemicals. Alternative Names: 2-Carboxyethyl 2-Pyridyl Disulfide. Grades: Highly Purified. CAS No. 68617-64-1. Pack Sizes: 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
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3-(2-Pyridyldithio)propanoic Acid
3-(2-Pyridyldithio)propanoic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 68617-64-1. Pack Sizes: 100 mg; 500 mg. Product ID: HY-130157.
3- (2-Pyridyldithio) propanoic acid hydrazide
3- (2-Pyridyldithio) propanoic acid hydrazide. Group: Biochemicals. Alternative Names: PDTPA-hydrazide. Grades: Highly Purified. CAS No. 115616-51-8. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C8H11N3OS2. US Biological Life Sciences.
A heterobifunctional cross-linker. Group: Biochemicals. Alternative Names: SPDP. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
A sulfhydryl reactive biotinylaton reagent. Group: Biochemicals. Alternative Names: PDTE-BIOTIN. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Ideal for biotinylating antibody or protein for use in protein detection, purification or immobilization. Group: Biochemicals. Alternative Names: N-[6-(Biotinamido)hexyl]-3-(2-pyridyldithio)-propionamide, Biotin-HPDP, Pyridyldithiol-biotin, Pyridyldisulfide-biotin. Grades: Purified. CAS No. 129179-83-5. Pack Sizes: 50mg. US Biological Life Sciences.
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PDP-Doxorubicin Liposome (PEGylated)
This formulation is Doxorubicin Liposome (PEGylated) with the pyridyldithiopropionate (PDP) group. The liposome containing PDP lipids are used to conjugate proteins, antibodies and other molecules containing the reactive moiety. The PDP group contains disulfide, which can react with sulfhydryl or thiolated proteins/antibodies. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes.
SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups. Uses: A heterobifunctional cross-linker. Synonyms: N-Succinimidyl 3-(2-Pyridyldithio)Propionate; UNII-2OHG8V08NL; SPDP NHS Ester; 3-(2-Pyridyldithio)Propionic Acid N-Hydroxysuccinimide Ester. Grades: ≥ 97% (HPLC). CAS No. 68181-17-9. Molecular formula: C12H12N2O4S2. Mole weight: 312.37.
SPDP
SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SPDP Crosslinker; Py-ds-Prp-OSu. CAS No. 68181-17-9. Pack Sizes: 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-100216.
SPDP Crosslinker
SPDP contains a dithiopyridyl group which is reactive towards cysteines (-SH groups) and an NHS group, which is useful when targeting primary amines (-NH2 groups). SPDP releases a byproduct, pyridine-2-thione after reacting with free sulfhydryl groups. By measuring the release of this byproduct at 343nm, the reaction can be easily followed. Contains a disulfide linkage in its spacer arm with a length of 6.8. Group: Biochemicals. Alternative Names: N-succinimidyl-3- (2-pyridyldithio) propionate; 3- (2-Pyridyldithio) propionic acid N-hydroxysuccinimide ester; 3- (2-Pyridyldithio) propionic acid NHS ester. Grades: Highly Purified. CAS No. 68181-17-9. Pack Sizes: 50mg, 250mg. US Biological Life Sciences.
Worldwide
SPP
SPP (N-succinimidyl 4-(2-pyridyldithio) pentanoate) is a cleavable disulfide linker, can be used to form cytotoxic compound- linker conjugate [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-succinimidyl 4-(2-pyridyldithio) pentanoate. CAS No. 341498-08-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128926.
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