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1-[3-Chloro-2,3-dideoxy-5-O-(triphenylmethyl)-β-D-threo-pentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione is an important pharmaceutical intermediate. It has shown potential in framing compounds to combat diseases like HIV and Hepatitis. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[3-chloro-2,3-dideoxy-5-O-(triphenylmethyl)-β-D-threo-pentofuranosyl]-5-methyl-; 3-chloro-1,2,3-trideoxy-1-thymin-1-yl-5-O-trityl-beta-D-threo-pentofuranose; 1-((2R,4R,5R)-4-chloro-5-((trityloxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione. Grade: ≥95%. CAS No. 34627-64-0. Molecular formula: C29H27ClN2O4. Mole weight: 503.00.
1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-2,4(1H,3H)-pyrimidinedione is a vital compound extensively utilized in the field of biomedicine. This product acts as a key reagent in the synthesis of modified nucleotides for research purposes. It is commonly employed in DNA and RNA synthesis, particularly in the development of oligonucleotides for therapeutic interventions targeting various diseases, such as cancer and viral infections. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-; 5-O-(4,4'-Dimethoxytrityl)-2-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1,3-dideoxy-1-uracil-1-yl-beta-D-threo-pentofuranose; (2R,3S,5S)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 3'-ara-dU Phosphoramidite; 5'-O-DMTr-3'-deoxyuridine ara-2'-phosphoramidite. Grade: ≥95%. CAS No. 161503-98-6. Molecular formula: C39H47N4O8P. Mole weight: 730.79.
1-(3-amino-3-deoxy-β-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-Pyrimidinedione, a powerful antiviral medication, effectively combats viral infections such as HIV and hepatitis B. Its mechanism of action interferes with the virus's replication cycle, ultimately reducing symptom severity. Synonyms: 1-(3-Amino-3-deoxy-β-D-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione. CAS No. 97762-01-1. Molecular formula: C10H15N3O5. Mole weight: 257.24.
The biochemical 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2,3-dideoxy-2-fluoro-3-[[(4-methoxyphenyl)diphenylmethyl]amino]-β-D-arabinofuranosyl]-5-methyl-, is well known in the biomedical realm due to its anticancer effects, serving as a therapeutic agent for acute myeloid leukemia, chronic lymphocytic leukemia, and non-Hodgkin's lymphoma by impeding DNA synthesis and obstructing the propagation and dissemination of malignant cancerous cells, thereby proving to be an indispensable asset. Synonyms: 2-cyanoethyl (((2S,3R,4R,5R)-4-fluoro-3-(((4-methoxyphenyl)diphenylmethyl)amino)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite. CAS No. 329773-25-3. Molecular formula: C39H47FN5O6P. Mole weight: 731.79.
2,?4(1H,?3H)?-?Pyrimidinedione-?2-?13C
2,?4(1H,?3H)?-?Pyrimidinedione-?2-?13C is a labeled analog of Uracil (U801000). 2,?4(1H,?3H)?-?Pyrimidinedione-?2-?13C is used to identify dihydropyrimidine dehydrogenase deficiency by breath test. Group: Biochemicals. Grades: Highly Purified. CAS No. 35803-45-3. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C313CH4N2O2, Molecular Weight: 113.08. US Biological Life Sciences.
2,4(1H,3H)-Pyrimidinedione,6-(dimethylamino)-5-methyl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-METHYL-6-DIMETHYLAMINOURACIL;6-(DIMETHYLAMINO)-5-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE. Product Category: Heterocyclic Organic Compound. CAS No. 70629-11-7. Molecular formula: C7H11N3O2. Mole weight: 169.18. Purity: 0.96. IUPACName: 6-(dimethylamino)-5-methyl-1H-pyrimidine-2,4-dione. Canonical SMILES: CC1=C(NC(=O)NC1=O)N(C)C. Density: 1.24g/cm³. Product ID: ACM70629117. Alfa Chemistry ISO 9001:2015 Certified.
An impurity of Elagolix sodium, a medication indicated for the treatment of moderate to severe pain associated with endometriosis. Grade: 95%. CAS No. 2486454-65-1. Molecular formula: C28H22F5N3O4. Mole weight: 559.5.
2-Amino-5-ureido-4,6-pyrimidinedione
2-Amino-5-ureido-4,6-pyrimidinedione. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
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2-Methyl-5-nitro-4,6(1H,5H)-pyrimidinedione
2-Methyl-5-nitro-4,6(1H,5H)-pyrimidinedione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Methyl-5-Nitro-4,6(1H,5H)-Pyrimidinedione;4,6(1H,5H)-Pyrimidinedione,2-methyl-5-nitro-. Product Category: Heterocyclic Organic Compound. CAS No. 680881-02-1. Molecular formula: C5H5N3O4. Mole weight: 171.1109. Purity: 0.96. IUPACName: 2-methyl-5-nitro-1H-pyrimidine-4,6-dione. Canonical SMILES: CC1=NC(=O)C(C(=O)N1)[N+](=O)[O-]. Density: 1.84g/cm³. Product ID: ACM680881021. Alfa Chemistry ISO 9001:2015 Certified.
2-Methylthio-4,6-pyrimidinedione
2-Methylthio-4,6-pyrimidinedione. Uses: Designed for use in research and industrial production. Product Category: Pyrimidines. Appearance: White to Off White Powder. CAS No. 1979-98-2. Molecular formula: C5H6N2O2S. Mole weight: 158.18. Purity: 0.97. Product ID: ACM1979982. Alfa Chemistry ISO 9001:2015 Certified.
(2R-cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione (Lamivudine EP Impurity J) is an impurity of Lamivudine (L172500). (2R-cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione is also being further studied to determine its potential as an anti-HIV agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 145986-07-8. Pack Sizes: 25mg, 100mg. Molecular Formula: C8H10N2O4S. US Biological Life Sciences.
5-Fluoro-3'-thia-2',3'-dideoxyuridine is an impurity of ent-Emtricitabine (E525005), a reverse transcriptase inhibitor and an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. In addition, ent-Emtricitabine (E525005) is a nucleoside analog structurally related to Lamivudine (L172500). Group: Biochemicals. Grades: Highly Purified. CAS No. 145281-92-1. Pack Sizes: 1mg, 5mg. Molecular Formula: C8H9FN2O4S, Molecular Weight: 248.23. US Biological Life Sciences.
An impurity of Elagolix sodium, a medication indicated for the treatment of moderate to severe pain associated with endometriosis. Grade: 95%. CAS No. 2354391-45-8. Molecular formula: C13H10F4N2O2. Mole weight: 302.22.
3-(3-Azido-2,3-dideoxy- β-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione is an impurity of Zidovudine (A825000). Zidovudine is an antiviral agent used in the clinical treatment of HIV infections. Group: Biochemicals. Grades: Highly Purified. CAS No. 123606-70-2. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C10H13N5O4. US Biological Life Sciences.
3-(3-Azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione is an impurity of Zidovudine. Zidovudine is an antiviral agent used in the clinical treatment of HIV infections. Grade: 98%. CAS No. 123606-70-2. Molecular formula: C10H13N5O4. Mole weight: 267.24.
4,6(1H,5H)-Pyrimidinedione(7ci,8ci,9ci)
4,6(1H,5H)-Pyrimidinedione(7ci,8ci,9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,6(1H,5H)-Pyrimidinedione (7CI,8CI,9CI). Product Category: Heterocyclic Organic Compound. CAS No. 25286-58-2. Molecular formula: C4H4N2O2. Mole weight: 112.08676. Product ID: ACM25286582. Alfa Chemistry ISO 9001:2015 Certified.
5-Bromo-2,4-pyrimidinedione-13C,15N2
5-Bromo-2,4-pyrimidinedione-13C,15N2. Group: Biochemicals. Alternative Names: 5-Bromouracil-13C,15N2; Bromouracil-13C,15N2; NSC 19940-13C,15N2; 5-Bromo-2,4(1H,3H)-pyrimidinedione-13C,15N2; 5-Bromo-2,4-dihydroxypyrimidine-13C,15N2. Grades: Highly Purified. CAS No. 181517-13-5. Pack Sizes: 5mg. Molecular Formula: C4H3BrN2O2, Molecular Weight: 190.98. US Biological Life Sciences.
A major chemical mutagen. Incorporates into DNA, altering base-pair sequencing by replacing thymine. Group: Biochemicals. Alternative Names: 5-Bromo-2,4-(1H,3H)-pyrimidinedione. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences.
One of the impurities of Tipiracil, which is a thymidine phosphorylase (TPase) inhibitor and has been found to be a potential drug candidate for metastatic colorectal cancer. Synonyms: Tipiracil Impurity C. Grade: ≥95%. CAS No. 2101241-71-6. Molecular formula: C9H12ClN3O3. Mole weight: 245.66.
5-Fluoro-1-(β-D-ribopyranosyl)-2,4(1H,3H)-pyrimidinedione is a remarkable compound, showcasing its antiviral properties. This concoction exerts a inhibitory efficacy against certain RNA virus strains. Its modus operandi lies in its adeptness at impeding viral replication through disruption of the intricate enhancement of viral genetic material. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-β-D-ribopyranosyl-; 5-fluoro-1-((2R,3R,4R,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grade: ≥95%. CAS No. 77180-80-4. Molecular formula: C9H11FN2O6. Mole weight: 262.19.
5-Nitro-6-(D-ribitylamino)-2,4(1H,3H)-pyrimidinedione is an intermediate in the synthesis of Lumazine fluorophore. Synonyms: 5-Nitro-6-[(ribo-2,3,4,5-tetrahydroxypentyl)amino]uracil; 1-Deoxy-1-[(2,6-Dihydroxy-5-nitro-4-pyrimidinyl)amino]ribitol; 1-Deoxy-1-[(1,2,3,6-tetrahydro-5-nitro-2,6-dioxo-4-pyrimidinyl)amino]-D-ribitol. CAS No. 52918-39-5. Molecular formula: C9H14N4O8. Mole weight: 306.23.
One of the impurities of Tipiracil, which is a thymidine phosphorylase (TPase) inhibitor and has been found to be a potential drug candidate for metastatic colorectal cancer. Synonyms: Tipiracil Impurity des Cl. Grade: ≥95%. CAS No. 2069937-25-1. Molecular formula: C9H12N4O2. Mole weight: 208.22.
Intermediate in the preparation of disubstituted Xanthine derivatives. Group: Biochemicals. Alternative Names: NSC 677538. Grades: Highly Purified. CAS No. 132716-86-0. Pack Sizes: 250mg. US Biological Life Sciences.
6-Amino-5-ethyl-5-(1-methylbutyl)-2,4(3H,5H)-pyrimidinedione-d5. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C11H14D5N3O2, Molecular Weight: 230.32. US Biological Life Sciences.
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6-Ethoxy-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione
6-Ethoxy-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-Ethoxy-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione;6-Ethoxy-1,3-dimethyluracil. Product Category: Heterocyclic Organic Compound. CAS No. 93787-99-6. Molecular formula: C8H12N2O3. Mole weight: 184.192480 [g/mol]. Purity: 0.96. IUPACName: 6-ethoxy-1,3-dimethylpyrimidine-2,4-dione. Canonical SMILES: CCOC1=CC(=O)N(C(=O)N1C)C. Density: 1.23g/cm³. Product ID: ACM93787996. Alfa Chemistry ISO 9001:2015 Certified.
6-Fluoro-1,5-dimethyl-2,4(1H,3H)-pyrimidinedione
6-Fluoro-1,5-dimethyl-2,4(1H,3H)-pyrimidinedione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-FLUORO-1,5-DIMETHYL-2,4(1H,3H)-PYRIMIDINEDIONE;1-METHYL-6-FLUOROTHYMINE. Product Category: Heterocyclic Organic Compound. CAS No. 112706-72-6. Molecular formula: C6H7FN2O2. Mole weight: 158.13. Purity: 0.96. IUPACName: 6-fluoro-1,5-dimethylpyrimidine-2,4-dione. Canonical SMILES: CC1=C(N(C(=O)NC1=O)C)F. Density: 1.35g/cm³. Product ID: ACM112706726. Alfa Chemistry ISO 9001:2015 Certified.
cis-1-[2-[(Acetyloxy)methyl]-1,3-oxathiolan-5-yl]-5-fluoro-2,4(1H,3H)-pyrimidinedione is an impurity of Lamivudine, a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has also been used for treatment of chronic hepatitis B. CAS No. 144963-94-0. Molecular formula: C10H11FN2O5S. Mole weight: 290.27.
An antiviral nucleoside analog, also an impurity found in emtricitabine. Synonyms: Emtricitabine 5-fluorouracil analog; (2R-cis)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione. Grade: 98%. CAS No. 145986-11-4. Molecular formula: C8H9FN2O4S. Mole weight: 248.23.
Antiviral nucleoside analog, Inhibition of human immunodeficiency and hepatitis B viruses. Group: Biochemicals. Alternative Names: (2R-cis)-5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)-pyrimidinedione-13C,15N2. Grades: Highly Purified. CAS No. 1217728-33-0. Pack Sizes: 1mg. US Biological Life Sciences.
Used as an antineoplastic. Group: Biochemicals. Alternative Names: 5-Fluoro-1-(tetrahydro-2-fuanyl)-2,4-(1H,3H)-pyrimidinedione, Citofur, Exonal, Fental. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
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[1'-13C]Uridine
[1'-13C]Uridine. Group: Biochemicals. Alternative Names: 1- β-D-Ribofuranosyluracil[1'-13C]; 1- β-D-Ribofuranosyluracil[1'-13C]; 1- β-D-Ribofuranosyl-2,4(1H,3H)-pyrimidinedione[1'-13C]; NSC 20256[1'-13C]; β-Uridine[1'-13C]. Grades: Highly Purified. CAS No. 201996-62-5. Pack Sizes: 1mg. Molecular Formula: C813CH12N2O6, Molecular Weight: 245.2. US Biological Life Sciences.
1-((1R,3R,4R,6S,7S)-7-hydroxy-1-(hydroxymethyl)-6-methyl-2,5-dioxabicyclo[2.2.1]heptan-3-yl)-5-methylpyrimidine-2,4(1H,3H)-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2'-o,4'-C-((1S)-Ethane-1,1-diyl)beta-D-ribose 5-methyl uridine; 1-(2,5-Anhydro-6-deoxy-4-C-(hydroxymethyl)-alpha-L-mannofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione. Product Category: Nucleosides. CAS No. 1197032-96-4. Molecular formula: C12H16N2O6. Mole weight: 284.27. Purity: 0.98. IUPACName: 1-[(1R,3R,4R,6S,7S)-7-hydroxy-1-(hydroxymethyl)-6-methyl-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methylpyrimidine-2,4-dione. Product ID: PR1197032964. Alfa Chemistry ISO 9001:2015 Certified.
Intermediate in the preparation of Gemcitabine metabolites and degradation products. Synonyms: 1-(3,5-Di-O-benzoyl-2-deoxy-2,2-difluoro-L-erythro-pentofuranosyl)-2,4(1H,3H)-pyrimidinedione. Molecular formula: C23H18F2N2O7. Mole weight: 472.4.
1-(2'-Deoxy-2'-chloro-b-L-arabinofuranosyl)-thymine, also known as 2'-C-C-AraT, is a nucleoside analog utilized in biomedical research particularly in antiviral and anticancer therapy studies. It has demonstrated inhibitory effects against Hepatitis B viral replication. Synonyms: 1-(2'-Deoxy-2'-chloro-β-L-arabinofuranosyl)-thymine; 1-[(2S,3R,4S,5S)-3-chloro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 1-(2-Chloro-2-deoxy-β-L-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione. Molecular formula: C10H13ClN2O5. Mole weight: 276.67.
1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil is a nucleoside analogue useful in cancer treatment research. This nucleoside analogue selectively interacts with a thymidylate synthase, inhibiting DNA synthesis thereby disrupting tumor cell growth. Synonyms: 1-(3,5-Di-O-benzoyl-2-deoxy-2-fluoro-beta-L-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione; 2,4(1H,3H)-Pyrimidinedione, 1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-L-arabinofuranosyl)-; 3,5-di-O-benzoyl-1,2-dideoxy-2-fluoro-1-uracil-1-yl-beta-L-arabino-pentofuranose. CAS No. 1312300-53-0. Molecular formula: C23H19FN2O7. Mole weight: 454.40.
1-(2'-Deoxy-2'-fluoro-a-L-arabinofuranosyl)-thymine is a potent antiviral substance. It inhibits DNA replication by interacting with viral DNA, thus preventing viral transmission. It has potential application in the field of HIV and hepatitis B infection control. Synonyms: alpha-Clevudine; 1-[(2R,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; 1-(2-Deoxy-2-fluoro-α-L-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-α-L-arabinofuranosyl)-5-methyl-. Grade: 95%. CAS No. 1027764-72-2. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
It is a metabolite of FMAU. Synonyms: 2'-Deoxy-2'-fluoro-5-hydroxymethyl-arabinouridine; 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-(hydroxymethyl)-2,4(1H,3H)-pyrimidinedione; 1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(hydroxymethyl)pyrimidine-2,4-dione. Grade: ≥95%. CAS No. 94817-51-3. Molecular formula: C10H13FN2O6. Mole weight: 276.22.
1-(2-Deoxy-4-thio-α-D-erythro-pentofuranosyl)thymine is a remarkable nucleoside analog possessing potent antiviral and antitumor properties. This compound efficaciously hampers the progress of HIV-1 reverse transcriptase and DNA polymerases. Piercing through the intricacies, its structural resemblance to thymidine empowers it to impede DNA replication, thus holding paramount potential in mitigating viral replication and repressing malignant neoplasms. Synonyms: 1-(2-Deoxy-4-thio-alpha-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-[(2S,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl]-5-methyl-pyrimidine-2,4-dione. Grade: 95%. CAS No. 134111-35-6. Molecular formula: C10H14N2O4S. Mole weight: 258.30.
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine is a nucleoside analogue used in antiviral research. It's primarily used in research of antiretroviral therapies, specifically combating HIV due to its ability to inhibit reverse transcriptase, a key enzyme in HIV replication. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyl-b-D-arabinouridine; 1-{5-O-[Bis-(4-Methoxyphenyl)phenylmethyl]-2-deoxy-2-fluoro-D-arabinofuranosyl}-5-methyl-2,4(1H,3H)-pyrimidinedione; 5'-O-(dimethoxytrityl)-2'-β-fluorothymidine. Grade: ≥98% by HPLC. CAS No. 144822-48-0. Molecular formula: C31H31FN2O7. Mole weight: 562.59.
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-β-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is used in the solid-phase synthesis of modified oligonucleotides. The modifications enhance the stability and binding affinity of the oligonucleotides. These modified nucleotides are valuable in various applications, including the development of antisense oligonucleotides, siRNA, and other therapeutic nucleic acids, as well as in research settings where enhanced stability and specific interactions are required. Synonyms: 5'-O-dimethoxytrityl-2'-deoxy-2'-fluoroarabinothymidine-3'-[(2-cyanoethyl)-(N,N-diisopropropyl)]-Phosphoramidite; 2'-F-ANA-T-3'-CE-Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine-3'-CED-phosphoramidite; 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; 2'-Deoxy-2'-fluoro-5-Me-ara-U-3'-CED-phosphoramidite. Grade: 97%. CAS No. 208193-48-0. Molecular formula: C40H48FN4O8P. Mole weight: 762.82.
1-((2R,6S)-6-(Hydroxymethyl)morpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, a small molecule inhibitor, possesses remarkable potency against various cancer types. Its mechanism of action involves targeting proteins essential for cancer cell growth and replication, promoting tumor shrinkage and cell death. As demonstrated in lung, breast, colon, and ovarian cancer, it exhibits impressive antitumor activity, embodying a promising candidate for cancer therapy. Synonyms: Morpholino thymidine; 1-((2R,6S)-6-(hydroxymethyl)morpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-[(2R,6S)-6-(Hydroxymethyl)-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; YML1Y6H5HD; 1-[(2R,6S)-6-(hydroxymethyl)morpholin-2-yl]-5-methylpyrimidine-2,4-dione; 1-((2R,6S)-6-(Hydroxymethyl)-2-morpholinyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-(6-Hydroxymethyl-morpholin-2-yl)-5-methyl-1H-pyrimidine-2,4-dione; 2,4(1H,3H)-Pyrimidinedione, 1-((2R,6S)-6-(hydroxymethyl)-2-morpholinyl)-5-methyl-; UNII-YML1Y6H5HD; SCHEMBL24420143; CS-0100784; A897935. CAS No. 179073-10-0. Molecular formula: C10H15N3O4. Mole weight: 241.24.
1-((2R,6S)-6-(Hydroxymethyl)morpholin-2-yl)pyrimidine-2,4(1H,3H)-dione, a critically important pharmaceutical component, serves as a fundamental precursor in synthesizing a spectrum of lifesaving medications, crucially employed in combating ailments like cancer, inflammation, and viral infections across varied biological settings and therapeutic contexts. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[(2R,6S)-6-(hydroxymethyl)-2-morpholinyl]-; 1-[(2R,6S)-6-(Hydroxymethyl)-2-morpholinyl]-2,4(1H,3H)-pyrimidinedione; 2,4(1H,3H)-Pyrimidinedione, 1-[6-(hydroxymethyl)-2-morpholinyl]-, (2R-cis)-; U-morpholine CH2OH. Grade: 97%. CAS No. 109205-43-8. Molecular formula: C9H13N3O4. Mole weight: 227.22.
1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)-5-bromo-uracil is a specialized synthetic compound pivotal in the development of anti-viral drugs. It's used primarily in research to study its inhibitory effects on the replication of certain DNA viruses, contributing to potential treatments for viral infections. Synonyms: 5-Bromo-3',5'-bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine; ((2R,3R,4S,5R)-3-(Benzoyloxy)-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-2-yl)methyl benzoate; 5-Bromo-1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione. Grade: ≥95%. CAS No. 213136-12-0. Molecular formula: C23H18BrFN2O7. Mole weight: 533.30.
1,3-Bis(4-methoxybenzyl)-5-fluorouracil
An Intermediate for the synthesis of uracil derivatives. Group: Biochemicals. Alternative Names: 5-Fluoro-1,3-bis[(4-methoxyphenyl)methyl]-2,4(1H,3H)-pyrimidinedione. Grades: Highly Purified. CAS No. 897304-05-1. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
1,3-Dibenzyl-5-fluorouracil
1,3-Dibenzyl-5-fluorouracil. Group: Biochemicals. Alternative Names: 5-Fluoro-1,3-bis(phenylmethyl)-2,4(1H,3H)-pyrimidinedione, NSC408345. Grades: Highly Purified. CAS No. 75500-02-6. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
1,3-Di(benzyloxymethyl)-5-fluorouracil
1,3-Di(benzyloxymethyl)-5-fluorouracil. Group: Biochemicals. Alternative Names: 5-Fluoro-1, 3-bis[ (phenylmethoxy)methyl]-2, 4 (1H, 3H)-pyrimidinedione. Grades: Highly Purified. CAS No. 75500-03-7. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
1,3-Dibutyl-5,6-diaminouracil
Intermediate in the preparation of disubstituted Xanthine derivatives. Group: Biochemicals. Alternative Names: 5,6-Diamino-1,3-dibutyl-2,4(1H,3H)-pyrimidinedione. Grades: Highly Purified. CAS No. 52998-23-9. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
1,3-Dimethyl-2'-deoxypseudoUridine
Compound 1,3-dimethyl-2'-deoxypseudoUridine is a C-nucleoside isomer of 1,3-dimethyl-2'-deoxyuridine. The 1,3-dimethyl-2'-deoxypseudoUridine can be synthesized from 1,3-dimethylpseudoUridine which can be obtained directly by treatment of pseudoUridine with dimethylformamide dimethyl acetal. Synonyms: (1R)-1,4-Anhydro-2-deoxy-1-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-erythro-pentitol; 5-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione; 2,4(1H,3H)-Pyrimidinedione, 5-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3-dimethyl-. Grade: ≥97%. CAS No. 65358-16-9. Molecular formula: C11H16N2O5. Mole weight: 256.26.
1,3-Dimethyl-6-sulfanylidene-1,3-diazinane-2,4-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,4 -Pyrimidinedione,dihydro-1,3-dimethyl-6-thioxo-, 36235-72-0. Product Category: Heterocyclic Organic Compound. CAS No. 36235-72-0. Molecular formula: C6H8N2O2S. Mole weight: 172.204920 [g/mol]. Purity: 0.96. IUPACName: 1,3-dimethyl-6-sulfanylidene-1,3-diazinane-2,4-dione. Canonical SMILES: CN1C(=O)CC(=S)N(C1=O)C. Product ID: ACM36235720. Alfa Chemistry ISO 9001:2015 Certified.
1,3-DimethylpseudoUridine
1,3-DimethylpseudoUridine is a modified nucleoside primarily known for its role in RNA biology. It's often used in biomedical research to study diseases like cancer and viral infections, and its influence on drug efficacy, especially RNA-based therapies. Synonyms: N1,N3-Dimethylpseudouridine; (1S)-1,4-Anhydro-1-(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol; 5-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione; 2,4(1H,3H)-Pyrimidinedione, 1,3-dimethyl-5-β-D-ribofuranosyl-. Grade: ≥97%. CAS No. 64272-68-0. Molecular formula: C11H16N2O6. Mole weight: 272.25.
1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phos-phino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil, a potent agent for the treatment of human immunodeficiency virus (HIV) infections, functions as a viral replication inhibitor by suppressing the reverse transcriptase enzyme. Its intricate molecular structure reflects the sophisticated nature of modern pharmaceuticals, which require cutting-edge research and development to ultimately undo the feats of viruses and other elusive adversaries. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[(5E)-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]-. Grade: ≥95%. CAS No. 2361324-80-1. Molecular formula: C24H40N4O9P2. Mole weight: 590.54.
1-[(5E)-5,6-Dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil, an extraordinary biomedicine, manifests its potential as a breakthrough antiviral agent. By adeptly targeting the viral uracil-DNA glycosylase enzyme, it inhibits viral replication and hinders viral DNA synthesis. Its molecular architecture, distinctive and resolute, engenders unrivaled selectivity and efficacy across diverse viral strains. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[(5E)-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]-; 1-[(2R,3R,4R,5R)-5-[(E)-2-diethoxyphosphorylethenyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione. Grade: ≥95%. CAS No. 2095417-05-1. Molecular formula: C15H23N2O8P. Mole weight: 390.33.
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